Patents by Inventor Debabrata Banerjee
Debabrata Banerjee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11888650Abstract: An overlay network is enhanced to provide traffic delivery using anycast and end user mapping. An anycast IP address is associated with sets of forwarding machines positioned in the overlay network. These locations correspond with IP addresses for zero rated billing traffic. In response to receipt at a forwarding machine of a packet, the machine issues an end user mapping request to the mapping mechanism. The mapping request has an IP address associated with the client from which the end user request originates. The mapping mechanism resolves the request and provides a response to the request. The response is an IP address associated with a set of server machines distinct from the forwarding machine. The forwarding machine encapsulates the packet and proxies the connection to the identified server. The server receives the connection, decapsulates the request, and processes the packet. The server machine responds to the requesting client directly.Type: GrantFiled: October 25, 2022Date of Patent: January 30, 2024Assignee: Akamai Technologies, Inc.Inventors: Igor Lubashev, Elizabeth L. Borowsky, Stephen Hill, Katharine Jenkins, Debabrata Banerjee, Noam Freedman, Marcelo Torres
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Publication number: 20230040752Abstract: An overlay network is enhanced to provide traffic delivery using anycast and end user mapping. An anycast IP address is associated with sets of forwarding machines positioned in the overlay network. These locations correspond with IP addresses for zero rated billing traffic. In response to receipt at a forwarding machine of a packet, the machine issues an end user mapping request to the mapping mechanism. The mapping request has an IP address associated with the client from which the end user request originates. The mapping mechanism resolves the request and provides a response to the request. The response is an IP address associated with a set of server machines distinct from the forwarding machine. The forwarding machine encapsulates the packet and proxies the connection to the identified server. The server receives the connection, decapsulates the request, and processes the packet. The server machine responds to the requesting client directly.Type: ApplicationFiled: October 25, 2022Publication date: February 9, 2023Inventors: Igor Lubashev, Elizabeth L. Borowsky, Stephen Hill, Katharine Jenkins, Debabrata Banerjee, Noam Freedman, Marcelo Torres
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Patent number: 11483176Abstract: An overlay network is enhanced to provide traffic delivery using anycast and end user mapping. An anycast IP address is associated with sets of forwarding machines positioned in the overlay network. These locations correspond with IP addresses for zero rated billing traffic. In response to receipt at a forwarding machine of a packet, the machine issues an end user mapping request to the mapping mechanism. The mapping request has an IP address associated with the client from which the end user request originates. The mapping mechanism resolves the request and provides a response to the request. The response is an IP address associated with a set of server machines distinct from the forwarding machine. The forwarding machine encapsulates the packet and proxies the connection to the identified server. The server receives the connection, decapsulates the request, and processes the packet. The server machine responds to the requesting client directly.Type: GrantFiled: October 12, 2020Date of Patent: October 25, 2022Assignee: Akamai Technologies, Inc.Inventors: Igor Lubashev, Elizabeth L. Borowsky, Stephen Hill, Katharine Jenkins, Debabrata Banerjee, Noam Freedman, Marcelo Torres
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Publication number: 20210028959Abstract: An overlay network is enhanced to provide traffic delivery using anycast and end user mapping. An anycast IP address is associated with sets of forwarding machines positioned in the overlay network. These locations correspond with IP addresses for zero rated billing traffic. In response to receipt at a forwarding machine of a packet, the machine issues an end user mapping request to the mapping mechanism. The mapping request has an IP address associated with the client from which the end user request originates. The mapping mechanism resolves the request and provides a response to the request. The response is an IP address associated with a set of server machines distinct from the forwarding machine. The forwarding machine encapsulates the packet and proxies the connection to the identified server. The server receives the connection, decapsulates the request, and processes the packet. The server machine responds to the requesting client directly.Type: ApplicationFiled: October 12, 2020Publication date: January 28, 2021Inventors: Igor Lubashev, Elizabeth L. Borowsky, Stephen Hill, Katharine Jenkins, Debabrata Banerjee, Noam Freedman, Marcelo Torres
