Patents by Inventor Debbie Watson

Debbie Watson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Genetic transformation of bifidobacteria
    Patent number: 10184127
    Abstract: The present invention concerns a method for genetically transforming a Bifidobacterium strain comprising a step of methylation of a shuttle vector in an E. coli or a Gram-positive bacterium strain by two type II DNA methyltransferases from a Bifidobacterium: a methyltransferase enzyme that methylates the adenine base at position 4 of the nucleotide sequence RTCAGG and a methyltransferase enzyme that methylates the cytosine base at position 4 of the nucleotide sequence GGWCC. The present invention also concerns genetic tools and culture media useful for carrying out said method.
    Type: Grant
    Filed: December 2, 2013
    Date of Patent: January 22, 2019
    Assignees: Compagnie Gervais Danone, University College Cork—National University of Ireland, Cork
    Inventors: Douwe van Sinderen, Mary O'Connell Motherway, Debbie Watson, Tamara Smokvina, Peggy Garault
  • Genetic Transformation of Bifidobacteria
    Publication number: 20160304885
    Abstract: The present invention concerns a method for genetically transforming a Bifidobacterium strain comprising a step of methylation of a shuttle vector in an E. coli or a Gram-positive bacterium strain by two type II DNA methyltransferases from a Bifidobacterium: a methyltransferase enzyme that methylates the adenine base at position 4 of the nucleotide sequence RTCAGG and a methyltransferase enzyme that methylates the cytosine base at position 4 of the nucleotide sequence GGWCC. The present invention also concerns genetic tools and culture media useful for carrying out said method.
    Type: Application
    Filed: December 2, 2013
    Publication date: October 20, 2016
    Applicants: Compagnie Gervais Danone, University College Cork - National University of Ireland, Cork
    Inventors: Douwe van Sinderen, Mary O'Connell Motherway, Debbie Watson, Tamara Smokvina, Peggy Garault