Patents by Inventor Deborah M. Slipetz

Deborah M. Slipetz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for treating ocular hypertension
    Publication number: 20040254230
    Abstract: This invention relates to potent selective agonists of the EP4 subtype of prostaglandin E2 receptors, their use or a formulation thereof in the treatment of glaucoma and other conditions that are related to elevated intraocular pressure in the eye of a patient. This invention also relates to the use of such compounds to provide a neuroprotective effect to the eye of mammalian species, particularly humans.
    Type: Application
    Filed: May 4, 2004
    Publication date: December 16, 2004
    Inventors: Miller J. Ogidigben, Robert N. Young, Kathleen M. Metters, Deborah M. Slipetz
  • Ep4 receptor agonist, compositions and methods thereof
    Publication number: 20040204590
    Abstract: This invention relates to potent selective agonists of the EP4 subtype of prostaglandin E2 receptors, their use or a formulation thereof in the treatment of glaucoma and other conditions which are related to elevated intraocular pressure in the eye of a patient. This invention further relates to the use of the compounds of this invention for mediating the bone modeling and remodeling processes of the osteoblasts and osteoclasts.
    Type: Application
    Filed: April 22, 2004
    Publication date: October 14, 2004
    Inventors: Miller J. Ogidigben, Robert N Young, Kathleen M Metters, Deborah M Slipetz
  • Methods of identifying modulators of a DP prostaglandin receptor
    Patent number: 6395499
    Abstract: A human prostaglandin receptor has been identified and DNA encoding the receptor has been isolated, purified, sequenced and expressed in host cells. This DNA encoding the human prostaglandin receptor and host cells expressing the receptor are used to identify modulators of the prostaglandin receptor.
    Type: Grant
    Filed: June 20, 2000
    Date of Patent: May 28, 2002
    Assignee: Merck Frosst Canada & Co.
    Inventors: Mark Abramovitz, Kathleen Metters, Yves Boie, Nicole Sawyer, Deborah M. Slipetz
  • Methods of identifying modulators of human IP prostaglandin receptor
    Patent number: 6365360
    Abstract: A novel prostaglandin receptor has been identified and DNA encoding the receptor has been isolated, purified, sequenced and expressed in host cells. This DNA encoding the novel prostaglandin receptor and host cells expressing the receptor are used to identify modulators of the prostaglandin receptor.
    Type: Grant
    Filed: March 16, 1998
    Date of Patent: April 2, 2002
    Assignee: Merck Frosst Canada & Co.
    Inventors: Mark Abramovitz, Yves Boie, Richard Grygorczyk, Kathleen Metters, Thomas H. Rushmore, Deborah M. Slipetz
  • DNA encoding prostaglandin receptor DP
    Patent number: 6214972
    Abstract: A novel human DP prostaglandin receptor has been identified and DNA encoding the receptor has been isolated, purified, sequenced and expressed in host cells. This DNA encoding the novel prostaglandin receptor and host cells expressing the receptor are used to identify modulators of the prostaglandin receptor.
    Type: Grant
    Filed: April 28, 1999
    Date of Patent: April 10, 2001
    Assignee: Merck Frosst Canada & Co.
    Inventors: Mark Abramovitz, Yves Boie, Kathleen Metters, Nicole Sawyer, Deborah M. Slipetz
  • DNA encoding prostaglandin receptor DP
    Patent number: 5958723
    Abstract: A novel human DP prostaglandin receptor has been identified and DNA encoding the receptor has been isolated, purified, sequenced and expressed in host cells. This DNA encoding the novel prostaglandin receptor and host cells expressing the receptor are used to identify modulators of the prostaglandin receptor.
    Type: Grant
    Filed: March 6, 1997
    Date of Patent: September 28, 1999
    Assignee: Merck Frosst Canada & Co.
    Inventors: Mark Abramovitz, Yves Boie, Kathleen Metters, Nicole Sawyer, Deborah M. Slipetz
  • Human Prostaglandin receptor IP
    Patent number: 5728808
    Abstract: A novel prostaglandin receptor has been identified and DNA encoding the receptor has been isolated, purified, sequenced and expressed in host cells. This DNA encoding the novel prostaglandin receptor and host cells expressing the receptor are used to identify modulators of the prostaglandin receptor.
    Type: Grant
    Filed: August 29, 1995
    Date of Patent: March 17, 1998
    Assignee: Merck Frosst Canada, Inc.
    Inventors: Mark Abramovitz, Yves Bole, Richard Grygorczyk, Kathleen Metters, Thomas H. Rushmore, Deborah M. Slipetz
  • DNA encoding prostaglandin receptor IP
    Patent number: 5516652
    Abstract: A novel prostaglandin receptor has been identified and DNA encoding the receptor has been isolated, purified, sequenced and expressed in host cells. This DNA encoding the novel prostaglandin receptor and host cells expressing the receptor are used to identify modulators of the prostaglandin receptor.
    Type: Grant
    Filed: October 6, 1993
    Date of Patent: May 14, 1996
    Assignee: Merck Frosst Canada Inc.
    Inventors: Mark Abramovitz, Yves Boie, Richard Grygorczyk, Kathleen Metters, Thomas H. Rushmore, Deborah M. Slipetz