Abstract: A nanocomposite includes one or more graphene-based materials (GMs), a nitrogen-containing polymer (an N-polymer), and elemental sulfur (S). The nanocomposite is suitable for use as a stable, high capacity electrode for rechargeable batteries such as lithium-sulfur (Li—S) batteries. Example methods of fabricating a nanocomposite include the addition of an N-polymer to a dispersion (e.g., an aqueous dispersion) or slurry of GMs mixed with a sulfur sol. The N-polymer can interact strongly with the GMs to form a cross-linked network. In one embodiment, hydrothermal treatment of the aqueous dispersion or slurry is used to melt the sulfur such that it becomes distributed within the network formed by the GMs and the N-polymer. The resulting nanocomposite material can then be processed through the addition of one or more other binders and/or solvents, and formed into a final electrode.

Abstract: A system and related methods for providing greater security and control over access to classified files and documents and other forms of sensitive information based upon a multi-user permission strategy centering on organizational structure. Based on the sensitivity or classification of the information being requested by a user, approvers are selected dynamically based on the work environment (e.g., mobility, use of the computing device seeking access, access policy, and the like). The selected sets of approvers are non-repetitive in nature, making it very hard to guess which approvers will be selected for a particular request.

Abstract: Systems and related methods for providing greater security and control over access to protected or classified resources, files and documents and other forms of sensitive information based upon an initial adaptive selection of multiple modalities for authentication in different operating environments, with subsequent multi-user permission strategy centering on organizational structure. The system calculates trustworthiness values of different authentication factors under various environmental settings, and combines a trust-based adaptive, robust and scalable software-hardware framework for the selection of authentication factors for continuous and triggered authentication with optimal algorithms to determine the security parameters of each of the authentication factors. A subset of authentication factors thus are determined for application at triggering events on-the-fly, thereby leaving no exploitable a priori pattern or clue for hackers to exploit.

Abstract: A system and related methods for providing greater security and control over access to classified files and documents and other forms of sensitive information based upon a multi-user, multi-modality permission strategy centering on organizational structure, thereby making authentication strategy unpredictable so to significantly reduce the risk of exploitation. Based on the sensitivity or classification of the information being requested by a user, approvers are selected dynamically based on the work environment, e.g., mobility, use of the computing device seeking access, authentication factors under applicable environmental settings, access policy, and the like.

Abstract: Systems and related methods for providing greater security and control over access to protected or classified resources, files and documents and other forms of sensitive information based upon an initial adaptive selection of multiple modalities for authentication in different operating environments, with subsequent multi-user permission strategy centering on organizational structure. The system calculates trustworthiness values of different authentication factors under various environmental settings, and combines a trust-based adaptive, robust and scalable software-hardware framework for the selection of authentication factors for continuous and triggered authentication with optimal algorithms to determine the security parameters of each of the authentication factors. A subset of authentication factors thus are determined for application at triggering events on-the-fly, thereby leaving no exploitable a priori pattern or clue for hackers to exploit.

Abstract: A system and related methods for providing greater security and control over access to classified files and documents and other forms of sensitive information based upon a multi-user permission strategy centering on organizational structure. Based on the sensitivity or classification of the information being requested by a user, approvers are selected dynamically based on the work environment (e.g., mobility, use of the computing device seeking access, access policy, and the like). The selected sets of approvers are non-repetitive in nature, making it very hard to guess which approvers will be selected for a particular request.

Abstract: A nanocomposite includes one or more graphene-based materials (GMs), a nitrogen-containing polymer (an N-polymer), and elemental sulfur (S). The nanocomposite is suitable for use as a stable, high capacity electrode for rechargeable batteries such as lithium-sulfur (Li—S) batteries. Example methods of fabricating a nanocomposite include the addition of an N-polymer to a dispersion (e.g., an aqueous dispersion) or slurry of GMs mixed with a sulfur sol. The N-polymer can interact strongly with the GMs to form a cross-linked network. In one embodiment, hydrothermal treatment of the aqueous dispersion or slurry is used to melt the sulfur such that it becomes distributed within the network formed by the GMs and the N-polymer. The resulting nanocomposite material can then be processed through the addition of one or more other binders and/or solvents, and formed into a final electrode.

Abstract: A system and related methods for providing greater security and control over access to classified files and documents and other forms of sensitive information based upon a multi-user, multi-modality permission strategy centering on organizational structure, thereby making authentication strategy unpredictable so to significantly reduce the risk of exploitation. Based on the sensitivity or classification of the information being requested by a user, approvers are selected dynamically based on the work environment, e.g., mobility, use of the computing device seeking access, authentication factors under applicable environmental settings, access policy, and the like.

Abstract: Disclosed herein are pyrido[2,3-d]pyrimidines having the structure wherein R1, and R2 are independently selected from nitro and amino; wherein R3 is selected from alkyl (C1-C10) and cycloalkyl (C3-C8); wherein R4 is selected from hydrogen, benzyl, alkyl (C1-C10), cycloalkyl (C3-C8), arylalkyl (C4-C8), and aryl (C3-C8); wherein R5 and R6 are independently selected from hydrogen, benzyl, alkyl (C1-C10), cycloalkyl (C3-C8), arylalkyl (C4-C14), and aryl (C3-C8); wherein R3 and R4 may form a ring; wherein R5 and R6 may form a ring or a heterocyclic structure; and wherein R5 and R6 are independently unsubstituted or substituted, wherein each substituent is independently selected from halogen, amino, alkyl (C1-C6), haloalkyl (C1-C6), alkoxy(C1-C6), alkylenedioxy, aryl, heteroaryl, and cycloalkyl (C3-C8). Also disclosed are methods for the preparation of compounds of Formula I and various intermediates. These compounds are useful as NAD+-dependent DNA ligase inhibitors.

Abstract: The present invention is directed to a novel dopamine receptor ligands of the formula: pharmaceutical formulations of such compounds, and a method using such compounds for treating a patient suffering from dopamine-related dysfunction of the central or peripheral nervous system.

Abstract: The present invention is directed to a novel dopamine receptor ligands of the formula: ##STR1## pharmaceutical formulations of such compounds, and a method using such compounds for treating a patient suffering from dopamine-related dysfunction of the central or peripheral nervous system.