Patents by Inventor Deborah Lewinsohn

Deborah Lewinsohn has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20120014881
    Abstract: Methods for detecting an infection with Mycobacterium tuberculosis (Mtb) in a subject are disclosed. The methods include detecting the presence of CD8+ T cells that specifically recognize an Mtb polypeptide. The methods include in vitro assays for detecting the presence of CD8+ T cells in a biological sample, and in vivo assays that detect a delayed type hypersensitivity reaction. The methods can also include detecting Mtb polypeptides and polynucleotides. Reagents for the detection of an Mtb infection are also disclosed.
    Type: Application
    Filed: September 23, 2011
    Publication date: January 19, 2012
    Inventors: David M. Lewinsohn, Deborah A. Lewinsohn
  • Patent number: 8053181
    Abstract: Methods for detecting an infection with Mycobacterium tuberculosis (Mtb) in a subject are disclosed. The methods include detecting the presence of CD8+T cells that specifically recognize an Mtb polypeptide. The methods include in vitro assays for detecting the presence of CD8+T cells in a biological sample, and in vivo assays that detect a delayed type hypersensitivity reaction. The methods can also include detecting Mtb polypeptides and polynucleotides. Reagents for the detection of an Mtb infection are also disclosed.
    Type: Grant
    Filed: March 14, 2007
    Date of Patent: November 8, 2011
    Assignees: Oregon Health & Science University, The United States of America as represented by the Department of Veterans Affairs
    Inventors: David M. Lewinsohn, Deborah A. Lewinsohn
  • Publication number: 20110183342
    Abstract: Methods for detecting an infection with Mycobacterium tuberculosis (Mtb) in a subject are disclosed, wherein the subject is a child, a subject with a latent Mycobacterium tuberculosis infection. Method are also disclose for detecting an extra-pulmonary Mycobacterium tuberculosis infection in a subject. The methods include detecting the presence of CD8+ T cells that specifically recognize an Mtb polypeptide. The methods include in vitro assays for detecting the presence of CD8+ T cells in a biological sample.
    Type: Application
    Filed: September 22, 2009
    Publication date: July 28, 2011
    Inventors: Deborah A. Lewinsohn, David M. Lewinsohn
  • Publication number: 20110014224
    Abstract: Methods for producing an immune response to Mycobacterium tuberculosis (Mtb) are disclosed herein. In several examples, the immune response is a protective immune response. In additional embodiments, methods are disclosed for preventing an infection with Mtb, or treating an infection with Mtb. Pharmaceutical compositions for the prevention and/or treatment of tuberculosis are also disclosed.
    Type: Application
    Filed: September 29, 2010
    Publication date: January 20, 2011
    Inventors: David Lewinsohn, Deborah Lewinsohn
  • Patent number: 7842299
    Abstract: Methods for producing an immune response to Mycobacterium tuberculosis (Mtb) are disclosed herein. In several examples, the immune response is a protective immune response. In additional embodiments, methods are disclosed for preventing an infection with Mtb, or treating an infection with Mtb. Pharmaceutical compositions for the prevention and/or treatment of tuberculosis are also disclosed.
    Type: Grant
    Filed: March 14, 2007
    Date of Patent: November 30, 2010
    Assignees: Oregon Health & Science University, The United States of America as represented by the Department of Veterans Affairs
    Inventors: David Lewinsohn, Deborah Lewinsohn
  • Publication number: 20090324503
    Abstract: Methods for detecting an infection with Mycobacterium tuberculosis (Mtb) in a subject are disclosed. The methods include detecting the presence of CD8+ T cells that specifically recognize an Mtb polypeptide. The methods include in vitro assays for detecting the presence of CD8+ T cells in a biological sample, and in vivo assays that detect a delayed type hypersensitivity reaction. The methods can also include detecting Mtb polypeptides and polynucleotides. Reagents for the detection of an Mtb infection are also disclosed.
    Type: Application
    Filed: March 14, 2007
    Publication date: December 31, 2009
    Inventors: David M. Lewinsohn, Deborah A. Lewinsohn
  • Publication number: 20090124549
    Abstract: Methods for producing an immune response to Mycobacterium tuberculosis (Mtb) are disclosed herein. In several examples, the immune response is a protective immune response. In additional embodiments, methods are disclosed for preventing an infection with Mtb, or treating an infection with Mtb. Pharmaceutical compositions for the prevention and/or treatment of tuberculosis are also disclosed.
    Type: Application
    Filed: March 14, 2007
    Publication date: May 14, 2009
    Inventors: David Lewinsohn, Deborah Lewinsohn