Patents by Inventor Deborah J. Boles

Deborah J. Boles has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method and apparatus for generating thermal melting curves in a microfluidic device
    Patent number: 11162910
    Abstract: The present invention provides novel methods and devices that employ microfluidic technology to generate molecular melt curves. In particular, the devices and methods in accordance with the invention are useful in providing for the analysis of PCR amplification products.
    Type: Grant
    Filed: June 27, 2016
    Date of Patent: November 2, 2021
    Assignees: CALIPER LIFE SCIENCES, INC., Canon U.S.A., Inc.
    Inventors: Steven A. Sundberg, Michael R. Knapp, Ivor T. Knight, Deborah J. Boles, Aaron Rulison, Wesley B. Dong, Andrew Fabans, Edward Donlon, Robert Moti, Michael Slater
  • Method and apparatus for applying continuous flow and uniform temperature to generate thermal melting curves in a microfluidic device
    Patent number: 9580744
    Abstract: The present invention provides a method for performing thermal melt analysis using a microfluidic device, the method comprising providing a microfluidic device having at least one microfluidic channel, introducing fluid comprising into the at least one microfluidic channel, continuously flowing the fluid through the at least one microfluidic channel while varying the temperature of the entire fluid stream as it moves through the at least one microfluidic channel by uniformly heating the entire fluid stream, and measuring, while continuously flowing the fluid through the at least one microfluidic channel, a detectable property emanating from the fluid.
    Type: Grant
    Filed: July 15, 2014
    Date of Patent: February 28, 2017
    Assignee: Canon U.S. Life Sciences, Inc.
    Inventors: Ivor T. Knight, Deborah J. Boles
  • METHOD AND APPARATUS FOR GENERATING THERMAL MELTING CURVES IN A MICROFLUIDIC DEVICE
    Publication number: 20160377562
    Abstract: The present invention provides novel methods and devices that employ microfluidic technology to generate molecular melt curves. In particular, the devices and methods in accordance with the invention are useful in providing for the analysis of PCR amplification products.
    Type: Application
    Filed: June 27, 2016
    Publication date: December 29, 2016
    Applicants: CALIPER LIFE SCIENCES, INC., CANON U.S. LIFE SCIENCES, INC.
    Inventors: Steven A. Sundberg, Michael R. Knapp, Ivor T. Knight, Deborah J. Boles, Aaron Rulison, Wesley B. Dong, Andrew Fabans, Allen Boronkay, Edwawrd Donlon, Robert Moti, Michael Slater
  • Method and apparatus for generating thermal melting curves in a microfluidic device
    Patent number: 9376718
    Abstract: The present invention provides novel methods and devices that employ microfluidic technology to generate molecular melt curves. In particular, the devices and methods in accordance with the invention are useful in providing for the analysis of PCR amplification products.
    Type: Grant
    Filed: April 11, 2012
    Date of Patent: June 28, 2016
    Assignees: Caliper Life Sciences, Inc., Canon U.S. Life Sciences, Inc.
    Inventors: Steven A. Sundberg, Michael R. Knapp, Ivor T. Knight, Deborah J. Boles, Aaron J. Rulison, Wesley B. Dong, Edward P. Donlon, Robert J. Moti, Andrew G. Fabans, Allen R. Boronkay, Michael Slater
  • Method and apparatus for generating thermal melting curves in a microfluidic device
    Patent number: 8900811
    Abstract: The present invention provides novel methods and devices that employ microfluidic technology to generate molecular melt curves. In particular, the devices and methods in accordance with the invention are useful in providing for the analysis of PCR amplification products.
    Type: Grant
    Filed: February 9, 2006
    Date of Patent: December 2, 2014
    Assignees: Caliper Life Sciences, Inc., Canon U.S. Life Sciences, Inc.
    Inventors: Steven A. Sundberg, Michael R. Knapp, Ivor T. Knight, Deborah J. Boles, Aaron J. Rulison, Wesley B. Dong, Andrew G. Fabans, Allen R. Boronkay, Edward P. Donlon, Robert J. Moti, Michael Slater
  • METHOD AND APPARATUS FOR GENERATING THERMAL MELTING CURVES IN A MICROFLUIDIC DEVICE
    Publication number: 20120288865
    Abstract: The present invention provides novel methods and devices that employ microfluidic technology to generate molecular melt curves. In particular, the devices and methods in accordance with the invention are useful in providing for the analysis of PCR amplification products.
    Type: Application
    Filed: April 11, 2012
    Publication date: November 15, 2012
    Applicants: Canon U.S. Life Sciences, Inc., Caliper Life Sciences, Inc.
    Inventors: Steven A. Sundberg, Michael R. Knapp, Ivor T. Knight, Deborah J. Boles, Aaron J. Rulison, Wesley B. Dong, Edward P. Donlon, Robert J. Moti, Andrew G. Fabans, Allen R. Boronkay, Michael Slater