Patents by Inventor Debbie Law

Debbie Law has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions against cancer antigen LIV-1 and uses thereof
    Patent number: 8906342
    Abstract: Described herein are methods and compositions that can be used for diagnosis and treatment of cancer.
    Type: Grant
    Filed: October 14, 2013
    Date of Patent: December 9, 2014
    Assignee: Abbvie Biotherapeutics Inc.
    Inventors: Debbie Law, Kurt Gish
  • COMPOSITIONS AGAINST CANCER ANTIGEN LIV-1 AND USES THEREOF
    Publication number: 20140037540
    Abstract: Described herein are methods and compositions that can be used for diagnosis and treatment of cancer.
    Type: Application
    Filed: October 14, 2013
    Publication date: February 6, 2014
    Applicant: ABBVIE BIOTHERAPEUTICS INC.
    Inventors: DEBBIE LAW, KURT GISH
  • Compositions against cancer antigen LIV-1 and uses thereof
    Patent number: 8591863
    Abstract: Described herein are methods and compositions that can be used for diagnosis and treatment of cancer.
    Type: Grant
    Filed: June 20, 2012
    Date of Patent: November 26, 2013
    Assignee: Abbvie Biotherapeutics Inc.
    Inventors: Debbie Law, Kurt Gish
  • COMPOSITIONS AGAINST CANCER ANTIGEN LIV-1 AND USES THEREOF
    Publication number: 20120328513
    Abstract: Described herein are methods and compositions that can be used for diagnosis and treatment of cancer.
    Type: Application
    Filed: June 20, 2012
    Publication date: December 27, 2012
    Applicant: Abbott Biotherapeutics Corp.
    Inventors: Debbie Law, Kurt Gish
  • Antibodies against cancer antigen TMEFF2 and uses thereof
    Patent number: 8257708
    Abstract: The invention relates to the identification and generation of antibodies that bind to TMEFF2 proteins which are involved in cancer. Further, the invention provides for the use of these antibodies in the treatment of cancer.
    Type: Grant
    Filed: September 28, 2010
    Date of Patent: September 4, 2012
    Assignee: Abbott Biotherapeutics Corp.
    Inventors: Vinay Bhaskar, Agustin De La Calle, Debbie Law, Ingrid Caras, Vanitha Ramakrishnan, Richard Murray, Daniel Afar, David Powers
  • Antibodies Against Cancer Antigen TMEFF2 and Uses Thereof
    Publication number: 20110038864
    Abstract: Described herein are methods and compositions that can be used for diagnosis and treatment of cancer.
    Type: Application
    Filed: September 28, 2010
    Publication date: February 17, 2011
    Applicant: Facet Biotech Corporation
    Inventors: Vinay BHASKAR, Agustin De La Calle, Debbie Law, Ingrid Caras, Vanitha Ramakrishnan, Richard Murray, Daniel Afar, David Powers
  • Use of Anti-Alpha5Beta1 Antibodies to Inhibit Cancer Cell Proliferation
    Publication number: 20100291111
    Abstract: The present invention provides methods for direct killing of cancer cells using anti-?5?1 antibodies. Generally, the method comprises contacting a cancer cell that expresses ?5?1 on its surface with an anti-?5?1 antibody, and thereby inducing the death of the cancer cell. The methods of the invention may be employed at an early stage of cancer development in a patient to prevent tumor establishment. In addition, the methods may be used to treat previously formed tumors especially in cancer that have not proven susceptible to anti-angiogenesis therapy. The methods may be employed as a combination therapy of anti-?5?1 antibodies together with cancer chemotherapeutic agents or other molecular-based cancer therapeutic agents.
    Type: Application
    Filed: December 18, 2009
    Publication date: November 18, 2010
    Applicant: FACET BIOTECH
    Inventors: VANITHA RAMAKRISHNAN, VINAY BHASKAR, SUN HO, RICHARD MURRAY, DEBBIE LAW
  • Antibodies against cancer antigen TMEFF2 and uses thereof
    Patent number: 7824678
    Abstract: Described herein are methods and compositions that can be used for diagnosis and treatment of cancer.
