Patents by Inventor Debra Hanks

Debra Hanks has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Immunohistochemistry scoring methods and compositions
    Patent number: 10718773
    Abstract: Aspects of the present disclosure provide methods for determining the eligibility of a subject having a malignancy for treatment with an anti-PD therapeutic agent. In certain embodiments, the method includes determining, by immunohistochemistry, the number of PD-L1 positive malignant cells in a tumor tissue section as well as the number of infiltrating non-malignant cells and/or non-malignant cells of the stromal interface area. The infiltrating non-malignant cells and/or non-malignant cells of the stromal interface area are positive for a marker selected from PD-L1, CD8, CD68, and any combination thereof. Compositions and kits or performing the disclosed methods are also provided.
    Type: Grant
    Filed: February 2, 2017
    Date of Patent: July 21, 2020
    Assignee: AGILENT TECHNOLOGIES, INC.
    Inventors: Debra Hanks, Mai Nguyen, Marko Srdanov, Che Hutson
  • IMMUNOHISTOCHEMISTRY SCORING METHODS AND COMPOSITIONS
    Publication number: 20170285029
    Abstract: Aspects of the present disclosure provide methods for determining the eligibility of a subject having a malignancy for treatment with an anti-PD therapeutic agent. In certain embodiments, the method includes determining, by immunohistochemistry, the number of PD-L1 positive malignant cells in a tumor tissue section as well as the number of infiltrating non-malignant cells and/or non-malignant cells of the stromal interface area. The infiltrating non-malignant cells and/or non-malignant cells of the stromal interface area are positive for a marker selected from PD-L1, CD8, CD68, and any combination thereof. Compositions and kits or performing the disclosed methods are also provided.
    Type: Application
    Filed: February 2, 2017
    Publication date: October 5, 2017
    Inventors: Debra Hanks, Mai Nguyen, Marko Srdanov, Che Hutson