Abstract: The invention provides anti-KLK7 antibodies, anti-KLK5 antibodies, anti-KLK5/KLK7 multispecific antibodies, and methods of using the same.

Abstract: The replaceable mouthpiece includes a body having a first body end and a second body end. The first body end defines an outlet. The second body end defines a first opening coupleable to the aerosol-generating device. The replaceable mouthpiece includes two or more pillars disposed within the body and extending towards the second end.

Abstract: Systems and methods for generating user interface elements associated with a guided workout are disclosed herein. For example, by analyzing location data associated with a user device, along with digital content corresponding to the guided workout, the system may generate user interface elements including graphical representations, segmented timelines, and performance metrics associated with a user's progress and performance while consuming the guided workout content. These interface elements may be displayed to the user during and/or after the workout and may allow for user interaction to view varying levels of detail associated with the interface elements.

Abstract: The invention provides anti-KLK7 antibodies, anti-KLK5 antibodies, anti-KLK5/KLK7 multispecific antibodies, and methods of using the same.

Abstract: Methods, systems and computer program products are provided for transaction log validation in a database transaction log service. A transaction log service may perform egress validation to confirm transaction logs match previously served transaction logs and are free of corruption. A transaction log service may determine whether a transaction log (e.g., in the form of a log block) was previously served based on transaction log (e.g., log block) identity indicating a position in a logical stream of transaction logs (e.g., log blocks). Egress validation may improve log service reliability by providing an added layer of defense against corruption of a transaction log payload.

Abstract: Methods, systems, and computer program products are provided for consolidating transaction log requests and transaction logs in a database transaction log service. A scalable log service may manage log requests and logs to reduce resource consumption, such as memory and I/O. Log requests may be managed by consolidating (e.g., organizing, merging and/or de-duplicating) the log requests. Transaction log requests may be mapped to read requests for transaction log storage devices in less than a one-to-one ratio. Transaction logs may be managed by using the consolidated log requests to consolidate (e.g., and prefetch) transaction logs from multiple cache and/or storage tiers to a log pool cache. Log requests may be served from the log pool cache.

Abstract: Systems and methods to maintain inventory location data in an enterprise inventory management system, wherein the system includes a global inventory database subsystem for cataloging a plurality of inventory items, each of the inventory items identified in the database by at least a unique identification code and a physical location. The system, and related method, detects, using a motion detection subsystem, movement within a region between a first physical zone and a second physical zone; enables, in response to detecting movement, an RFID interrogator subsystem; identifies, utilizing the RF interrogator subsystem, any inventory items moving from the first physical zone to the second physical zone; and, reports, to the global inventory database subsystem, the identity of each identified inventory item, whereby the global inventory database system can update the physical location of each item from the first physical zone to the second physical zone.

Abstract: Methods, systems, and computer program products are provided for consolidating transaction log requests and transaction logs in a database transaction log service. A scalable log service may manage log requests and logs to reduce resource consumption, such as memory and I/O. Log requests may be managed by consolidating (e.g., organizing, merging and/or de-duplicating) the log requests. Transaction log requests may be mapped to read requests for transaction log storage devices in less than a one-to-one ratio. Transaction logs may be managed by using the consolidated log requests to consolidate (e.g., and prefetch) transaction logs from multiple cache and/or storage tiers to a log pool cache. Log requests may be served from the log pool cache.

Abstract: Methods, systems and computer program products are provided for transaction log validation in a database transaction log service. A transaction log service may perform egress validation to confirm transaction logs match previously served transaction logs and are free of corruption. A transaction log service may determine whether a transaction log (e.g., in the form of a log block) was previously served based on transaction log (e.g., log block) identity indicating a position in a logical stream of transaction logs (e.g., log blocks). Egress validation may improve log service reliability by providing an added layer of defense against corruption of a transaction log payload.

Abstract: Methods, systems and computer program products are provided for asynchronous processing of transaction log requests in a database transaction log service. A scalable log service may continuously process log requests. Log request processing may be paused and resumed without reducing log service processing capabilities. Log service threads executing a request that pauses may proceed to process other tasks in the same request or tasks for other new or partially processed requests. Any of multiple log service threads may resume processing of a paused request. Requests may be paused by preserving an execution state and deferring the request from a work queue to a deferral queue. Resumed requests may shift from a deferral queue to a work queue following a wait point.

Abstract: A method, system and non-transitory computer-readable medium used for testing a plurality of circuits to determine open surfaces are disclosed. The method includes: receiving one or more of attack techniques, and known open surfaces; carrying out attacks on a circuit to determine vulnerable surfaces of the circuit; determining when new open surfaces exist in the circuit; updating an attack plan based on the new open surfaces; carrying out the attack plan; generating a report of the open and vulnerable surfaces; and updating a repository to include new attack techniques against newly discovered open surfaces of the circuit.

Abstract: Described herein are compositions comprising universal donor natural killer (NK) cells, populations of such cells, methods of obtaining and preparing such cells, and methods of use of such cells and compositions in medical treatment of cancers and infectious disease.

Abstract: A method, system and non-transitory computer-readable medium used for testing a plurality of circuits to determine open surfaces are disclosed. The method includes: receiving one or more of attack techniques, and known open surfaces; carrying out attacks on a circuit to determine vulnerable surfaces of the circuit; determining when new open surfaces exist in the circuit; updating an attack plan based on the new open surfaces; carrying out the attack plan; generating a report of the open and vulnerable surfaces; and updating a repository to include new attack techniques against newly discovered open surfaces of the circuit.

