Patents by Inventor Deborah R. Gill

Deborah R. Gill has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • RETROVIRAL VECTORS
    Publication number: 20240082327
    Abstract: The present invention relates to retroviral vectors, particularly lentiviral vectors, comprising a modified retroviral RNA sequence that is codon-substituted and comprises a reduced number of retroviral open-reading frames, and wherein the retroviral vector is pseudotyped with hemagglutinin-neuraminidase (HN) and fusion (F) proteins from a respiratory paramyxovirus, methods of making the same and uses thereof.
    Type: Application
    Filed: August 25, 2023
    Publication date: March 14, 2024
    Inventors: Deborah R. GILL, Stephen C. HYDE
  • COMBINATION TREATMENT
    Publication number: 20240024515
    Abstract: The present invention relates to combination treatments for cystic fibrosis, particularly combinations of modulators of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) and gene therapy.
    Type: Application
    Filed: April 11, 2023
    Publication date: January 25, 2024
    Inventors: Eric Alton, Jane Davies, Uta Grisenbach, Ana Sergijenko, Deborah R. Gill, Stephen C. Hyde, Christopher Boyd, Gerry McLachlan, Sebastian Kreuz, Alena Moiseenko
  • RETROVIRAL VECTORS
    Publication number: 20220273821
    Abstract: This invention relates to retroviral gene transfer vectors, particularly lentiviral vectors, pseudotyped with hemagglutinin-neuraminidase (HN) and fusion (F) proteins from a respiratory paramyxovirus, comprising a promoter and a transgene; and methods of making the same. The present invention also relates to the use of said vectors in gene therapy, particularly for the treatment of respiratory tract diseases such as Cystic Fibrosis (CF).
    Type: Application
    Filed: February 25, 2022
    Publication date: September 1, 2022
    Inventors: Deborah R. Gill, Stephen C. Hyde