Patents by Inventor Debra D. Pittman

Debra D. Pittman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and compositions for regulating bone and cartilage formation
    Publication number: 20030087259
    Abstract: The invention provides methods and compositions for diagnostic assays for detecting bone and cartilage formation and therapeutic methods and compositions for treating disease and disorders related to bone and cartilage formation or resorption, such as osteoporosis and bone fractions. The invention also provides therapeutic methods for diseases related to bone or cartilage formation or resorption. Methods for identifying therapeutics for such diseases are also provided.
    Type: Application
    Filed: April 18, 2002
    Publication date: May 8, 2003
    Inventors: Brian M. Clancy, Debra D. Pittman
  • Procoagulant proteins
    Patent number: 5451521
    Abstract: This invention relates to recombinant Factor VIII:c variants, methods to produce the variants and pharmaceutical compositions containing same. The variants of this invention are characterized by modification of one or more specific proteolytic cleavage sites encompassing the arginine residues at positions 226, 336, 562, 740, 776, 1313, 1648, or 1721. The variants possess similar procoagulant activity to that of human Factor VIII:c.
    Type: Grant
    Filed: December 9, 1986
    Date of Patent: September 19, 1995
    Assignee: Genetics Institute, Inc.
    Inventors: Randal J. Kaufman, Debra D. Pittman, John J. Toole, Jr.
  • Human factor VIII:c muteins
    Patent number: 5422260
    Abstract: This invention relates to recombinant Factor VIII:c variants, methods to produce the variants and pharmaceutical compositions containing same.
    Type: Grant
    Filed: May 15, 1992
    Date of Patent: June 6, 1995
    Assignee: Genetics Institute, Inc. -Legal Affairs
    Inventors: Randal J. Kaufman, Debra D. Pittman, John J. Toole