Abstract: The present disclosure relates to acetaminophen protein adducts and methods of diagnosing acetaminophen toxicity using the acetaminophen protein adducts.

Abstract: The present disclosure relates to acetaminophen protein adducts and methods of diagnosing acetaminophen toxicity using the acetaminophen protein adducts.

Abstract: The present disclosure relates to acetaminophen protein adducts and methods of diagnosing acetaminophen toxicity using the acetaminophen protein adducts.

Abstract: The present disclosure relates to acetaminophen protein adducts and methods of diagnosing acetaminophen toxicity using the acetaminophen protein adducts. The present disclosure provides acetaminophen (APAP)-protein adducts and methods of detecting acetaminophen-induced toxicity in a subject using APAP-protein adducts. One aspect of the present disclosure provides an APAP-protein adduct for diagnosing acetaminophen-induced toxicity. According to the present disclosure, the inventors have identified proteins that are modified by N-acetyl-pbenzoquinoneimine (NAPQI) in subjects with acetaminophen-induced toxicity. Non-limiting examples of proteins modified by NAPQI include betaine-homocysteine S-methyltransferase 1, cytoplasmic aspartate aminotransferase, 1,4-alpha-glucan branching enzyme, formimidoyltransferase-cyclodeaminase, and dystrophin.

Abstract: The present disclosure relates to acetaminophen protein adducts and methods of diagnosing acetaminophen toxicity using the acetaminophen protein adducts. The present disclosure provides acetaminophen (APAP)-protein adducts and methods of detecting acetaminophen-induced toxicity in a subject using APAP-protein adducts. One aspect of the present disclosure provides an APAP-protein adduct for diagnosing acetaminophen-induced toxicity. According to the present disclosure, the inventors have identified proteins that are modified by N-acetyl-pbenzoquinoneimine (NAPQI) in subjects with acetaminophen-induced toxicity. Non-limiting examples of proteins modified by NAPQI include betaine-homocysteine 5-methyltransferase 1, cytoplasmic aspartate aminotransferase, 1,4-alpha-glucan branching enzyme, formimidoyltransferase-cyclodeaminase, and dystrophin.

Abstract: The present invention describes devices and methods for detecting and measuring the amount of acetaminophen-protein adducts in a sample.

Abstract: The present invention describes devices and methods for detecting and measuring the amount of acetaminophen-protein adducts in a sample.

Abstract: A cigarette kit includes a case that has a plurality of monolithically formed sidewalls defining a cavity therebetween. One sidewall defines a planar bottom surface of the case. The case includes a lid pivotally conjoined therewith and has a fulcrum axis about which the lid is adaptable. An insert is positioned within the cavity and has a first top surface offset and parallel from the bottom surface. A plurality of cigarettes are storable in the cavity wherein selected ones of the cigarettes have bottom end portions situated on the bottom surface and other ones of the cigarettes have bottom end portions situated on the first top surface respectively. The cigarettes have uniquely dimensioned longitudinal lengths that include at least two cigarettes selected from the group including a small cigarette, a medium cigarette, a large cigarette, and any combination thereof.

Abstract: A method for manufacturing a puzzle post card comprising providing a first backing, adhering a picture to one surface of said backing, adhering said first backing to a second backing containing an address means whereby only the perimeter of said first backing is adhered to said second backing, cutting said first backing in the non-adhered to portion to form a puzzle, adhering a plastic cover over said puzzle to hold said puzzle in place during mailing.