Patents by Inventor Deborah C. Mash

Deborah C. Mash has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • L-serine compositions, methods and uses for treating neurodegenerative diseases and disorders
    Patent number: 11974551
    Abstract: L-serine, L-serine precursors, L-serine derivatives and L-serine conjugates for treatment, amelioration and/or prevention of protein aggregation/tangles/plaques and diseases associated with protein aggregation/tangles/plaques. In particular, treatments and uses for L-serine, L-serine precursors, L-serine derivatives and L-serine conjugates include Alzheimer's disease (AD), Parkinson's disease, Amyotrophic Lateral Sclerosis (ALS), and Huntington disease (HD).
    Type: Grant
    Filed: July 12, 2021
    Date of Patent: May 7, 2024
    Assignee: THE INSTITUTE FOR ETHNOMEDICINE
    Inventors: Paul Alan Cox, Sandra Anne Banack, Deborah C. Mash
  • L-serine compositions, methods and uses for treating neurodegenerative diseases and disorders
    Patent number: 11917986
    Abstract: L-serine, L-serine precursors, L-serine derivatives and L-serine conjugates for treatment, amelioration and/or prevention of protein aggregation/tangles/plaques and diseases associated with protein aggregation/tangles/plaques. In particular, treatments and uses for L-serine, L-serine precursors, L-serine derivatives and L-serine conjugates include Alzheimer's disease (AD), Parkinson's disease, Amyotrophic Lateral Sclerosis (ALS), and Huntington disease (HD).
    Type: Grant
    Filed: March 28, 2014
    Date of Patent: March 5, 2024
    Assignee: THE INSTITUTE FOR ETHNOMEDICINE
    Inventors: Paul Alan Cox, Sandra Anne Banack, Deborah C. Mash
  • L-SERINE COMPOSITIONS, METHODS AND USES FOR TREATING NEURODEGENERATIVE DISEASES AND DISORDERS
    Publication number: 20220000082
    Abstract: L-serine, L-serine precursors, L-serine derivatives and L-serine conjugates for treatment, amelioration and/or prevention of protein aggregation/tangles/plaques and diseases associated with protein aggregation/tangles/plaques. In particular, treatments and uses for L-serine, L-serine precursors, L-serine derivatives and L-serine conjugates include Alzheimer's disease (AD), Parkinson's disease, Amyotrophic Lateral Sclerosis (ALS), and Huntington disease (HD).
    Type: Application
    Filed: July 12, 2021
    Publication date: January 6, 2022
    Inventors: Paul Alan COX, Sandra Anne BANACK, Deborah C. MASH
  • NORIBOGAINE COMPOSITIONS
    Publication number: 20210275538
    Abstract: Disclosed are noribogaine compositions comprising a very high level of the 2(R), 4(S), 5(S), 6(S) and 18(R) enantiomer and not more than 0.5 wt % of ibogaine relative to the total amount of noribogaine.
    Type: Application
    Filed: March 16, 2021
    Publication date: September 9, 2021
    Inventors: Robert M. Moriarty, Deborah C. Mash
  • NORIBOGAINE COMPOSITIONS
    Publication number: 20190262351
    Abstract: Disclosed are noribogaine compositions comprising a very high level of the 2(R), 4(S), 5(S), 6(S) and 18(R) enantiomer and not more than 0.5 wt % of ibogaine relative to the total amount of noribogaine.
    Type: Application
    Filed: June 3, 2016
    Publication date: August 29, 2019
    Applicant: DemeRx, Inc.
    Inventors: Robert M. Moriarty, Deborah C. Mash
  • Substituted noribogaine
    Patent number: 9783535
    Abstract: This invention relates noribogaine derivatives, compositions and methods of use thereof.
    Type: Grant
    Filed: December 20, 2012
    Date of Patent: October 10, 2017
    Inventors: Deborah C. Mash, Richard D. Gless, Robert M. Moriarty
  • N-substituted noribogaine prodrugs
    Patent number: 9586954
    Abstract: This invention relates generally to prodrugs of noribogaine. This invention also relates to pharmaceutical compositions comprising the prodrugs of noribogaine as well as method of treating pain, addiction and/or stress using such compounds and/or pharmaceutical compositions.
    Type: Grant
    Filed: April 21, 2014
    Date of Patent: March 7, 2017
    Assignee: DEMERX, INC.
    Inventor: Deborah C. Mash
  • Stereoselective total synthesis of noribogaine
    Patent number: 9403837
    Abstract: This invention relates generally to methods for synthesizing the non-addictive alkaloid noribogaine.
    Type: Grant
    Filed: September 15, 2014
    Date of Patent: August 2, 2016
    Assignee: DEMERX, INC.
    Inventors: Robert M. Moriarty, Deborah C. Mash
  • Methods and compositions for preparing noribogaine from voacangine
    Patent number: 9403817
    Abstract: Disclosed are methods and compositions for preparing and purifying the non-addictive alkaloid noribogaine.
