Abstract: A wound dressing product that includes a substrate layer having an upper surface and a lower surface; a tacky silicone coating composition present on the upper surface and on the lower surface; and upper and lower release sheets covering the substrate and the tacky silicone coating composition on the upper and lower surfaces, respectively, and adhered to the surfaces by the tacky silicone coating composition, wherein the upper surface is less tacky than the lower surface whereby the upper release sheet can be removed from the upper surface more readily than the lower release sheet can be removed from the lower surface. Also provided are methods for making such dressings.

Abstract: A wound dressing comprising: a water-absorbent fabric comprising at least about 10 wt. % of hydrogel-forming absorbent fibers based on the dry weight of the fabric; and an adhesion-resistant, water-permeable wound contacting surface textile layer that is substantially continuously bonded to at least one surface of said fabric. The surface textile layer may be formed by surface treatment of the fabric, or by bonding a suitable textile web to the surface of the fabric.

Abstract: Described herein is a wound dressing comprising: a composite island configured to collectively exhibit substantially elastic recovery under wound treatment conditions and comprising a foam layer and an absorbent layer coupled to the foam layer, the foam layer exhibiting substantially elastic recovery under wound treatment conditions and the absorbent layer not exhibiting substantially elastic recovery under wound treatment conditions; a backing layer having a margin that extends beyond the composite island; and an adherent layer disposed on at least the margin of the backing layer. In addition, described herein is a method of eliminating, minimizing, or reducing edema for a wound surrounded by tissue, by positioning the wound dressing over the wound, optionally such that at least a portion of the adherent layer contacts the tissue.

Abstract: A method of making a wound dressing comprising the steps of: providing an apertured substrate layer; coating the substrate layer with a fluid silicone prepolymer composition; thermally partially curing said silicone prepolymer composition to form a partially cured silicone coating on the substrate; laminating the coated substrate layer to a base layer to form a laminate having said partially cured silicone coating in contact with a surface of the base layer; followed by exposing the laminate to ionizing radiation, to further cure the partially cured silicone coating and to bond the silicone coating to said surface of the base layer. The radiation cure results in strong bonding between the siliconized substrate and incompatible base layers such as polyurethane foams. Also provided are wound dressings obtainable by the process of the invention.

Abstract: A method of making a wound dressing comprising the steps of: providing an apertured substrate layer; coating the substrate layer with a fluid silicone prepolymer composition; thermally partially curing said silicone prepolymer composition to form a partially cured silicone coating on the substrate; laminating the coated substrate layer to a base layer to form a laminate having said partially cured silicone coating in contact with a surface of the base layer; followed by exposing the laminate to ionizing radiation, to further cure the partially cured silicone coating and to bond the silicone coating to said surface of the base layer. The radiation cure results in strong bonding between the siliconized substrate and incompatible base layers such as polyurethane foams. Also provided are wound dressings obtainable by the process of the invention.

Abstract: A method of applying a patterned coating of a silicone adhesive to a substrate sheet, comprising the steps of pattern coating a silicone precursor composition onto the substrate, followed by thermally curing the precursor composition coated on the substrate. The precursor composition is a viscous fluid, and the pattern coating is performed by suitably modified block printing, intaglio printing or screen printing methods. Also provided are coated substrates obtainable by the methods of the invention, and wound dressings comprising such coated substrates.

Abstract: A wound dressing product that includes a substrate layer having an upper surface and a lower surface; a tacky silicone coating composition present on the upper surface and on the lower surface; and upper and lower release sheets covering the substrate and the tacky silicone coating composition on the upper and lower surfaces, respectively, and adhered to the surfaces by the tacky silicone coating composition, wherein the upper surface is less tacky than the lower surface whereby the upper release sheet can be removed from the upper surface more readily than the lower release sheet can be removed from the lower surface. Also provided are methods for making such dressings.

Abstract: A method of applying a patterned coating of a silicone adhesive to a substrate sheet, comprising the steps of pattern coating a silicone precursor composition onto the substrate, followed by thermally curing the precursor composition coated on the substrate. The precursor composition is a viscous fluid, and the pattern coating is performed by suitably modified block printing, intaglio printing or screen printing methods. Also provided are coated substrates obtainable by the methods of the invention, and wound dressings comprising such coated substrates.

Abstract: A wound dressing product that includes a substrate layer having an upper surface and a lower surface; a tacky silicone coating composition present on the upper surface and on the lower surface; and upper and lower release sheets covering the substrate and the tacky silicone coating composition on the upper and lower surfaces, respectively, and adhered to the surfaces by the tacky silicone coating composition, wherein the upper surface is less tacky than the lower surface whereby the upper release sheet can be removed from the upper surface more readily than the lower release sheet can be removed from the lower surface. Also provided are methods for making such dressings.

