Patents by Inventor Debadyuti Ghosh

Debadyuti Ghosh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240293317
    Abstract: Lipid nanoparticles (LNPs) comprising biologically active poly nucleotides (e.g., RNAs) are provided. In some aspects, the LNP complexes are provided as aerosols and/or dry powders, such as for delivery to the lungs. Method of making and using such compositions are provided.
    Type: Application
    Filed: April 20, 2021
    Publication date: September 5, 2024
    Applicant: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
    Inventors: Hugh D.C. SMYTH, Hairui ZHANG, Debadyuti GHOSH, Jasmim LEAL, Melissa SOTO, Robert O. WILLIAMS, III
  • Publication number: 20230382951
    Abstract: The present disclosure is directed to the identification of peptides that cross the blood brain barrier and their use to transport diagnostic and therapeutic payloads into the brain.
    Type: Application
    Filed: October 21, 2021
    Publication date: November 30, 2023
    Applicant: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
    Inventors: Debadyuti GHOSH, Xiujuan PENG
  • Publication number: 20230218773
    Abstract: Provided herein are methods for producing an albumin drug conjugate. The albumin and dmg may be mixed ex vivo prior to administration. Further provided herein are methods of treating cancer comprising administering the albumin drug conjugate.
    Type: Application
    Filed: April 30, 2021
    Publication date: July 13, 2023
    Applicant: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
    Inventors: Debadyuti GHOSH, Xinquan LIU
  • Publication number: 20220023204
    Abstract: Dry powder compositions comprising biologically active polynucleotide molecules and methods for the manufacture of such dry powders are provided. In some aspects, dry powders of the embodiment comprise expressible or regulatory (e.g., siRNA) polynucleotide molecules complexed with nanoparticles. Dry powders comprising viable virus and bacteria are also provided.
    Type: Application
    Filed: April 20, 2021
    Publication date: January 27, 2022
    Applicant: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
    Inventors: Hugh D.C. SMYTH, Hairui ZHANG, Zhengrong CUI, Jieliang WANG, Haiyue XU, Yajie ZHANG, Debadyuti GHOSH, Jasmim LEAL, Melissa SOTO, Robert O. WILLIAMS, III, Chaeho MOON, Sawittree SAHAKIJPIJARN
  • Publication number: 20210284688
    Abstract: The present invention relates to a screening method to identify mucus-penetrating compounds. In certain aspects, the present invention relates to mucus-penetrating peptides and constructs comprising an agent, such as a therapeutic agent, imaging agent or diagnostic agent, conjugated to a mucus-penetrating peptide.
    Type: Application
    Filed: July 14, 2017
    Publication date: September 16, 2021
    Inventors: Debadyuti GHOSH, Hugh SMYTH
  • Patent number: 10041951
    Abstract: An imaging probe can include a photoluminescent carbon nanostructure configured to emit a wavelength of light detectable through living tissue, and a targeting moiety including a first binding partner configured to interact with a second binding partner.
    Type: Grant
    Filed: January 31, 2013
    Date of Patent: August 7, 2018
    Assignee: Massachusetts Institute of Technology
    Inventors: Hyunjung Yi, Debadyuti Ghosh, Jifa Qi, Angela M. Belcher, Michael S. Strano, Neelkanth M. Bardhan
  • Publication number: 20130230464
    Abstract: An imaging probe can include a photoluminescent carbon nanostructure configured to emit a wavelength of light detectable through living tissue, and a targeting moiety including a first binding partner configured to interact with a second binding partner.
    Type: Application
    Filed: January 31, 2013
    Publication date: September 5, 2013
    Inventors: Hyunjung Yi, Debadyuti Ghosh, Jifa Qi, Angela M. Belcher, Michael S. Strano