Abstract: The invention in this application is a decision-support system that utilizes single system design (SSD) and a proprietary algorithm to determine real change is for each individual patient. It pinpoints right medication and dosage for an individual patient, targets standards for functionality, called Activities of Daily Living (ADLs), and Quality of Life Indicators (QoLIs) to maximize personal health and satisfaction. Further, the system has as hallmarks a specific communication system, provision of coordination of services and a continuum of care for seamless delivery of treatment targeted to the needs of an individual patient and his/her care network. It incorporates data collected from genomic testing, patient entry, and automated devices. It is a safety-enhancing, cost-saving, time-saving system that will address placebo effect. It will utilize a variety of technologies to gather data with flexibility for patient needs. It will utilize machine learning for added safety enhancement.