Abstract: Described herein are compounds of Formula I, wherein the variables are defined herein, their use as HSD17B13 inhibitors and/or degraders, pharmaceutical compositions containing such compounds and their use to treat, for example, NAFLD and NASH.

Abstract: A modeling system determines a physical location of a device in a store and a virtual location in a virtual model of a store that corresponds to the physical location. The modeling system determines, from the virtual model, a subset of model data based on the virtual location. The model data comprises store location data applicable to the entire store, shelf data applicable to shelves in the store, and planogram data applicable to the shelves and products associated with the shelves. The subset of model data comprises the store location data, a subset of the shelf data applicable to at least a shelf within a predefined distance of the physical location of the device, and a subset of the planogram data applicable to at least the shelf and a product associated with the shelf. The modeling system generates a presentation of a scene based on the subset of model data.