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Patent number: 10805110Abstract: An overlay network is enhanced to provide traffic delivery using anycast and end user mapping. An anycast IP address is associated with sets of forwarding machines positioned in the overlay network. These locations correspond with IP addresses for zero rated billing traffic. In response to receipt at a forwarding machine of a packet, the machine issues an end user mapping request to the mapping mechanism. The mapping request has an IP address associated with the client from which the end user request originates. The mapping mechanism resolves the request and provides a response to the request. The response is an IP address associated with a set of server machines distinct from the forwarding machine. The forwarding machine encapsulates the packet and proxies the connection to the identified server. The server receives the connection, decapsulates the request, and processes the packet. The server machine responds to the requesting client directly.Type: GrantFiled: March 26, 2016Date of Patent: October 13, 2020Assignee: Akamai Technologies, Inc.Inventors: Igor Lubashev, Elizabeth L. Borowsky, Stephen Hill, Katharine Jenkins, Debabrata Banerjee, Noam Freedman, Marcelo Torres
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Patent number: 9519964Abstract: A system and methods for generating 3D images from 2D bioluminescent images and visualizing tumor locations are provided. A plurality of 2D bioluminescent images of a subject are acquired using any suitable bioluminescent imaging system. The 2D images are registered to align each image and to compensate for differences between adjacent images. After registration, corresponding features are identified between consecutive sets of 2D images. For each corresponding feature identified in each set of 2D images, an orthographic projection model is applied, such that rays are projected through each point in the feature. The intersection points of the rays are plotted in a 3D image space. All of the 2D images are processed in the same manner, such that a resulting 3D image of a tumor is generated.Type: GrantFiled: July 10, 2012Date of Patent: December 13, 2016Assignee: Rutgers, The State University of New JerseyInventors: Dimitris Metaxas, Debabrata Banerjee, Xiaolei Huang
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Publication number: 20160315857Abstract: An overlay network is enhanced to provide traffic delivery using anycast and end user mapping. An anycast IP address is associated with sets of forwarding machines positioned in the overlay network. These locations correspond with IP addresses for zero rated billing traffic. In response to receipt at a forwarding machine of a packet, the machine issues an end user mapping request to the mapping mechanism. The mapping request has an IP address associated with the client from which the end user request originates. The mapping mechanism resolves the request and provides a response to the request. The response is an IP address associated with a set of server machines distinct from the forwarding machine. The forwarding machine encapsulates the packet and proxies the connection to the identified server. The server receives the connection, decapsulates the request, and processes the packet. The server machine responds to the requesting client directly.Type: ApplicationFiled: March 26, 2016Publication date: October 27, 2016Inventors: Igor Lubashev, Elizabeth L. Borowsky, Steven Hill, Katharine Jenkins, Debabrata Banerjee, Noam Freedman, Marcelo Torres
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Patent number: 9314497Abstract: The instant invention provides amino acid sequences competing with E2F for DNA binding. Methods of using said amino acid sequences for treatment of hormone-refractory prostate cancer are also provided.Type: GrantFiled: September 2, 2014Date of Patent: April 19, 2016Assignee: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEYInventors: Joseph R. Bertino, Debabrata Banerjee, Tamara Minko, Olga B. Garbuzenko, Xiaoqi Xie, John E. Kerrigan, Emine E. Abali, Kathleen W. Scotto
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Publication number: 20150202248Abstract: The instant invention provides amino acid sequences competing with E2F for DNA binding. Methods of using said amino acid sequences for treatment of hormone-refractory prostate cancer are also provided.Type: ApplicationFiled: September 2, 2014Publication date: July 23, 2015Inventors: Joseph R. Bertino, Debabrata Banerjee, Tamara Minko, Olga B. Garbuzenko, Xiaoqi Xie, John E. Kerrigan, Emine E. Abali, Kathleen W. Scotto
