Abstract: Provided herein are methods of treating a subject having a disease or disorder associated with a PAH gene mutation. The methods generally comprise administering to the subject a therapeutically effective does of a recombinant adeno-associated virus (rAAV) that can express a phenylalanine hydroxylase (PAH) polypeptide in a cell and thereby restore PAH gene function in the subject.

Abstract: A method and apparatus is disclosed for magnetic treatment of fluids by concentrating magnetic fields on the fluids. One embodiment of the invention generally comprises a length of a flexible magnet, with an adhesive backing, wrapped 1 or more times around the outside surface of a conduit through which a fluid is passed. In an alternate embodiment a length of a flexible magnet, with an adhesive backing, is wrapped 1 or more times against the inside surface of a conduit through which a fluid is passed. The flexible magnets have various magnetic pole arrangements and various methods for holding them in place.

Abstract: Disclosed is an improved electrolytic cell 10 for the generation of low cost halogen biocidally active agent from an aqueous solution having a low halogen salt content for the use in the treatment of swimming pools and spas or other liquid effluents, especially those the fresh water swimming pools or spas. The electrolytic cell is used in line with pumps generally associated with the distribution of waters for swimming pools, spas or other facilities. The electrolytic cell has electrodes 11 made of a noble metal that are not directly in the path of the flow of the liquid.

Abstract: A stroller having wide wheels for use on soft sand. A forward wheel is mounted midline supported by a forward frame portion that is hingedly connected to a rear frame portion on which are mounted spaced apart rear wheels so that another stroller's forward wheel will nest therebetween. The hinge connecting the frame portions enables folding them to be parallel to one another and unfolding to lie in a common plane but prevents rotation beyond that plane. A vertical strut hinged to the rear of the rear portion is attached to a diagonal strut hinged to the rear of the forward frame portion to secure the use position, and a handle is hinged to the diagonal strut. The various components fold to lie parallel to one another in a compact storage position. A fabric or mesh seat is mounted on the diagonal strut and a footrest on the forward frame portion.