Patents by Inventor Deani L. Cooper

Deani L. Cooper has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and kits for fractionating a population of DNA molecules based on the presence or absence of a base-pair mismatch utilizing mismatch repair systems
    Patent number: 5556750
    Abstract: A diagnostic method for detecting a base pair mismatch in a DNA duplex, comprising the steps of contacting at least one strand of a first DNA molecule with the complementary strand of a second DNA molecule under conditions such that base pairing occurs contacting a DNA duplex potentially containing a base pair mismatch with a mispair recognition protein under conditions suitable for the protein to form a specific complex only with the DNA duplex having a base pair mismatch, and not with a DNA duplex lacking a base pair mismatch, and detecting any complex as a measure of the presence of a base pair mismatch in the DNA duplex.
    Type: Grant
    Filed: November 1, 1993
    Date of Patent: September 17, 1996
    Assignee: Duke University
    Inventors: Paul L. Modrich, Shin-San Su, Karin G. Au, Robert S. Lahue, Deani L. Cooper, Leroy Worth, Jr.