Patents by Inventor Deborah Clark

Deborah Clark has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230053634
    Abstract: Compositions including a CD180 binding ligand and a linked Hepatitis B antigen and their use are disclosed. The Hepatitis B antigen includes Hepatitis B virus pre-S1 and/or pre-S2 region of the HBV envelope protein (HBVpre S1/S2Ag), L-HBsAg, MHBsAg, S-HBsAg, or antigenic fragments or mutants thereof.
    Type: Application
    Filed: July 1, 2022
    Publication date: February 23, 2023
    Inventors: Edward A. CLARK, Che-Leung LAW, Deborah FULLER, Michael GALE
  • Publication number: 20230056043
    Abstract: Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest including plants, as probes for the isolation of other homologous (or partially homologous) genes. The pesticidal proteins find use in controlling, inhibiting growth or killing Lepidopteran, Coleopteran, Dipteran, fungal, Hemipteran and nematode pest populations and for producing compositions with insecticidal activity.
    Type: Application
    Filed: September 23, 2022
    Publication date: February 23, 2023
    Applicants: PIONEER HI-BRED INTERNATIONAL, INC., E. I. DU PONT DE NEMOURS AND COMPANY
    Inventors: JENNIFER KARA BARRY, DEBORAH CLARK, JAMES J ENGLISH, AZALEA S ONG, ERIC SCHEPERS, JULIE QI, JANET RICE
  • Publication number: 20230018537
    Abstract: The present disclosure describes methods and systems for predicting severe disease in an individual with sepsis or at risk of developing sepsis, in order to prevent severe disease in an individual with sepsis. The present disclosure also describes methods of using topological data analysis and/or clustering to stratify sepsis based on biomolecular signatures and identify distinct phenotypes in sepsis patients.
    Type: Application
    Filed: December 24, 2020
    Publication date: January 19, 2023
    Applicant: The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc.
    Inventors: Joost Brandsma, Danielle Clark, Rittal Mehta, Deborah Striegel
  • Patent number: 11492641
    Abstract: Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest including plants, as probes for the isolation of other homologous (or partially homologous) genes. The pesticidal proteins find use in controlling, inhibiting growth or killing Lepidopteran, Coleopteran, Dipteran, fungal, Hemipteran and nematode pest populations and for producing compositions with insecticidal activity.
    Type: Grant
    Filed: July 1, 2020
    Date of Patent: November 8, 2022
    Inventors: Jennifer Kara Barry, Deborah Clark, James J English, Azalea S Ong, Eric Schepers, Julie Qi, Janet Rice
  • Publication number: 20220241403
    Abstract: Provided herein are compositions of CD1280 binding proteins and a Hepatitis B virus core antigen (HBcAg) and/or a Hepatitis B virus E antigen (HBeAg), or antigenic fragments or mutants thereof, attached to the CD180 binding protein, and methods for using the compositions to treat or limit the development of hepatitis-B virus (HBV)-related disorders.
    Type: Application
    Filed: April 15, 2022
    Publication date: August 4, 2022
    Inventors: Edward A. CLARK, Deborah L. FULLER, Che-Leung LAW, Amanda MAK
  • Patent number: 11389532
    Abstract: Compositions including a CD180 binding ligand and a linked Hepatitis B antigen and their use are disclosed. The Hepatitis B antigen includes Hepatitis B virus pre-S1 and/or pre-S2 region of the HBV envelope protein (HBVpreS1/S2Ag), L-HBsAg, MHBsAg, S-HBsAg, or antigenic fragments or mutants thereof.
    Type: Grant
    Filed: November 15, 2018
    Date of Patent: July 19, 2022
    Assignees: University of Washington, Abacus Bioscience, Inc.
    Inventors: Edward A. Clark, Che-Leung Law, Deborah Fuller, Michael Gale
  • Publication number: 20200399653
    Abstract: Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest including plants, as probes for the isolation of other homologous (or partially homologous) genes. The pesticidal proteins find use in controlling, inhibiting growth or killing Lepidopteran, Coleopteran, Dipteran, fungal, Hemipteran and nematode pest populations and for producing compositions with insecticidal activity.
