Abstract: This invention relates to compounds useful as lysyl oxidase (LOX) and lysyl oxidase-like (LOXL) family member (LOXL1, LOXL2, LOXL3, LOXL4) inhibitors. In addition there are contemplated pharmaceutical compositions comprising the compounds and the use of the compounds in the treatment of conditions mediated by LOX and LOXL, for example cancer. In particular a LOX inhibitor such as the present compounds may be for use in the treatment of a cancer associated with EGFR. The present invention also contemplates the identification of biomarkers that predict responsiveness to a LOX inhibitor.

Abstract: Asynchronous fallback save operations herein (also referred to herein as a background save) provide a means for saving very large transactions from a client device within a stateless architecture. When dealing with large transactions, it may take a long time to process records—so long that the connection between the server and the client may time out, causing the user to lose all work or progress that was being saved. Thus, the present technology serves to prevent this “time out” problem while simultaneously allowing users to continue working on something else while a save is still completing. In some implementations, once a user has submitted a save request, the save operation may be carried out in a background thread pool, allowing the user to continue move on to a new task.

Abstract: This disclosure relates to a system and method to implement a performance test to help evaluate a patient's neurological and cognitive function. The performance test can be executed by the patient autonomously using a portable computing device, such as a tablet computer or smart phone. The portable computing device can be programmed to execute a set of modules configured to assess motor and cognitive performance, such as a manual function test module, a cognitive processing speed test module, and a movement assessment test module. The set of modules can also include a collection module to aggregate test data from the manual function test module, the cognitive processing speed test module, and the movement assessment test module.

Abstract: This disclosure relates to a system and method to implement a performance test to help evaluate a patient's neurological and cognitive function. The performance test can be executed by the patient autonomously using a portable computing device, such as a tablet computer or smart phone. The portable computing device can be programmed to execute a set of modules configured to assess motor and cognitive performance, such as a manual function test module, a cognitive processing speed test module, and a movement assessment test module. The set of modules can also include a collection module to aggregate test data from the manual function test module, the cognitive processing speed test module, and the movement assessment test module.

Abstract: This disclosure relates to a system and method to implement a performance test to help evaluate a patient's neurological and cognitive function. The performance test can be executed by the patient autonomously using a portable computing device, such as a tablet computer or smart phone. The portable computing device can be programmed to execute a set of modules configured to assess motor and cognitive performance, such as a manual function test module, a cognitive processing speed test module, and a movement assessment test module. The set of modules can also include a collection module to aggregate test data from the manual function test module, the cognitive processing speed test module, and the movement assessment test module.

Abstract: Real-time customer feedback of call information is determined by a carrier network. Databases are used to map individual phone numbers to the carrier currently servicing that number and to lookup the carrier information for the other party during each call. This information may be displayed on the customer's handset device. Furthermore, this called party network carrier information could be used in conjunction with information about the calling party's rate plan to display the actual cost status of the call on the customer's handset.

Abstract: This disclosure relates to a system and method to implement a performance test to help evaluate a patient's neurological and cognitive function. The performance test can be executed by the patient autonomously using a portable computing device, such as a tablet computer or smart phone. The portable computing device can be programmed to execute a set of modules configured to assess motor and cognitive performance, such as a manual function test module, a cognitive processing speed test module, and a movement assessment test module. The set of modules can also include a collection module to aggregate test data from the manual function test module, the cognitive processing speed test module, and the movement assessment test module.

Abstract: Real-time customer feedback of call information is determined by a carrier network. Databases are used to map individual phone numbers to the carrier currently servicing that number and to lookup the carrier information for the other party during each call. This information may be displayed on the customer's handset device. Furthermore, this called party network carrier information could be used in conjunction with information about the calling party's rate plan to display the actual cost status of the call on the customer's handset.

Abstract: A method and computer-readable medium for managing order entry by a user via remote connection to an account database system of a service provider are provided. According to the method, order information is received from the user via the remote connection for an account of the user. Payment information is outputted to an external payment service for authorization of payment, and, if the authorization is successful, order information is received and written to a custom database of the service provider. A transaction record is then written to an account transactions file of the service provider, thereby triggering execution of an accounting program for posting the order information to the user's account and to records of the service provider. The updated order information may then be outputted to the user.

Abstract: A method and computer-readable medium for managing an account balance of a user via remote connection to an account database system of a service provider are provided. According to the method, payment information is received from the user via the remote connection for a selected invoice of an account of the user. The payment information is outputted to an external payment service for settlement of payment, and, if the settlement is successful, authorization and settlement data are received from the external payment service and written to a payment file of the user. A transaction record is then written to an account transactions file of the service provider, thereby triggering execution of an accounting program for posting the authorization and settlement data to the user's account and to financial records of the service provider. The updated invoice information may then be outputted to the user.

Abstract: A probe card for production testing of semiconductor imaging die includes a stiffener supported on a bottom side of the probe card. The top of the stiffener is substantially flush with a top surface of the probe card. A light passage through the stiffener features non-reflective surfaces. Surfaces surrounding the light passage are arranged to avoid casting any shadows on the imaging die being tested. The arrangement provides a low profile probe card. A source of light used to illuminate the imaging die through the light passage can be placed close to the imaging device under test, providing few false negatives and more consistent results from wafer to wafer.

Abstract: A probe card for production testing of semiconductor imaging die includes a stiffener supported on a bottom side of the probe card. The top of the stiffener is substantially flush with a top surface of the probe card. A light passage through the stiffener features non-reflective surfaces. Surfaces surrounding the light passage are arranged to avoid casting any shadows on the imaging die being tested. The arrangement provides a low profile probe card. A source of light used to illuminate the imaging die through the light passage can be placed close to the imaging device under test, providing few false negatives and more consistent results from wafer to wafer.

Abstract: A barrier for retarding fire comprises water-permeable fabric for covering a substantial area, the fabric having at least 9 pockets per square foot, each pocket having a volumetric capacity of between about 0.03 cubic inches and about 17 cubic inches, wherein substantially all of the pockets contain between about 0.01 and about 2 grams of superabsorbent polymer per cubic inch of volumetric capacity of the pockets.