Patents by Inventor Deborah Buffington

Deborah Buffington has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230277746
    Abstract: The present invention relates to systems and devices to treat and/or prevent inflammatory conditions within a subject and to related methods. More particularly, the invention relates to systems, devices, and related methods that sequester leukocytes and/or platelets and then inhibit their inflammatory action.
    Type: Application
    Filed: October 3, 2022
    Publication date: September 7, 2023
    Inventors: H. David Humes, Deborah Buffington
  • Publication number: 20200038578
    Abstract: The present invention relates to systems and devices to treat and/or prevent inflammatory conditions within a subject and to related methods. More particularly, the invention relates to systems, devices, and related methods that sequester leukocytes and/or platelets and then inhibit their inflammatory action.
    Type: Application
    Filed: March 20, 2019
    Publication date: February 6, 2020
    Inventors: H. David Humes, Deborah Buffington
  • Publication number: 20170246208
    Abstract: The present invention relates to systems and devices to treat and/or prevent inflammatory conditions within a subject and to related methods. More particularly, the invention relates to systems, devices, and related methods that sequester leukocytes and/or platelets and then inhibit their inflammatory action.
    Type: Application
    Filed: October 14, 2016
    Publication date: August 31, 2017
    Inventors: H. David Humes, Deborah Buffington
  • Patent number: 9498566
    Abstract: The present invention relates to systems and devices to treat and/or prevent inflammatory conditions within a subject and to related methods. More particularly, the invention relates to systems, devices, and related methods that sequester leukocytes and/or platelets and then inhibit their inflammatory action.
    Type: Grant
    Filed: June 25, 2012
    Date of Patent: November 22, 2016
    Assignees: CYTOPHERX, INC., THE REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: H. David Humes, Deborah Buffington
  • Patent number: 9341626
    Abstract: The present invention relates to systems and devices to treat and/or prevent inflammatory conditions within a subject and to related methods. More particularly, the invention relates to systems, devices, and related methods that sequester leukocytes and/or platelets and then inhibit their inflammatory action.
    Type: Grant
    Filed: April 15, 2011
    Date of Patent: May 17, 2016
    Assignees: CYTOPHERX, INC., THE REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: H. David Humes, Deborah Buffington
  • Patent number: 9128093
    Abstract: The present invention relates to systems and devices to treat and/or prevent inflammatory conditions within a subject and to related methods. More particularly, the invention relates to systems, devices, and related methods that sequester leukocytes and/or platelets and then inhibit their inflammatory action.
    Type: Grant
    Filed: June 25, 2012
    Date of Patent: September 8, 2015
    Assignees: THE REGENTS OF THE UNIVERSITY OF MICHIGAN, CYTOPHERX, INC.
    Inventors: H. David Humes, Deborah Buffington
  • Publication number: 20130288370
    Abstract: The present invention relates to a cytopheretic cartridge for use in treating and/or preventing inflammatory conditions within a subject and to related methods. More particularly, the invention relates to a cytopheretic cartridge that includes a housing and, disposed within the housing, a solid support capable of sequestering activated leukocytes and/or platelets.
    Type: Application
    Filed: October 14, 2011
    Publication date: October 31, 2013
    Applicant: CYTOPHERX, INC.
    Inventors: H. David Humes, Deborah Buffington, Christopher J. Pino
  • Patent number: 8430832
    Abstract: The present invention relates to systems and devices to treat and/or prevent inflammatory conditions within a subject and to related methods. More particularly, the invention relates to systems, devices, and related methods that sequester leukocytes and/or platelets and then inhibit their inflammatory action.
    Type: Grant
    Filed: June 30, 2010
    Date of Patent: April 30, 2013
    Assignees: The Regents of the University of Michigan, CytoPherx, Inc.
    Inventors: H. David Humes, Deborah Buffington
  • Patent number: 8425447
    Abstract: The present invention relates to systems and devices to treat and/or prevent inflammatory conditions within a subject and to related methods. More particularly, the invention relates to systems, devices, and related methods that sequester leukocytes and/or platelets and then inhibit their inflammatory action.
    Type: Grant
    Filed: August 23, 2012
    Date of Patent: April 23, 2013
    Assignees: The Regents of the University of Michigan, CytoPherx, Inc.
    Inventors: H. David Humes, Deborah Buffington
  • Patent number: 8425445
    Abstract: The present invention relates to systems and devices to treat and/or prevent inflammatory conditions within a subject and to related methods. More particularly, the invention relates to systems, devices, and related methods that sequester leukocytes and/or platelets and then inhibit their inflammatory action.
    Type: Grant
    Filed: June 30, 2010
    Date of Patent: April 23, 2013
    Assignees: The Regents of the University of Michigan, CytoPherx, Inc.
    Inventors: H. David Humes, Deborah Buffington
  • Patent number: 8425446
    Abstract: The present invention relates to systems and devices to treat and/or prevent inflammatory conditions within a subject and to related methods. More particularly, the invention relates to systems, devices, and related methods that sequester leukocytes and/or platelets and then inhibit their inflammatory action.
