Patents by Inventor Debbie Mantzaris
Debbie Mantzaris has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 9447467Abstract: The present invention relates to a method of enriching fetal nuclei from a sample. Enriched fetal nuclei can be used in a variety of procedures including, detection of a trait of interest such as a disease trait, or a genetic predisposition thereto, gender typing and parentage testing.Type: GrantFiled: April 20, 2010Date of Patent: September 20, 2016Assignee: GENETIC TECHNOLOGIES LIMITEDInventors: Richard Allman, Debbie Mantzaris, Eduardo Vom, Craig Matthew Lewis
-
Patent number: 9078642Abstract: A sampling device adapted for transcervical sampling of biological materials from a pregnant patient comprising: an elongate insertion tube (4) having a first end (5) adapted for insertion through the external orifice (external os) of said patient's cervix and a second end (6) including a handle means (7) for manipulating said tube; a measuring means for determining the position of said first end of said tube within said cervix, wherein said first end (5) includes a sampling head (9, 14) adapted to collect biological material including cells, mucus and biological fluids, and wherein said measuring means is adapted to determine the extent of insertion and transcervical position of said first end to optimize the transcervical sampling site.Type: GrantFiled: January 25, 2010Date of Patent: July 14, 2015Assignee: GENETIC TECHNOLOGIES LIMITEDInventors: Eduardo Vom, Craig Lewis, Richard Allman, Debbie Mantzaris
-
Patent number: 8827923Abstract: A sampling device adapted for transcervical sampling of biological materials from a pregnant patient comprising: an elongate insertion tube (4) having a first end (5) adapted for insertion through the external orifice (external os) of said patient's cervix and a second end (6) including a handle means (7) for manipulating said tube; a measuring means for determining the position of said first end of said tube within said cervix, wherein said first end (5) includes a sampling head (9, 14) adapted to collect biological material including cells, mucus and biological fluids, and wherein said measuring means is adapted to determine the extent of insertion and transcervical position of said first end to optimise the transcervical sampling site.Type: GrantFiled: October 29, 2013Date of Patent: September 9, 2014Assignee: Genetic Technologies LimitedInventors: Eduardo Vom, Craig Lewis, Richard Allman, Debbie Mantzaris
-
Patent number: 8734364Abstract: Embodiments relate generally to a sampling device adapted for sampling of biological materials from a subject and methods of use or manufacture of such devices, as well as diagnostic methods employing such devices and kits including such devices. The sampling device may comprise: an outer tube; an elongate insertion member having a first end and a second end, wherein the first end is distal of the second end, the insertion member being received in and sized to be movable through the outer tube; a coupling portion disposed at the first end of the insertion member; and a sampling portion coupled to the coupling portion and configured to collect the biological materials. The coupling portion is separable from the insertion member.Type: GrantFiled: November 7, 2013Date of Patent: May 27, 2014Assignee: Genetic Technologies LimitedInventors: Debbie Mantzaris, Nicola Charlotte Andrews, Denis Greco, David Jonathan Sparling
-
Publication number: 20140073989Abstract: A sampling device adapted for transcervical sampling of biological materials from a pregnant patient comprising: an elongate insertion tube (4) having a first end (5) adapted for insertion through the external orifice (external os) of said patient's cervix and a second end (6) including a handle means (7) for manipulating said tube; a measuring means for determining the position of said first end of said tube within said cervix, wherein said first end (5) includes a sampling head (9, 14) adapted to collect biological material including cells, mucus and biological fluids, and wherein said measuring means is adapted to determine the extent of insertion and transcervical position of said first end to optimise the transcervical sampling site.Type: ApplicationFiled: October 29, 2013Publication date: March 13, 2014Applicant: GENETIC TECHNOLOGIES, LTD.Inventors: Eduardo Vom, Craig Lewis, Richard Allman, Debbie Mantzaris
-
Publication number: 20120329667Abstract: This application relates to methods for enriching DNA from a first cell type from a sample comprising DNA from the first cell type and DNA from a second cell type, wherein the first cell type methylates DNA to a lesser extent than the second cell type. DNA is enriched by, selecting for fragments by size after digestion of the sample with a methylation-sensitive restriction enzyme. Cell types of interest include fetal cells and cancerous cells. The enriched DNA can be used for a variety of procedures including, detection of a trait of interest such as a disease trait, or a genetic predisposition thereto, gender typing and parentage testing.Type: ApplicationFiled: October 13, 2010Publication date: December 27, 2012Applicant: GENETIC TECHNOLOGIES LIMITEDInventors: Richard Allman, Eduardo Vom, Craig Matthew Lewis, Debbie Mantzaris, Stuart Cantsilieris
-
Publication number: 20120315633Abstract: The present invention relates to a method of enriching free fetal nucleic acids from a cervical sample. The enriched fetal nucleic acids can be used in a variety of procedures including, detection of a trait of interest such as a disease trait, or a genetic predisposition thereto, gender typing and parentage testing.Type: ApplicationFiled: December 22, 2010Publication date: December 13, 2012Applicant: GENETIC TECHNOLOGIES LIMITEDInventors: Debbie Mantzaris, Richard Allman, Stuart Cantsilieris, Eduardo Vom, Maria Luisa Ashdown
-
Publication number: 20120149014Abstract: The present invention relates to a method of enriching fetal nuclei from a sample. Enriched fetal nuclei can be used in a variety of procedures including, detection of a trait of interest such as a disease trait, or a genetic predisposition thereto, gender typing and parentage testing.Type: ApplicationFiled: April 20, 2010Publication date: June 14, 2012Applicant: GENETIC TECHNOLOGIES LIMITEDInventors: Richard Allman, Debbie Mantzaris, Eduardo Vom, Craig Matthew Lewis
-
Publication number: 20120122091Abstract: A sampling device adapted for transcervical sampling of biological materials from a pregnant patient comprising: an elongate insertion tube (4) having a first end (5) adapted for insertion through the external orifice (external os) of said patient's cervix and a second end (6) including a handle means (7) for manipulating said tube; a measuring means for determining the position of said first end of said tube within said cervix, wherein said first end (5) includes a sampling head (9, 14) adapted to collect biological material including cells, mucus and biological fluids, and wherein said measuring means is adapted to determine the extent of insertion and transcervical position of said first end to optimise the transcervical sampling site.Type: ApplicationFiled: January 25, 2010Publication date: May 17, 2012Applicant: GENETIC TECHNOLOGIES LIMITEDInventors: Eduardo Vom, Craig Lewis, Richard Allman, Debbie Mantzaris
-
Publication number: 20110027795Abstract: The present invention relates to methods of processing and/or enriching cells from a pregnant female. More particularly the invention provides methods for processing and/or enriching fetal cells from a pregnant female. The enriched fetal cells can be used in a variety of procedures including, detection of a trait of interest such as a disease trait, or a genetic predisposition thereto, gender typing and parentage testing.Type: ApplicationFiled: February 18, 2009Publication date: February 3, 2011Applicant: GENETIC TECHNOLOGIES LIMITEDInventors: Debbie Mantzaris, Richard Allman