Patents by Inventor Deborah Lynne Bryan

Deborah Lynne Bryan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 4-AMINO-2,3-DISUBSTITUTED THIENO [2,3,D]PYRIMIDINES AND PHARMACEUTICAL COMPOSITIONS THEREOF
    Publication number: 20080287466
    Abstract: Furo- and thienopyrimidine derivatives, which are useful as TIE-2 and/or VEGFR-2 inhibitors are described herein. The described invention also includes methods of making such furo- and thienopyrimidine derivatives as well as methods of using the same in the treatment of hyperproliferative diseases.
    Type: Application
    Filed: July 9, 2008
    Publication date: November 20, 2008
    Inventors: Jerry Leroy Adams, Deborah Lynne Bryan, Yanhong Feng, Shinichiro Matsunaga, Yutaka Maeda, Yasushi Miyazaki, Masato Nakano, Jean-Philippe Rocher, Hideyuki Sato, Marcus Semones, Domingos J. Silva, Jun Tang
  • 4-Amino-2,3-disubstituted thieno[2,3-d]pyrimidines and pharmacetical compositions thereof
    Patent number: 7427623
    Abstract: Furo- and thienopyrimidine derivatives, which are useful as TIE-2 and/or VEGFR-2 inhibitors are described herein. The described invention also includes methods of making such furo- and thienopyrimidine derivatives as well as methods of using the same in the treatment of hyperproliferative diseases.
    Type: Grant
    Filed: September 10, 2002
    Date of Patent: September 23, 2008
    Assignee: SmithKline Beecham Corporation
    Inventors: Jerry Leroy Adams, Deborah Lynne Bryan, Yanhong Feng, Shinichiro Matsunaga, Yutaka Maeda, Yasushi Miyazaki, Masato Nakano, Jean-Philippe Rocher, Hideyuki Sato, Marcus Semones, Domingos J. Silva, Jun Tang
  • Endothelin receptor antagonists
    Patent number: 6127371
    Abstract: Novel indane and indene derivatives are described which are endothelin receptor antagonists.
    Type: Grant
    Filed: October 1, 1999
    Date of Patent: October 3, 2000
    Assignee: SmithKline Beecham Corporation
    Inventors: John Duncan Elliott, Deborah Lynne Bryan
  • Endothelin receptor antagonists
    Patent number: 5985886
    Abstract: Novel indane and indene derivatives are described which are endothelin receptor antagonists.
    Type: Grant
    Filed: June 16, 1998
    Date of Patent: November 16, 1999
    Assignee: SmithKline Beecham Corporation
    Inventors: John Duncan Elliott, Deborah Lynne Bryan
  • Endothelin receptor antagonists
    Patent number: 5942516
    Abstract: Novel pyridines, pyrimidines, pyrazines, pyridazines and triazines, pharmaceutical compositions containing these compounds and their use as endothelin receptor antagonists are described.
    Type: Grant
    Filed: September 27, 1996
    Date of Patent: August 24, 1999
    Inventors: John Duncan Elliott, Deborah Lynne Bryan
  • Cyclopentene derivatives as endothelin receptor antagonists
    Patent number: 5929116
    Abstract: Novel cyclopentane derivatives are described which are endothelin receptor antagonists.
    Type: Grant
    Filed: October 13, 1995
    Date of Patent: July 27, 1999
    Assignee: SmithKline Beecham Corporation
    Inventors: John Duncan Elliott, Deborah Lynne Bryan