Patents by Inventor Debanjan Sarkar
Debanjan Sarkar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11661471Abstract: Among other things, the present disclosure provides compositions and methods for an elastomeric cross-linked polyester material. Such an elastomeric cross-linked polyester material, in some embodiments, comprises a plurality of polymeric units of the general formula (-A-B-)p, wherein p is an integer greater than 1; and a plurality of urethane cross-links each of which covalently links two polymeric units to one another, which two linked polymeric unit each had at least one free hydroxyl or amino group prior to formation of the crosslink.Type: GrantFiled: January 11, 2022Date of Patent: May 30, 2023Assignees: MASSACHUSETTS INSTITUTE OF TECHNOLOGY, THE BRIGHAM AND WOMEN'S HOSPITAL, INC., BIOCANT-CENTER OF INNOVATION AND BIOTECHNOLOGYInventors: Robert S. Langer, Jeffrey M. Karp, Maria Jose Maio Nunes-Pereira, Ben Ouyang, Lino da Silva Ferreira, Debanjan Sarkar
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Publication number: 20220213252Abstract: Among other things, the present disclosure provides compositions and methods for an elastomeric cross-linked polyester material. Such an elastomeric cross-linked polyester material, in some embodiments, comprises a plurality of polymeric units of the general formula (-A-B-)p, wherein p is an integer greater than 1; and a plurality of urethane cross-links each of which covalently links two polymeric units to one another, which two linked polymeric unit each had at least one free hydroxyl or amino group prior to formation of the crosslink.Type: ApplicationFiled: January 11, 2022Publication date: July 7, 2022Inventors: Robert S. Langer, Jeffrey M. Karp, Maria Jose Maio Nunes-Pereira, Ben Ouyang, Lino da Silva Ferreira, Debanjan Sarkar
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Patent number: 11254781Abstract: Among other things, the present disclosure provides compositions and methods for an elastomeric cross-linked polyester material. Such an elastomeric cross-linked polyester material, in some embodiments, comprises a plurality of polymeric units of the general formula (-A-B-)p, wherein p is an integer greater than 1; and a plurality of urethane cross-links each of which covalently links two polymeric units to one another, which two linked polymeric unit each had at least one free hydroxyl or amino group prior to formation of the crosslink.Type: GrantFiled: February 25, 2021Date of Patent: February 22, 2022Assignees: Massachusetts Institute of Technology, The Brigham and Women's Hospital, Inc., Biocant-Center of Innovation and BiotechnologyInventors: Robert S. Langer, Jeffrey M. Karp, Maria Jose Maio Nunes-Pereira, Ben Ouyang, Lino da Silva Ferreira, Debanjan Sarkar
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Publication number: 20210230343Abstract: Among other things, the present disclosure provides compositions and methods for an elastomeric cross-linked polyester material. Such an elastomeric cross-linked polyester material, in some embodiments, comprises a plurality of polymeric units of the general formula (-A-B-)p, wherein p is an integer greater than 1; and a plurality of urethane cross-links each of which covalently links two polymeric units to one another, which two linked polymeric unit each had at least one free hydroxyl or amino group prior to formation of the crosslink.Type: ApplicationFiled: February 25, 2021Publication date: July 29, 2021Inventors: Robert S. Langer, Jeffrey M. Karp, Maria Jose Maio Nunes-Pereira, Ben Ouyang, Lino da Silva Ferreira, Debanjan Sarkar
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Patent number: 10982038Abstract: Among other things, the present disclosure provides compositions and methods for an elastomeric cross-linked polyester material. Such an elastomeric cross-linked polyester material, in some embodiments, comprises a plurality of polymeric units of the general formula (-A-B—)p, wherein p is an integer greater than 1; and a plurality of urethane cross-links each of which covalently links two polymeric units to one another, which two linked polymeric unit each had at least one free hydroxyl or amino group prior to formation of the crosslink.Type: GrantFiled: June 29, 2018Date of Patent: April 20, 2021Assignees: MASSACHUSETTS INSTITUTE OF TECHNOLOGY, THE BRIGHAM AND WOMEN'S HOSPITAL, INC., BIOCANT-CENTER OF INNOVATION AND BIOTECHNOLOGYInventors: Robert S. Langer, Jeffrey M. Karp, Maria Jose Maio Nunes-Pereira, Ben Ouyang, Lino da Silva Ferreira, Debanjan Sarkar
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Publication number: 20180371149Abstract: Among other things, the present disclosure provides compositions and methods for an elastomeric cross-linked polyester material. Such an elastomeric cross-linked polyester material, in sonic embodiments, comprises a plurality of polymeric units of the general formula (-A-B-)p, wherein p is an integer greater than 1; and a plurality of urethane cross-links each of which covalently links two polymeric units to one another, which two linked polymeric unit each had at least one free hydroxyl or amino group prior to formation of the crosslink.Type: ApplicationFiled: June 29, 2018Publication date: December 27, 2018Inventors: Robert S. Langer, Jeffrey M. Karp, Maria Jose Maio Nunes-Pereira, Ben Ouyang, Lino da Silva Ferreira, Debanjan Sarkar