    Type: Grant
    Filed: October 14, 2014
    Date of Patent: August 2, 2016
    Assignee: DEMERX, INC.
    Inventors: Deborah C. Mash, Robert M. Moriarty, Richard D. Gless, Jr.
  • Methods and compositions for preparing and purifying noribogaine
    Patent number: 9394294
    Abstract: Disclosed are methods and compositions for purifying the non-addictive alkaloid noribogaine.
    Type: Grant
    Filed: June 6, 2014
    Date of Patent: July 19, 2016
    Assignee: DEMERX, INC.
    Inventors: Deborah C. Mash, Richard D. Gless, Jr.
  • Noribogaine compositions
    Patent number: 9358237
    Abstract: Disclosed are noribogaine compositions comprising a very high level of the 2(R), 4(S), 5(S), 6(S) and 18(R) enantiomer and not more than 0.5 wt % of ibogaine relative to the total amount of noribogaine.
    Type: Grant
    Filed: July 22, 2011
    Date of Patent: June 7, 2016
    Assignee: DEMERX, INC.
    Inventors: Robert M. Moriarty, Deborah C. Mash
  • Compositions comprising noribogaine and an excipient to facilitate transport across the blood brain barrier
    Patent number: 9308272
    Abstract: This invention relates generally to compositions comprising noribogaine and an excipient to facilitate transport across the blood brain barrier.
    Type: Grant
    Filed: July 3, 2014
    Date of Patent: April 12, 2016
    Assignee: DEMERX, INC.
    Inventors: Deborah C. Mash, Richard D. Gless
  • SUBSTITUTED NORIBOGAINE
    Publication number: 20150361080
    Abstract: This invention relates noribogaine derivatives, compositions and methods of use thereof.
    Type: Application
    Filed: May 21, 2015
    Publication date: December 17, 2015
    Applicant: DemeRx, Inc.
    Inventors: Deborah C. Mash, Richard D. Gless, JR., Robert M. Moriarty
  • SUBSTITUTED NORIBOGAINE
    Publication number: 20150329536
    Abstract: This invention relates noribogaine derivatives, compositions and methods of use thereof.
    Type: Application
    Filed: December 20, 2012
    Publication date: November 19, 2015
    Inventors: Deborah C. Mash, Richard D. Gless, Robert M. Moriarty
  • Substituted noribogaine
    Patent number: 9045481
    Abstract: This invention relates noribogaine derivatives, compositions and methods of use thereof.
    Type: Grant
    Filed: January 29, 2013
    Date of Patent: June 2, 2015
    Assignee: DEMERX, INC.
    Inventors: Deborah C. Mash, Richard D. Gless, Jr., Robert M. Moriarty
  • METHODS AND COMPOSITIONS FOR PREPARING NORIBOGAINE FROM VOACANGINE
    Publication number: 20150133655
    Abstract: Disclosed are methods and compositions for preparing and purifying the non-addictive alkaloid noribogaine.
    Type: Application
    Filed: October 14, 2014
    Publication date: May 14, 2015
    Applicant: DEMERX, INC.
    Inventors: Deborah C. Mash, Robert M. Moriarty, Richard D. Gless, JR.
  • Substituted noribogaine
    Patent number: 8940728
    Abstract: This invention relates noribogaine derivatives, compositions and methods of use thereof.
    Type: Grant
    Filed: January 2, 2013
    Date of Patent: January 27, 2015
    Assignee: DemeRx, Inc.
    Inventors: Deborah C. Mash, Richard D. Gless, Jr., Robert M. Moriarty
  • Stereoselective total synthesis of noribogaine
    Patent number: 8937061
    Abstract: This invention relates generally to methods for synthesizing the non-addictive alkaloid noribogaine.
    Type: Grant
    Filed: December 7, 2012
    Date of Patent: January 20, 2015
    Assignee: DemeRx, Inc.
    Inventors: Robert M. Moriarty, Deborah C. Mash
  • STEREOSELECTIVE TOTAL SYNTHESIS OF NORIBOGAINE
    Publication number: 20150005492
    Abstract: This invention relates generally to methods for synthesizing the non-addictive alkaloid noribogaine.
    Type: Application
    Filed: September 15, 2014
    Publication date: January 1, 2015
    Applicant: DEMERX, INC.
    Inventors: Robert M. Moriarty, Deborah C. Mash
  • METHODS AND COMPOSITIONS FOR PREPARING AND PURIFYING NORIBOGAINE
    Publication number: 20140357741
    Abstract: Disclosed are methods and compositions for purifying the non-addictive alkaloid noribogaine.
    Type: Application
    Filed: June 6, 2014
    Publication date: December 4, 2014
    Inventors: Deborah C. Mash, Richard D. Gless, JR.