Abstract: Systems and methods to maintain inventory location data in an enterprise inventory management system, wherein the system includes a global inventory database subsystem for cataloging a plurality of inventory items, each of the inventory items identified in the database by at least a unique identification code and a physical location. The system, and related method, detects, using a motion detection subsystem, movement within a region between a first physical zone and a second physical zone; enables, in response to detecting movement, an RFID interrogator subsystem; identifies, utilizing the RF interrogator subsystem, any inventory items moving from the first physical zone to the second physical zone; and, reports, to the global inventory database subsystem, the identity of each identified inventory item, whereby the global inventory database system can update the physical location of each item from the first physical zone to the second physical zone.

Abstract: A hot melt adhesive (HMA) composition includes (A) from 1-60 wt % of a block composite compatibilizer comprising (i) a hard polymer that includes propylene, (ii) a soft polymer that includes ethylene, and (iii) a block copolymer having a soft block and a hard block, the hard block of the block copolymer having the same composition as the hard polymer of the block composite compatibilizer and the soft block of the block copolymer having the same composition as the soft polymer of the block composite compatibilizer; (B) from 1-70 wt % of a tackifier; (C) from 1-40 wt % of at least one selected from the group of a wax and an oil; and (D) Optionally, from greater than zero to 97 wt % of a polymer component that includes an ethylene-based polymer and/or a propylene-based polymer.

Abstract: A composition includes (A) 30-95 wt % of a random or homogeneous propylene-based interpolymer having: (i) a comonomer content of at least one of C2 and C4-10 ?-olefins of 7 wt % to 49 wt % based on the total weight of the propylene-based interpolymer, (ii) a density of 0.90 g/cc or less, and (iii) an MFR of 1 g/10 min or greater (230° C./2.16 kg); and (B) 5-70 wt % of a block composite nucleator comprising: (1) a first polymer that includes polypropylene; (2) a second polymer that includes an alpha-olefin based polymer, the alpha-olefin being selected from at least one of a C2 and C4-10 ?-olefins, and (3) a block copolymer having a first segment and a second segment, the first segment of the block copolymer having the same composition as the first polymer in the block composite nucleator and the second segment of the block copolymer having the same composition as the second polymer of the block composite nucleator.

Abstract: Embodiments of the present invention comprise pre-fabricated domed skylight panel assemblies for use within steel decking systems. The skylight within the pre-fabricated domed skylight panel assembly is domed. Extending from the width-wise ends of the domed portion are respective skylight end extension portions for overlapping with adjacent steel decking panels or for coupling within an aperture of a decking panel. Further, extending from the length-wise edges of the dome portion are skylight edges configured for connection to decking panel edges (e.g., male and female rail edges or panel edges) that are configured for connection to edges of adjacent decking panels. The pre-fabricated domed skylight panel assemblies provide the desired light into the building, structural support in the steel decking system, ease of shipping of the domed skylight panel assemblies, ease of installation of the domed skylight panel assemblies at the building site, and a water tight seal.

Abstract: A hot melt adhesive (HMA) composition includes (A) from 1-60 wt % of a block composite compatibilizer comprising (i) a hard polymer that includes propylene, (ii) a soft polymer that includes ethylene, and (iii) a block copolymer having a soft block and a hard block, the hard block of the block copolymer having the same composition as the hard polymer of the block composite compatibilizer and the soft block of the block copolymer having the same composition as the soft polymer of the block composite compatibilizer; (B) from 1-70 wt % of a tackifier; (C) from 1-40 wt % of at least one selected from the group of a wax and an oil; and (D) Optionally, from greater than zero to 97 wt % of a polymer component that includes an ethylene-based polymer and/or a propylene-based polymer.

Abstract: A composition includes (A) 30-95 wt % of a random or homogeneous propylene-based interpolymer having: (i) a comonomer content of at least one of C2 and C4-10 ?-olefins of 7 wt % to 49 wt % based on the total weight of the propylene-based interpolymer, (ii) a density of 0.90 g/cc or less, and (iii) an MFR of 1 g/10 min or greater (230° C./2.16 kg); and (B) 5-70 wt % of a block composite nucleator comprising: (1) a first polymer that includes polypropylene; (2) a second polymer that includes an alpha-olefin based polymer, the alpha-olefin being selected from at least one of a C2 and C4-10 ?-olefins, and (3) a block copolymer having a first segment and a second segment, the first segment of the block copolymer having the same composition as the first polymer in the block composite nucleator and the second segment of the block copolymer having the same composition as the second polymer of the block composite nucleator.

Abstract: Embodiments of the present invention comprise pre-fabricated domed skylight panel assemblies for use within steel decking systems. The skylight within the pre-fabricated domed skylight panel assembly is domed. Extending from the width-wise ends of the domed portion are respective skylight end extension portions for overlapping with adjacent steel decking panels or for coupling within an aperture of a decking panel. Further, extending from the length-wise edges of the dome portion are skylight edges configured for connection to decking panel edges (e.g., male and female rail edges or panel edges) that are configured for connection to edges of adjacent decking panels. The pre-fabricated domed skylight panel assemblies provide the desired light into the building, structural support in the steel decking system, ease of shipping of the domed skylight panel assemblies, ease of installation of the domed skylight panel assemblies at the building site, and a water tight seal.