    Type: Application
    Filed: July 1, 2020
    Publication date: December 24, 2020
    Applicants: PIONEER HI-BRED INTERNATIONAL, INC., E. I. DU PONT DE NEMOURS AND COMPANY
    Inventors: JENNIFER KARA BARRY, DEBORAH CLARK, JAMES J ENGLISH, AZALEA S ONG, ERIC SCHEPERS, JULIE QI, JANET RICE
  • Patent number: 10781458
    Abstract: Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest including plants, as probes for the isolation of other homologous (or partially homologous) genes. The pesticidal proteins find use in controlling, inhibiting growth or killing Lepidopteran, Coleopteran, Dipteran, fungal, Hemipteran and nematode pest populations and for producing compositions with insecticidal activity.
    Type: Grant
    Filed: August 19, 2019
    Date of Patent: September 22, 2020
    Assignees: PIONEER HI-BRED INTERNATIONAL, INC., E. I. DU PONT DE NEMOURS AND COMPANY
    Inventors: Jennifer Kara Barry, Deborah Clark, James J English, Azalea S Ong, Eric Schepers, Julie Qi, Janet Rice
  • Publication number: 20200010514
    Abstract: Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest including plants, as probes for the isolation of other homologous (or partially homologous) genes. The pesticidal proteins find use in controlling, inhibiting growth or killing Lepidopteran, Coleopteran, Dipteran, fungal, Hemipteran and nematode pest populations and for producing compositions with insecticidal activity.
    Type: Application
    Filed: August 19, 2019
    Publication date: January 9, 2020
    Applicants: PIONEER HI-BRED INTERNATIONAL, INC., E. I. DU PONT DE NEMOURS AND COMPANY
    Inventors: JENNIFER KARA BARRY, DEBORAH CLARK, JAMES J ENGLISH, AZALEA S ONG, ERIC SCHEPERS, JULIE QI, JANET RICE
  • Patent number: 5859404
    Abstract: A plasma heating apparatus for heating a workpiece includes a chamber of sufficient size to receive a workpiece therein and a source of a reduced gas pressure within the chamber of from about 0.01 to about 100 millitorr. The plasma heating apparatus further includes a plasma source of an enveloping plasma. Optionally, a workpiece voltage may be applied between the workpiece and the wall of the chamber, and a source of a reactive gas can be provided to backfill the chamber, and radiant heaters can be provided to independently heat portions of the workpiece. In operation, the plasma source produces a plasma that surrounds and heats the workpiece. The plasma and the heating of the workpiece are tailored to achieve controllably uniform or nonuniform heat treatment and/or surface treatment of the workpiece.
    Type: Grant
    Filed: October 12, 1995
    Date of Patent: January 12, 1999
    Assignees: Hughes Electronics Corporation, General Motors Corporation
    Inventors: Ronghua R. Wei, Jesse N. Matossian, Peter Mikula, Deborah Clark
  • Patent number: 5383112
    Abstract: A method of managing information used and generated in the scheduling and exhibition of performances is disclosed. A video network includes a video server that operates several video recorders to simultaneously exhibit video performances or programs on a plurality of channels. The video server is controlled in real time in accordance with data presented to it in an exhibition plan. The exhibition plan is generated through the performance of an exhibition manager process which operates on a computer. The exhibition manager manages information related to the performances to be exhibited, schedules the performances in accordance with user-supplied timing data, prints reports, and maintains a personal information manager having a database describing studios, contacts, and other information related to licensing the performances for exhibition on the network. The information related to performances includes repeat factors and short titles which the exhibition manager calculates.
    Type: Grant
    Filed: January 7, 1991
    Date of Patent: January 17, 1995
    Assignee: GTE Service Corporation
    Inventor: P. Deborah Clark