Abstract: Provided are materials, methods and uses for treating an ophthalmological condition such as Leber Congenital Amaurosis by administering an effective amount of an adeno-associated virus AAV2, serotype 5 (AAV 2/5) or AAV-5 comprising an expressible coding region for human RDH12.

Abstract: Provided are materials, methods and uses for treating an ophthalmological condition such as Leber Congenital Amaurosis by administering an effective amount of an adeno-associated virus AAV2, serotype 5 (AAV 2/5) or AAV-5 comprising an expressible coding region for human RDH12.

Abstract: In one embodiment, a method includes receiving data associated with an event. The method includes identifying a parameter of the event. The method also includes identifying a buffer to store the data associated with the event based on the parameter the event. The method further includes storing the data associated with the event in the buffer. The method also includes determining whether data stored in the buffer meet a predetermined condition. The method further includes sending the data in the buffer.

Abstract: A multi-fold peel-off coupon redemption card includes a plurality of coupons releasably adhered to a base with a release liner. The release liner is composed of a material, such as a dry release adhesive or evaporative adhesive, such that when a coupon is removed from the base substantially no effective adhesive remains on the removed coupon. Each coupon preferably includes promotion indicia and an electronic redemption indicia. The electronic redemption indicia is preferably printed on a face of the coupon facing the base so that each coupon can be electronically redeemed while having sufficient space for the promotion indicia on the opposite face of the coupon.

Abstract: A peel-off coupon redemption card includes a plurality of coupons releasably adhered to a base with a release liner. The release liner is composed of a material, such as a dry release adhesive or evaporative adhesive, such that when a coupon is removed from the base substantially no effective adhesive remains on the removed coupon. Each coupon preferably includes promotion indicia and an electronic redemption indicia. The electronic redemption indicia is preferably printed on a face of the coupon facing the base so that each coupon can be electronically redeemed while having sufficient space for the promotion indicia on the opposite face of the coupon.