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Patent number: 10035871Abstract: Among other things, the present disclosure provides compositions and methods for an elastomeric cross-linked polyester material. Such an elastomeric cross-linked polyester material, in some embodiments, comprises a plurality of polymeric units of the general formula (-A-B—)p, wherein p is an integer greater than 1; and a plurality of urethane cross-links each of which covalently links two polymeric units to one another, which two linked polymeric unit each had at least one free hydroxyl or amino group prior to formation of the crosslink.Type: GrantFiled: August 26, 2012Date of Patent: July 31, 2018Assignees: Massachusetts Institute of Technology, The Brigham and Women's Hospital, Inc., Biocant-Center of Innovation and BiotechnologyInventors: Robert S. Langer, Jeffrey M. Karp, Maria Jose Maio Nunes-Pereira, Ben Ouyang, Lino Da Silva Ferreira, Debanjan Sarkar
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Patent number: 9884129Abstract: A composition includes an isolated cell; at least one particle within said cell; and at least one active agent associated with the particle, wherein the active agent is capable of being released from the cell. A method includes administration of such a cell to a subject.Type: GrantFiled: January 5, 2015Date of Patent: February 6, 2018Assignee: The Brigham and Women's Hospital, Inc.Inventors: Jeffrey M. Karp, Debanjan Sarkar, Praveen Kumar Vemula
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Publication number: 20150125540Abstract: A composition includes an isolated cell; at least one particle within said cell; and at least one active agent associated with the particle, wherein the active agent is capable of being released from the cell. A method includes administration of such a cell to a subject.Type: ApplicationFiled: January 5, 2015Publication date: May 7, 2015Inventors: Jeffrey M. Karp, Debanjan Sarkar, Praveen Kumar Vemula
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Patent number: 8956863Abstract: A composition includes an isolated cell; at least one particle within said cell; and at least one active agent associated with the particle, wherein the active agent is capable of being released from the cell. A method includes administration of such a cell to a subject.Type: GrantFiled: October 15, 2010Date of Patent: February 17, 2015Assignee: The Brigham and Women's Hospital, Inc.Inventors: Jeffrey M. Karp, Debanjan Sarkar, Praveen Kumar Vemula
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Publication number: 20130231412Abstract: Among other things, the present disclosure provides compositions and methods for an elastomeric cross-linked polyester material. Such an elastomeric cross-linked polyester material, in some embodiments, comprises a plurality of polymeric units of the general formula (-A-B—)p, wherein p is an integer greater than 1; and a plurality of urethane cross-links each of which covalently links two polymeric units to one another, which two linked polymeric unit each had at least one free hydroxyl or amino group prior to formation of the crosslink.Type: ApplicationFiled: August 26, 2012Publication date: September 5, 2013Inventors: Robert S. Langer, Jeffrey M. Karp, Maria Jose Maio Nunes-Pereira, Ben Ouyang, Lino Da Silva Ferreira, Debanjan Sarkar
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Publication number: 20130040837Abstract: A composition includes an isolated cell, wherein a surface of the cell is attached to a nucleic acid that specifically binds to a non-nucleic target.Type: ApplicationFiled: December 1, 2010Publication date: February 14, 2013Applicant: BRIGHAM AND WOMEN'S HOSPITAL, INC.Inventors: Jeffrey M. Karp, Wei Li Loh, Debanjan Sarkar, Sebastian Schaefer, Weian Zhao
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Publication number: 20120263765Abstract: A composition includes an isolated cell; at least one particle within said cell; and at least one active agent associated with the particle, wherein the active agent is capable of being released from the cell. A method includes administration of such a cell to a subject.Type: ApplicationFiled: October 15, 2010Publication date: October 18, 2012Applicant: THE BRIGHAM AND WOMEN'S HOSPITAL, INC.Inventors: Jeffrey M. Karp, Debanjan Sarkar, Praveen Kumar Vemula
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Publication number: 20110206740Abstract: The present invention is directed to methods and compositions for engineering the surface of a cell, wherein a targeting moiety and/or a particle are attached to the cell membrane. The particle can further comprise a therapeutic agent for drug delivery. The compositions disclosed herein are useful in the treatment of diseased or damaged tissue by targeting cells for the purpose of tissue regeneration, drug delivery or a combination of both.Type: ApplicationFiled: April 29, 2009Publication date: August 25, 2011Inventors: Jeffrey M. Karp, Debanjan Sarkar, Praveen Kumar Vemula
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Publication number: 20100291219Abstract: The invention provides compositions and methods for harvesting and enriching cells such as connective tissue progenitors cells using stirred bioreactors, and in some embodiments fibrin microcarriers.Type: ApplicationFiled: June 20, 2008Publication date: November 18, 2010Inventors: Jeffrey M. Karp, Robert S. Langer, Cecilia Graneli, Debanjan Sarkar
