Patents by Inventor Debra Sheldon-Heller

Debra Sheldon-Heller has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of diagnosing and treating hyperproliferative disorders
    Publication number: 20180237517
    Abstract: The invention relates to compositions and methods for diagnosing and treating hyperproliferative disorders using ligands which specifically recognize the hypusine and/or folate binding region of mature eukaryotic translation initiation factor 5A (hypusine-containing eIF-5A). The invention further relates to methods of identifying molecules which displace immunoreagents binding to mature eIF-5A. Such agents are useful for treating hyperproliferative disorders.
    Type: Application
    Filed: January 2, 2014
    Publication date: August 23, 2018
    Applicant: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: Hartmut M. Hanauske-Abel, Myung-Hee Park, Edith C. Wolff, Debra Sheldon-Heller, Bernadette M. Cracchiolo, Anthony Popowicz, Paul M. Clement
  • Methods of diagnosing and treating hyperproliferative disorders
    Publication number: 20170226201
    Abstract: The invention relates to compositions and methods for diagnosing and treating hyperproliferative disorders using ligands which specifically recognize the hypusine and/or folate binding region of mature eukaryotic translation initiation factor 5A (hypusine-containing eIF-5A). The invention further relates to methods of identifying molecules which displace immunoreagents binding to mature eIF-5A. Such agents are useful for treating hyperproliferative disorders.
    Type: Application
    Filed: January 2, 2014
    Publication date: August 10, 2017
    Applicant: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: Hartmut M. Hanauske-Abel, Myung-Hee Park, Edith C. Wolff, Debra Sheldon-Heller, Bernadette M. Cracchiolo, Anthony Popowicz, Paul M. Clement
  • Methods of diagnosing and treating hyperproliferative disorders
    Publication number: 20090253777
    Abstract: The invention relates to compositions and methods for diagnosing and treating hyperproliferative disorders using ligands which specifically recognize the hypusine and/or folate binding region of mature eukaryotic translation initiation factor 5A (hypusine-containing eIF-5A). The invention further relates to methods of identifying molecules which displace immunoreagents binding to mature eIF-5A. Such agents are useful for treating hyperproliferative disorders.
    Type: Application
    Filed: September 13, 2003
    Publication date: October 8, 2009
    Inventors: Hartmut M. Hanauske-Abel, Myung-Hee Park, Edith C. Wolff, Debra Sheldon-Heller, Bernadette M. Cracciolo, Anthony Popowicz, Paul M.J. Clement