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Patent number: 8822421Abstract: The instant invention provides amino acid sequences competing with E2F for DNA binding. Methods of using said amino acid sequences for treatment of hormone-refractory prostate cancer are also provided.Type: GrantFiled: October 14, 2011Date of Patent: September 2, 2014Assignee: Rutgers, The State University of New JerseyInventors: Joseph R. Bertino, Debabrata Banerjee, Tamara Minko, Olga B. Garbuzenko, Xiaoqi Xie, John E. Kerrigan, Emine E. Abali, Kathleen W. Scotto
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Publication number: 20130070992Abstract: A system and methods for generating 3D images from 2D bioluminescent images and visualizing tumor locations are provided. A plurality of 2D bioluminescent images of a subject are acquired using any suitable bioluminescent imaging system. The 2D images are registered to align each image and to compensate for differences between adjacent images. After registration, corresponding features are identified between consecutive sets of 2D images. For each corresponding feature identified in each set of 2D images, an orthographic projection model is applied, such that rays are projected through each point in the feature. The intersection points of the rays are plotted in a 3D image space. All of the 2D images are processed in the same manner, such that a resulting 3D image of a tumor is generated.Type: ApplicationFiled: July 10, 2012Publication date: March 21, 2013Inventors: Dimitris Metaxas, Debabrata Banerjee, Xiaolei Huang
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Publication number: 20120213706Abstract: Extracellular matrix bioscaffolds capable of supporting the formation and growth of tumors from tumor cells introduced thereto containing tumor associated macrophages and carcinoma-associated fibroblast-like cells cultured under conditions effective to provide a cellular matrix capable of supporting the formation and growth of tumors from tumor cells introduced to the matrix. Bioscaffold kits and methods for using the bioscaffolds for testing, identifying and development of known or novel anti-cancer therapeutics are also disclosed.Type: ApplicationFiled: November 12, 2009Publication date: August 23, 2012Applicant: UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEYInventors: Debabrata Banerjee, Pravin J. Mishra, Prasun J. Mishra, Hui Gao, John Glod
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Patent number: 8218836Abstract: A system and methods for generating 3D images (24) from 2D bioluminescent images (22) and visualizing tumor locations are provided. A plurality of 2D bioluminescent images of a subject are acquired during a complete revolution of an imaging system about a subject, using any suitable bioluminescent imaging system. After imaging, the 2D images are registered (20) according to the rotation axis to align each image and to compensate for differences between adjacent images. After registration (20), corresponding features are identified between consecutive sets of 2D image (22). For each corresponding feature identified in each set of 2D images an orthographic projection model (24) is applied, such that rays are projected through each point in the feature. The intersection point of the rays are plotted in a 3D image of a tumor is generated. The 3D image can be registered with a reference image of the subject, so that the shape and location of the tumor can be precisely visualized with respect to the subject.Type: GrantFiled: August 31, 2006Date of Patent: July 10, 2012Assignee: Rutgers, The State University of New JerseyInventors: Dimitris Metaxas, Debabrata Banerjee, Xiaolei Huang
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Publication number: 20120093919Abstract: The instant invention provides amino acid sequences competing with E2F for DNA binding. Methods of using said amino acid sequences for treatment of hormone-refractory prostate cancer are also provided.Type: ApplicationFiled: October 14, 2011Publication date: April 19, 2012Applicants: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY, UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEYInventors: Joseph R. Bertino, Debabrata Banerjee, Tamara Minko, Olga B. Garbuzenko, Xiaoqi Xie, John E. Kerrigan, Emine E. Abali, Kathleen W. Scotto
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Publication number: 20100240595Abstract: The present invention relates to combinations of Aplidine with Gemcitabine, and the use of these combinations in the treatment of cancer.Type: ApplicationFiled: October 20, 2008Publication date: September 23, 2010Applicant: PHARMA MAR ,S.A.Inventors: Giuseppe Longo Sorbello, Pravin Jaiprakash Mishra, Prasun Jaiprakash Mishra, Joseph Rocco Bertino, Debabrata Banerjee, José Maria Jimeno Donaque
