Patents by Inventor Deborah Sweet

Deborah Sweet has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • FORMULATIONS OF MONOCLONAL ANTIBODIES
    Publication number: 20220204597
    Abstract: The present invention provides a formulation comprising: (i) a monoclonal antibody; and (ii) an ionic excipient; wherein the monoclonal antibody is present at a concentration of about 50 mg/ml or greater (e.g. about 50 mg/ml to about 200 mg/ml) and the ionic excipient is present at a concentration of about 50 to about 150 mM and the formulation has a pH of 5.5 to 6.5.
    Type: Application
    Filed: November 19, 2021
    Publication date: June 30, 2022
    Applicant: MEDIMMUNE LIMITED
    Inventors: Brian LOBO, Deborah Sweet GOLDBERG, Monika Sood SHARMA, Ambarish Umakant SHAH
  • PREVENTION OF PROTEIN DISULFIDE BOND REDUCTION
    Publication number: 20220098282
    Abstract: Disclosed are methods for testing the presence and/or activity of glutathione system components and thioredoxin system components during the manufacturing process of disulfide bond-containing proteins. Also disclosed are methods for mitigating reduction of disulfide bonds during the manufacturing process, and for lowering the reduction potential of disulfide bond-containing proteins. Provided are compositions, kits, and methods for mitigating reduction and diminishing reduction potential of disulfide bond-containing proteins during protein manufacturing processes.
    Type: Application
    Filed: December 8, 2021
    Publication date: March 31, 2022
    Inventors: Sanjeev AHUJA, Wai Keen CHUNG, Deborah Sweet GOLDBERG, Michael HANDLOGTEN, Someet NARANG, Brian RUSSELL, Min ZHU, Suzanne HUDAK, Kenneth HWANG, Jihong WANG
  • FORMULATIONS OF MONOCLONAL ANTIBODIES
    Publication number: 20220089713
    Abstract: The present invention provides a formulation comprising: (i) a monoclonal antibody; and (ii) an ionic excipient; wherein the monoclonal antibody is present at a concentration of about 50 mg/ml or greater (e.g. about 50 mg/ml to about 200 mg/ml) and the ionic excipient is present at a concentration of about 50 to about 150 mM and the formulation has a pH of 5.5 to 6.5.
    Type: Application
    Filed: April 7, 2021
    Publication date: March 24, 2022
    Inventors: Brian Lobo, Deborah Sweet Goldberg, Monika Sood Sharma, Ambarish Umakant Shah
  • FORMULATIONS OF MONOCLONAL ANTIBODIES
    Publication number: 20200283516
    Abstract: The present invention provides a formulation comprising: (i) a monoclonal antibody; and (ii) an ionic excipient; wherein the monoclonal antibody is present at a concentration of about 50 mg/ml or greater (e.g. about 50 mg/ml to about 200 mg/ml) and the ionic excipient is present at a concentration of about 50 to about 150 mM and the formulation has a pH of 5.5 to 6.5.
    Type: Application
    Filed: February 28, 2018
    Publication date: September 10, 2020
    Applicant: MEDIMMUNE LIMITED
    Inventors: Brian LOBO, Deborah Sweet GOLDBERG, Monika Sood SHARMA, Ambarish Umakant SHAH
  • PREVENTION OF PROTEIN DISULFIDE BOND REDUCTION
    Publication number: 20190112357
    Abstract: Disclosed are methods for testing the presence and/or activity of glutathione system components and thioredoxin system components during the manufacturing process of disulfide bond-containing proteins. Also disclosed are methods for mitigating reduction of disulfide bonds during the manufacturing process, and for lowering the reduction potential of disulfide bond-containing proteins. Provided are compositions, kits, and methods for mitigating reduction and diminishing reduction potential of disulfide bond-containing proteins during protein manufacturing processes.
    Type: Application
    Filed: May 9, 2017
    Publication date: April 18, 2019
    Inventors: Sanjeev AHUJA, Wai Keen CHUNG, Deborah Sweet GOLDBERG, Michael HANDLOGTEN, Someet NARANG, Brian RUSSELL, Min ZHU, Suzanne HUDAK, Kenneth HWANG, Jihong WANG
  • Sock
    Patent number: D848138
    Type: Grant
    Filed: January 30, 2018
    Date of Patent: May 14, 2019
    Inventor: Deborah Sweet