    Type: Grant
    Filed: August 10, 2007
    Date of Patent: November 2, 2010
    Assignee: Facet Biotech Corporation
    Inventors: Vinay Bhaskar, Agustin De La Calle, Debbie Law, Ingrid Caras, Vanitha Ramakrishnan, Richard Murray, Daniel Afar, David Powers
  • Antibodies against GPR64 and uses thereof
    Patent number: 7807163
    Abstract: GPR64 antibody compositions are provided. These antibodies may be used for diagnosis or treatment of cancer, especially ovarian cancer, Ewing's sarcoma, uterine cancer, and other GPR64 expressing tumor types.
    Type: Grant
    Filed: September 3, 2008
    Date of Patent: October 5, 2010
    Assignee: Facet Biotech Corporation
    Inventors: Debbie Law, Qi Wang, Robert DuBridge, Vinay Bhaskar
  • Antibodies against cancer antigen TMEFF2 and uses thereof
    Patent number: 7785816
    Abstract: Described herein are methods and compositions that can be used for diagnosis and treatment of cancer.
    Type: Grant
    Filed: August 10, 2007
    Date of Patent: August 31, 2010
    Assignee: Facet Biotech Corporation
    Inventors: Vinay Bhaskar, Agustin de la Calle, Debbie Law, Ingrid Caras, Vanitha Ramakrishnan, Richard Murray, Daniel Afar, David Powers
  • Compositions Against Cancer Antigen LIV-1 and Uses Thereof
    Publication number: 20100074841
    Abstract: Described herein are methods and compositions that can be used for diagnosis and treatment of cancer.
    Type: Application
    Filed: November 19, 2009
    Publication date: March 25, 2010
    Applicant: FACET BIOTECH CORPORATION
    Inventors: Debbie Law, Kurt C. Gish, Richard Murray, Patricia Culp
  • Antibodies against cancer antigen TMEFF2 and uses thereof
    Patent number: 7674883
    Abstract: Described herein are methods and compositions that can be used for diagnosis and treatment of cancer.
    Type: Grant
    Filed: September 13, 2007
    Date of Patent: March 9, 2010
    Assignee: Facet Biotech Corporation
    Inventors: Vinay Bhaskar, Agustin de la Calle, Debbie Law, Ingrid Caras, Vanitha Ramakrishnan, Richard Murray, Daniel Afar, David Powers
  • Use of anti-?5?1 antibodies to inhibit cancer cell proliferation
    Patent number: 7662384
    Abstract: The present invention provides methods for direct killing of cancer cells using anti-?5?1 antibodies. Generally, the method comprises contacting a cancer cell that expresses ?5?1 on its surface with an anti-?5?1 antibody, and thereby inducing the death of the cancer cell. The methods of the invention may be employed at an early stage of cancer development in a patient to prevent tumor establishment. In addition, the methods may be used to treat previously formed tumors especially in cancer that have not proven susceptible to anti-angiogenesis therapy. The methods may be employed as a combination therapy of anti-?5?1 antibodies together with cancer chemotherapeutic agents or other molecular-based cancer therapeutic agents.
    Type: Grant
    Filed: March 24, 2005
    Date of Patent: February 16, 2010
    Assignee: Facet Biotech Corporation
    Inventors: Vanitha Ramakrishnan, Vinay Bhaskar, Sun Ho, Richard Murray, Debbie Law
  • THERAPEUTIC USE OF ANTI-CS1 ANTIBODIES
    Publication number: 20090246852
    Abstract: The present invention is directed to antagonists of CS1 that bind to and neutralize at least one biological activity of CS1. The invention also includes a pharmaceutical composition comprising such antibodies or antigen-binding fragments thereof. The present invention also provides for a method of preventing or treating disease states, including autoimmune disorders and cancer, in a subject in need thereof, comprising administering into said subject an effective amount of such antagonists.
