Abstract: A monitoring device for an animal comprising a body with an aperture for receiving a first part of an ear tag that extends through an ear of the animal. The body comprises a surface area for contacting the ear of the animal. The monitoring device further comprises a processor, a battery and a network. The monitoring device is configured such that, in use, when the first part of an ear tag extends through the ear of the animal and the aperture of the monitoring device, and the second part of the ear tag is fixated to the first part, the monitoring device is positioned between the ear tag and the ear of the animal so that the surface area of the body of the monitoring device is in contact with the ear of the animal to obtain the information indicative of at least the temperature of the animal.

Abstract: A monitoring device for an animal comprising a body with an aperture for receiving a first part of an ear tag that extends through an ear of the animal. The body comprises a surface area for contacting the ear of the animal. The monitoring device further comprises a processor, a battery and a network. The monitoring device is configured such that, in use, when the first part of an ear tag extends through the ear of the animal and the aperture of the monitoring device, and the second part of the ear tag is fixated to the first part, the monitoring device is positioned between the ear tag and the ear of the animal so that the surface area of the body of the monitoring device is in contact with the ear of the animal to obtain the information indicative of at least the temperature of the animal.

Abstract: A monitoring device for an animal comprising a body with an aperture for receiving a first part of an ear tag that extends through an ear of the animal. The body comprises a surface area for contacting the ear of the animal. The monitoring device further comprises a processor, a battery and a network. The monitoring device is configured such that, in use, when the first part of an ear tag extends through the ear of the animal and the aperture of the monitoring device, and the second part of the ear tag is fixated to the first part, the monitoring device is positioned between the ear tag and the ear of the animal so that the surface area of the body of the monitoring device is in contact with the ear of the animal to obtain the information indicative of at least the temperature of the animal.

Abstract: Systems and methods for smart sensors are provided. A smart sensor includes: a computer processor; a microphone; and a memory storing a voice control module. The voice control module may be configured to: resolve a first voice command received by the microphone and determine a first identity of a first registered user of a plurality of registered users based on the first voice command. In embodiments, resolving the first voice command includes determining a first instruction. In additional embodiments, the smart sensor may be configured to carry out the first instruction based on first user data associated with the first user.

Abstract: Systems and methods for smart sensors are provided. A smart sensor includes: a case; a power adapter configured to be plugged directly into an electrical outlet; a computer processor; a microphone; a speaker; a camera; at least one sensor; a control switch; a sync button; a USB port; and a memory storing: an operating system; a voice control module; a peer interaction module; a remote interaction module; and a cognitive module. In embodiments, the power adapter includes prongs that extend from a back side of the case, and the microphone, the speaker, the camera, and the at least one sensor are on a front side of the case opposite the back side of the case.

Abstract: Systems and methods for smart sensors are provided. A smart sensor includes: a case; a power adapter configured to be plugged directly into an electrical outlet; a computer processor; a microphone; a speaker; a camera; at least one sensor; a control switch; a sync button; a USB port; and a memory storing: an operating system; a voice control module; a peer interaction module; a remote interaction module; and a cognitive module. In embodiments, the power adapter includes prongs that extend from a back side of the case, and the microphone, the speaker, the camera, and the at least one sensor are on a front side of the case opposite the back side of the case.

Abstract: Systems and methods for smart sensors are provided. A smart sensor includes: a case; a power adapter configured to be plugged directly into an electrical outlet; a computer processor; a microphone; a speaker; a camera; at least one sensor; a control switch; a sync button; a USB port; and a memory storing: an operating system; a voice control module; a peer interaction module; a remote interaction module; and a cognitive module. In embodiments, the power adapter includes prongs that extend from a back side of the case, and the microphone, the speaker, the camera, and the at least one sensor are on a front side of the case opposite the back side of the case.

Abstract: A method, computer program product, and a system where a process(s) generates a data model for a given environment; the model includes a listing of consumable items utilized in the environment and structured and unstructured data sources relevant to the consumable items utilized in the environment. The processor(s) machine learns factors related to supply and demand for the consumable items, based on ingesting structured and unstructured data from the data sources indicated in the data model and extracting occurrences of data representing consumable items coupled with occurrences of the factors. The processor(s) generates correlations quantifiable correlations between factors and consumable items and updates the model with the correlations. The processor(s) obtains, for a future time, a request for replenishment of the consumable items for the environment. The processor(s) uses the model to generate a replenishment plan for the environment for the given time period, based on ranking the consumable items.

Abstract: Systems and methods for smart sensors are provided. A smart sensor includes: a case; a power adapter configured to be plugged directly into an electrical outlet; a computer processor; a microphone; a speaker; a camera; at least one sensor; a control switch; a sync button; a USB port; and a memory storing: an operating system; a voice control module; a peer interaction module; a remote interaction module; and a cognitive module. In embodiments, the power adapter includes prongs that extend from a back side of the case, and the microphone, the speaker, the camera, and the at least one sensor are on a front side of the case opposite the back side of the case.

Abstract: The invention provides compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with the activity of Cannabinoid Receptor 1 (CB1).

Abstract: The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated B cell activities, particularly diseases or disorders that involve aberrant activation of inositol 1,4,5-trisphosphate 3-kinase B (ITPKb).

Abstract: The invention provides compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with the activity of Cannabinoid Receptor 1 (CB1).

Abstract: Disclosed herein are various methods for synthesizing compounds that modulate thrombopoietin activity. Also disclosed are intermediates useful for the preparation of these compounds.

Abstract: Disclosed herein are compounds of Formula I: and pharmaceutically acceptable salts, esters, amides, and prodrugs thereof. Certain of such compounds are selective glucocorticoid receptor modulators and/or selective glucocorticoid binding agents. Also disclosed are methods of making and using such compounds, including, but not limited to, using such compounds for treating various conditions.

Abstract: Disclosed herein are compounds, pharmaceutical compositions comprising the same, methods of modulating the activity a thrombopoietin receptor using the same, methods of identifying compounds as thrombopoietin receptor modulators, and methods of treating disease by administering a compound of the invention to a patient in need thereof.

Abstract: Disclosed herein are novel diazenyl pyrazole compounds and related compounds. Also disclosed herein are methods of using these compounds for the treatment of diseases and conditions associated with modulating a thrombopoietin activity.

Abstract: Disclosed herein are compounds of Formula (I), (II), and (III) pharmaceutical compositions comprising the same, methods of modulating the activity a thrombopoietin receptor using the same, methods of identifying compounds as thrombopoietin receptor modulators, and methods of treating disease by administering a compound of the invention to a patient in need thereof.