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Publication number: 20100151004Abstract: Methods for the treatment of disorders, including cancer, are described which include administering to a subject a DNA methylation inhibitor and an antineoplastic agent. Compositions containing a DNA methylation inhibitor and an antineoplastic agent, which are useful in treating disorders including cancer, are also described. Additionally, methods useful for developing a prognosis for or diagnosing a subject's development of resistance to treatment with a chemotherapeutic agent are described.Type: ApplicationFiled: March 7, 2008Publication date: June 17, 2010Applicant: UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEYInventors: Debabrata Banerjee, Joseph R. Bertino, Rita Humeniuk, Prasun J. Mishra
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Publication number: 20090148013Abstract: A system and methods for generating 3D images (24) from 2D bioluminescent images (22) and visualizing tumor locations are provided. A plurality of 2D bioluminescent images of a subject are acquired during a complete revolution of an imaging system about a subject, using any suitable bioluminescent imaging system. After imaging, the 2D images are registered (20) according to the rotation axis to align each image and to compensate for differences between adjacent images. After registration (20), corresponding features are identified between consecutive sets of 2D image (22). For each corresponding feature identified in each set of 2D images an orthographic projection model (24) is applied, such that rays are projected through each point in the feature. The intersection point of the rays are plotted in a 3D image of a tumor is generated. The 3D image can be registered with a reference image of the subject, so that the shape and location of the tumor can be precisely visualized with respect to the subject.Type: ApplicationFiled: August 31, 2006Publication date: June 11, 2009Inventors: Dimitris Metaxas, Debabrata Banerjee, Xiaolei Huang
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Publication number: 20060003936Abstract: A method is provided for use in producing a selected protein in mammalian cells, and to cDNA molecules useful in the method, and fusion proteins produced from expression of the cDNA. In the method, cDNA encoding a fusion protein that includes a mammalian DHFR and the selected protein is introduced into mammalian cells such that it is expressed. The naturally occurring repression of DHFR translation is overcome by treatment of the cells with a folate or antifolate or similar composition. The relief from this repression extends to the selected protein which is the second part of the expressed fusion, such that the treatment results in controllable and enhanced production of the selected protein.Type: ApplicationFiled: August 26, 2005Publication date: January 5, 2006Inventors: Philipp Mayer-Kuckuk, Debabrata Banerjee, Joseph Bertino
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Patent number: 6887467Abstract: New mutant forms of human dihydrofolate reductase (DHFR) which have properties superior to the previously disclosed mutants have mutations at both amino acid 22 and amino acid 31. Specific mutant forms are Ser31Tyr22, Ser31Phe22, Gly31Tyr22, Gly31Phe22, Ala31Tyr22 and Ala31Phe22. The mutant DHFR of the invention may be used as a selectable marker, and to modify the genome of human cells, particularly bone marrow cells or peripheral blood stem cells, to render them resistant to chemotherapy using antifolate agents.Type: GrantFiled: August 27, 2003Date of Patent: May 3, 2005Assignee: Sloan-Kettering Institute for Cancer ResearchInventors: Joseph R. Bertino, Emine A. Ercikan-Abali, Debabrata Banerjee, Shin Mineishi, Michel Sadelain
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Publication number: 20040053836Abstract: A method is provided for use in producing a selected protein in mammalian cells, and to cDNA molecules useful in the method, and fusion proteins produced from expression of the cDNA. In the method, cDNA encoding a fusion protein that includes a mammalian DHFR and the selected protein is introduced into mammalian cells such that it is expressed. The naturally occurring repression of DHFR translation is overcome by treatment of the cells with a folate or antifolate or similar composition. The relief from this repression extends to the selected protein which is the second part of the expressed fusion, such that the treatment results in controllable and enhanced production of the selected protein.Type: ApplicationFiled: April 22, 2003Publication date: March 18, 2004Inventors: Philipp Mayer-Kuckuk, Debabrata Banerjee, Joseph Bertino