    Type: Application
    Filed: March 3, 2009
    Publication date: October 1, 2009
    Applicant: FACET BIOTECH CORPORATION
    Inventors: Marna Williams, J. Yun Tso, Nicholas F. Landolfi, David B. Powers, Robert B. DuBridge, Debbie Law, Gao Liu
  • Antibodies against GPR64 and uses thereof
    Patent number: 7547544
    Abstract: GPR64 antibody compositions are provided. These antibodies may be used for diagnosis or treatment of cancer, especially ovarian cancer, Ewing's sarcoma, uterine cancer, and other GPR64 expressing tumor types.
    Type: Grant
    Filed: September 7, 2007
    Date of Patent: June 16, 2009
    Assignee: Facet Biotech Corporation
    Inventors: Debbie Law, Qi Wang, Robert DuBridge, Vinay Bhaskar
  • ANTIBODIES AGAINST GPR64 AND USES THEREOF
    Publication number: 20090117036
    Abstract: GPR64 antibody compositions are provided. These antibodies may be used for diagnosis or treatment of cancer, especially ovarian cancer, Ewing's sarcoma, uterine cancer, and other GPR64 expressing tumor types.
    Type: Application
    Filed: September 3, 2008
    Publication date: May 7, 2009
    Inventors: Debbie Law, Qi Wang, Robert BuBridge, Vinay Bhaskar
  • Anti-LFL2 Antibodies for the Diagnosis, Prognosis and Treatment of Cancer
    Publication number: 20080260740
    Abstract: Particular anti-LFL2 antibody compositions are provided herein. These antibodies may be used for diagnosis, prognosis, therapeutic monitoring and treatment of cancer, especially breast cancer, head/neck cancer, lung cancer, ovarian cancer, stomach cancer and pancreatic cancer. Furthermore, anti-LFL2 antibodies are provided herein which target the LFL2 stump remaining after proteolytic cleavage of the extracellular domain of LFL2. Additionally, anti-LFL2 antibodies are provided herein which target the stroma surrounding cancer tumors, wherein said stroma-targeting anti-LFL2 antibodies disrupt the integrity of the stroma surrounding the cancer tumor, and also make the stroma more permeable to chemotherapeutic agents and other molecular drug agents that target tumor cells.
    Type: Application
    Filed: June 12, 2008
    Publication date: October 23, 2008
    Applicant: PDL BIOPHARMA, INC.
    Inventors: Yongke ZHANG, Vanitha RAMAKRISHNAN, Debbie LAW
  • ANTIBODIES AGAINST CANCER ANTIGEN TMEFF2 AND USES THEREOF
    Publication number: 20080175846
    Abstract: Described herein are methods and compositions that can be used for diagnosis and treatment of cancer.
    Type: Application
    Filed: September 13, 2007
    Publication date: July 24, 2008
    Applicant: PDL BIOPHARMA, INC.
    Inventors: Vinay Bhaskar, Agustin de la Calle, Debbie Law, Ingrid Caras, Vanitha Ramakrishnan, Richard Murray, Daniel Afar, David Powers
  • Compositions Against Cancer Antigen LIV-1 and Uses Thereof
    Publication number: 20080175839
    Abstract: Described herein are methods and compositions that can be used for diagnosis and treatment of cancer.
    Type: Application
    Filed: December 21, 2007
    Publication date: July 24, 2008
    Applicant: Protein Design Labs, Inc.
    Inventors: Debbie Law, Kurt C. Gish, Richard Murray, Patricia Culp
  • Compositions Against Cancer Antigen Liv-1 and Uses Thereof
    Publication number: 20080171039
    Abstract: Described herein are methods and compositions that can be used for diagnosis and treatment of cancer.
    Type: Application
    Filed: December 21, 2007
    Publication date: July 17, 2008
    Applicant: Protein Design Labs, Inc.
    Inventors: Debbie Law, Kurt C. Gish, Richard Murray, Patricia Culp