Abstract: A wound dressing material may include a polymeric substrate, a silver salt, and a dyestuff to photostabilize the silver salt. The substrate may include collagen and/or oxidized regenerated cellulose complexed to Ag+, and the dyestuff may, for example, be an aniline or acridine dye. Also disclosed are methods of making such materials, and wound dressings that include such materials.

Abstract: A wound dressing material may include a polymeric substrate, a silver salt, and a dyestuff to photostabilize the silver salt. The substrate may include collagen and/or oxidized regenerated cellulose complexed to Ag+, and the dyestuff may, for example, be an aniline or acridine dye. Also disclosed are methods of making such materials, and wound dressings that include such materials.

Abstract: A silver-containing tissue dressing for providing antimicrobial properties to a wound site is disclosed. In some embodiments, the tissue dressing may include a wound contact layer having a substrate material coated with a tacky hydrophobic silicone material, and silver-containing particles dispersed in the silicone material. The different surfaces of the substrate material may be coated with the silicone material having various amounts of tackiness. The silver material may provide antimicrobial properties when the tissue dressing is placed in contact with the wound site.

Abstract: A wound dressing comprising: a water-absorbent fabric comprising at least about 10 wt. % of hydrogel-forming absorbent fibers based on the dry weight of the fabric; and an adhesion-resistant, water-permeable wound contacting surface textile layer that is substantially continuously bonded to at least one surface of said fabric. The surface textile layer may be formed by surface treatment of the fabric, or by bonding a suitable textile web to the surface of the fabric.

Abstract: A wound dressing comprising: a water-absorbent fabric comprising at least about 10 wt. % of hydrogel-forming absorbent fibers based on the dry weight of the fabric; and an adhesion-resistant, water-permeable wound contacting surface textile layer that is substantially continuously bonded to at least one surface of said fabric. The surface textile layer may be formed by surface treatment of the fabric, or by bonding a suitable textile web to the surface of the fabric.

Abstract: A method of applying a patterned coating of a silicone adhesive to a substrate sheet, comprising the steps of pattern coating a silicone precursor composition onto the substrate, followed by thermally curing the precursor composition coated on the substrate. The precursor composition is a viscous fluid, and the pattern coating is performed by suitably modified block printing, intaglio printing or screen printing methods. Also provided are coated substrates obtainable by the methods of the invention, and wound dressings comprising such coated substrates.

Abstract: A method of applying a patterned coating of a silicone adhesive to a substrate sheet, comprising the steps of pattern coating a silicone precursor composition onto the substrate, followed by thermally curing the precursor composition coated on the substrate. The precursor composition is a viscous fluid, and the pattern coating is performed by suitably modified block printing, intaglio printing or screen printing methods. Also provided are coated substrates obtainable by the methods of the invention, and wound dressings comprising such coated substrates.

Abstract: A wound dressing product comprising: a substrate layer having an upper surface and a lower surface; a tacky silicone coating composition present on said upper surface and on said lower surface; and upper and lower release sheets covering said substrate and said tacky silicone coating composition on said upper and lower surfaces, respectively, and adhered to said surfaces by said tacky silicone coating composition, wherein said upper surface is less tacky than said lower surface whereby said upper release sheet can be removed from said upper surface more readily than said lower release sheet can be removed from said lower surface. Also provided are methods for making such dressings.

Abstract: A wound dressing material comprising a solid bioabsorbable substrate dyed with an antioxidant dyestuff. The substrate may comprise collagen, chitosan or oxidized regenerated cellulose, and the dyestuff may for example be an aniline or acridine dye. The material preferably also comprises a silver salt, whereby the dyestuff stabilizes the silver salt. Also provided are methods of making such materials, and wound dressings comprising such materials.

Abstract: A wound dressing product comprising: a substrate layer having an upper surface and a lower surface; a tacky silicone coating composition present on said upper surface and on said lower surface; and upper and lower release sheets covering said substrate and said tacky silicone coating composition on said upper and lower surfaces, respectively, and adhered to said surfaces by said tacky silicone coating composition, wherein said upper surface is less tacky than said lower surface whereby said upper release sheet can be removed from said upper surface more readily than said lower release sheet can be removed from said lower surface. The same silicone composition is used to form both the upper and the lower surface. Also provided are methods for making such dressings.