Abstract: A needle guide ensures that an angiographic needle is inserted into a patient's femoral artery at a prescribed location, angle and direction. The needle guide includes an elongated base having a recess on one end defined by a pair of projecting fingers, and a support member on the upper surface of the base adjacent to the recess. The support member has a support surface which is inclined at a prescribed angle with respect to a locating plane defined by the base. The length of the projecting fingers help position the support surface at a spaced distance from the patient's inguinal crease, while a channel in the support surface cradles and guides the angiographic needle at the prescribed angle as it is inserted into the femoral artery. The needle guide may include a second recess defined by a pair of projecting fingers at the opposite end of the base and another support member adjacent thereto.