Abstract: According to one embodiment, an absorbent article includes a moisture-impervious outer layer, an inner layer substantially co-extensive with the outer layer, and an absorbent layer interposed between the outer layer and the inner layer. The inner layer is treated with at least one antimicrobial booster. The absorbent layer is treated with at least one antimicrobial agent.

Abstract: According to one embodiment, an absorbent article includes a moisture-impervious outer layer, an inner layer substantially co-extensive with the outer layer, and an absorbent layer interposed between the outer layer and the inner layer. The inner layer is treated with at least one antimicrobial booster. The absorbent layer is treated with at least one antimicrobial agent.

Abstract: A wound management system can comprise a surgically acceptable adhesive disposed over a wound and a surgically acceptable film repositionably disposed over the surgically acceptable adhesive, and methods of managing a wound involving the same.

Abstract: A wound dressing makes use of a polysaccharide, such as Manuka honey, in combination with collagen in order to suppress the efficacy of matrix metalloproteinases enzymes (“MMPs”) present in chronic wounds. The mixture is applied to an absorbent surface that is designed to absorb the mixed polysaccharide only partially.

Abstract: A wound dressing makes use of polysaccharides, including the formation of a range of variable viscosity mixtures that use a solid polysaccharide such as medical grade cane sugar and a liquid polysaccharide such as honey, both of which have inherent beneficial properties for wound healing. The mixture is applied to an absorbent surface that is designed to absorb the mixed polysaccharide only partially.

Abstract: A method (400) of manufacturing a wound dressing is disclosed that includes obtaining alginate fibers (108) and the step (404) of spraying either the alginate fibers (108) or a dressing or dressing layer (610) of the alginate fibers with an aqueous solution (801) comprising a polysaccharide, which can be carboxymethylcellulose. The step of spraying can occur while the alginate fibers, dressing, or dressing layer are wet. A step (405) of flash drying can follow to remove the solute of the aqueous solution to leave the polysaccharide along the alginate. The step of spraying can be selective, such that only portions of the dressing layer include the polysaccharide.

Abstract: According to one embodiment, an absorbent article includes a moisture-impervious outer layer, an inner layer substantially co-extensive with the outer layer, and an absorbent layer interposed between the outer layer and the inner layer. The inner layer is treated with at one least substance including dimethicone and/or at least one antimicrobial booster. The absorbent layer is treated with at least one antimicrobial agent.

Abstract: A composite wound dressing comprising an absorbent portion coupled to the vapor permeable backing with a first adhesive and a wound contact portion having a first portion coupled to the absorbent portion with a second adhesive, and the wound contact portion having a second portion coupled to the vapor permeable backing with the first adhesive is disclosed. Further a skin securement portion coupled to the backing portion with the first adhesive, the skin securement portion including a semi-self adherent adhesive, and a void having a first size, wherein at least a portion of absorbent is accessible through the void. The wound contact portion has a size greater than the first size of the void.

Abstract: According to one embodiment, an absorbent article includes a moisture-impervious outer layer, an inner layer substantially co-extensive with the outer layer, and an absorbent layer interposed between the outer layer and the inner layer. The inner layer is treated with at least one antimicrobial booster. The absorbent layer is treated with at least one antimicrobial agent.

Abstract: A polymeric composition capable of releasing nitric oxide comprises a polysaccharide including a nitric oxide-releasing N.sub.2 O.sub.2.sup.- functional group bound to the polymer; pharmaceutical compositions including the polymeric composition; and methods for treating biological disorders in which dosage with nitric oxide is beneficial. The compositions can be used as and/or incorporated into implants, injectables, condoms, prosthesis coatings, patches, and the like for use in a wide variety of medical applications.

Abstract: A water swellable and hydrolytically labile (and therefore potentially biodegradable) non-toxic crosslinked polysaccharide in microsphere or bead form. The crosslinked polysaccharide comprises polysaccharide chains and crosslinking groups which are imidocarbonate groups, carbonate groups or a mixture thereof. The microspheres are predominantly in the range of about 1 micron to about 100 microns in diameter, preferably about 2-50 microns. The crosslinked polysaccharide polymer, which is preferably a crosslinked dextran, is formed by treating a water soluble non-crosslinked polysaccharide with a cyanogen halide (preferably cyanogen bromide) in an aqueous alkaline medium which is the disperse phase of a water-in-oil dispersion. The microspheres are useful in the treatment of wounds, in particular as an absorptive agent for wound exudates. The microspheres may be formed into a wound dressing which includes a blend of the microspheres and a hydrophobic adhesive matrix material on a waterproof backing sheet.

Abstract: An adhesive composition suitable for wound dressing and other medical applications comprising a mixture of polyisobutylene and a rubber polymer selected from the group consisting of random styrene butadiene rubber (SBR) and halobutyl rubber so as to form a rubbery elastomer base matrix, and at least one hydrocolloid. The addition of the SBR or halobutyl rubber to the elastomer base offsets the possible degradation of the polyisobutylene upon sterilization, and therefore, helps to maintain the integrity of the composition. Water soluble hydrocolloid gums and water swellable cohesive strengthening agents are dispersed within the base matrix and may carry a pharmaceutical agent to be dispensed directly to a wound site.