Patents by Inventor Deborah J. Brame

Deborah J. Brame has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5861110
    Abstract: A method for production of high specific surface area silica gel by hydrolysis of silicon tetrahalide, wherein a solution of silicon tetrahalide in a non-reactive solvent such as alcohol is mixed with water to produce silica gel having a high surface area and narrow pore diameter distribution especially suited for use as normal phase packing material in high performance chromatography columns. The water contains fluoride ions if the halide is chloride. Reverse phase packing material can be prepared by reacting the normal phase silica gel with organochlorosilanes to prepare bonded reverse phase material for use in high performance liquid chromotagraphy systems.
    Type: Grant
    Filed: July 10, 1992
    Date of Patent: January 19, 1999
    Inventors: Paul C. Chieng, Deborah J. Brame, Alexander H. T. Chu
  • Patent number: 5158758
    Abstract: A method for production of high specific surface area silica gel by hydrolysis of silicon tetrahalide, wherein a solution of silicon tetrahalide in a non-reactive solvent such as alcohol is mixed with water to produce silica gel having a high surface area and narrow pore diameter distribution especially suited for use as normal phase packing material in high performance chromatography columns. The water contains fluoride ions if the halide is chloride. Reverse phase packing material can be prepared by reacting the normal phase silica gel with organochlorosilanes to prepare bonded reverse phase material for use in high performance liquid chromotagraphy systems.
    Type: Grant
    Filed: April 24, 1989
    Date of Patent: October 27, 1992
    Assignee: International Minerals & Chemical Corp.
    Inventors: Paul C. Chieng, Deborah J. Brame, Alexander H. T. Chu