    Type: Grant
    Filed: June 30, 2010
    Date of Patent: April 23, 2013
    Assignees: The Regents of the University of Michigan, CytoPherx, Inc.
    Inventors: H. David Humes, Deborah Buffington
  • Patent number: 8409126
    Abstract: The present invention relates to systems and devices to treat and/or prevent inflammatory conditions within a subject and to related methods. More particularly, the invention relates to systems, devices, and related methods that sequester leukocytes and/or platelets and then inhibit their inflammatory action.
    Type: Grant
    Filed: June 30, 2010
    Date of Patent: April 2, 2013
    Assignees: The Regents of the University of Michigan, CytoPherx, Inc.
    Inventors: H. David Humes, Deborah Buffington
  • Publication number: 20120323224
    Abstract: The present invention relates to systems and devices to treat and/or prevent inflammatory conditions within a subject and to related methods. More particularly, the invention relates to systems, devices, and related methods that sequester leukocytes and/or platelets and then inhibit their inflammatory action.
    Type: Application
    Filed: August 23, 2012
    Publication date: December 20, 2012
    Applicants: CYTOPHERX, INC., THE REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: H. David Humes, Deborah Buffington
  • Publication number: 20120322138
    Abstract: The present invention relates to systems and devices to treat and/or prevent inflammatory conditions within a subject and to related methods. More particularly, the invention relates to systems, devices, and related methods that sequester leukocytes and/or platelets and then inhibit their inflammatory action.
    Type: Application
    Filed: August 23, 2012
    Publication date: December 20, 2012
    Applicants: CYTOPHERX, INC., THE REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: H. David Humes, Deborah Buffington
  • Publication number: 20120277720
    Abstract: The present invention relates to systems and devices to treat and/or prevent inflammatory conditions within a subject and to related methods. More particularly, the invention relates to systems, devices, and related methods that sequester leukocytes and/or platelets and then inhibit their inflammatory action.
    Type: Application
    Filed: June 25, 2012
    Publication date: November 1, 2012
    Applicants: CYTOPHERX, INC., THE REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: H. David Humes, Deborah Buffington
  • Publication number: 20120258011
    Abstract: The present invention relates to systems and devices to treat and/or prevent inflammatory conditions within a subject and to related methods. More particularly, the invention relates to systems, devices, and related methods that sequester leukocytes and/or platelets and then inhibit their inflammatory action.
    Type: Application
    Filed: June 25, 2012
    Publication date: October 11, 2012
    Applicants: CYTOPHERX, INC., THE REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: H. David Humes, Deborah Buffington
  • Patent number: 8251941
    Abstract: The present invention relates to systems and devices to treat and/or prevent inflammatory conditions within a subject and to related methods. More particularly, the invention relates to systems, devices, and related methods that sequester leukocytes and/or platelets and then inhibit their inflammatory action.
    Type: Grant
    Filed: August 29, 2008
    Date of Patent: August 28, 2012
    Assignees: The Regents of the University of Michigan, CytoPherx, Inc.
    Inventors: H. David Humes, Deborah Buffington
  • Publication number: 20110196280
    Abstract: The present invention relates to systems and devices to treat and/or prevent inflammatory conditions within a subject and to related methods. More particularly, the invention relates to systems, devices, and related methods that sequester leukocytes and/or platelets and then inhibit their inflammatory action.
    Type: Application
    Filed: April 15, 2011
    Publication date: August 11, 2011
    Applicants: THE REGENTS OF THE UNIVERSITY OF MICHIGAN, INNOVATIVE BIOTHERAPIES, INC.
    Inventors: H. David Humes, Deborah Buffington
  • Publication number: 20110190679
    Abstract: Extracorporeal cell-based therapeutic devices and delivery systems are disclosed which provide a method for therapeutic delivery of biologically active molecules produced by living cells in response to a dynamic physiologic environment. One embodiment includes long hollow fibers in which a layer of cells are grown within the intraluminal volume or within a double hollow-filled chamber. Another embodiment includes a wafer or a series of wafers providing a substrate onto which cells are grown. The wafer(s) are inserted into a device. A device may deliver a pre-selected molecule, for example, a hormone, into a mammal's systemic circulation and/or may deliver a member of different cell products. The device is adapted to secure viable cells which produce and secrete the pre-selected molecule into blood or fluid. The invention also provides a minimally invasive method for percutaneously introducing into a preselected blood vessel or body cavity the device of the invention.
    Type: Application
    Filed: February 15, 2011
    Publication date: August 4, 2011
    Applicant: Innovative BioTherapies, Inc.
    Inventors: H. David Humes, Deborah Buffington, Gretchen Hageman
  • Publication number: 20100266563
    Abstract: The present invention relates to systems and devices to treat and/or prevent inflammatory conditions within a subject and to related methods. More particularly, the invention relates to systems, devices, and related methods that sequester leukocytes and/or platelets and then inhibit their inflammatory action.
    Type: Application
    Filed: June 30, 2010
    Publication date: October 21, 2010
    Applicants: THE REGENTS OF THE UNIVERSITY OF MICHIGAN, INNOVATIVE BIOTHERAPIES, INC.
    Inventors: H. David Humes, Deborah Buffington