Patents by Inventor Debrah Thompson

Debrah Thompson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS OF DETECTING DNA AND RNA IN THE SAME SAMPLE
    Publication number: 20220106640
    Abstract: The present disclosure provides methods for sequencing nucleic acid targets (e.g., both DNA and RNA co-amplified in a sample mixture, for example by using a surrogate for the RNA). Such methods can be used to determine if one or more nucleic acid targets are present in a sample.
    Type: Application
    Filed: December 2, 2019
    Publication date: April 7, 2022
    Applicant: HTG Molecular Diagnostics, Inc.
    Inventors: Debrah Thompson, Matthew Rounseville
  • METHOD OF DIRECT TARGET SEQUENCING USING NUCLEASE PROTECTION
    Publication number: 20190017112
    Abstract: The present disclosure provides methods and kits for direct sequencing of nucleic acid targets. Such methods can be used to determine if one or more nucleic acid targets are present in a sample.
    Type: Application
    Filed: February 10, 2017
    Publication date: January 17, 2019
    Applicant: HTG Molecular Diagnostics, Inc.
    Inventors: Debrah Thompson, Matthew Rounseville
  • SUBTYPING LUNG CANCERS
    Publication number: 20160019337
    Abstract: This disclosure concerns the identification of biomarkers that are characteristic of squamous or non squamous (e.g., adenocarcinoma, large cell carcinoma, carcinoid tumor, sarcomatoid carcinoma) subtypes of non small cell lung cancer (NSCLC), clinically useful NSCLC classifiers, kits and arrays for distinguishing squamous and nonsquamous NSCLC subtypes, bioinformatic methods for determining clinically useful classifiers, and methods of use of each of the foregoing.
    Type: Application
    Filed: March 3, 2014
    Publication date: January 21, 2016
    Applicant: HTG Molecular Diagnostics, Inc.
    Inventors: Christopher Roberts, Hui Wang, Zhenquiang Lu, Krishna Maddula, Sam Rua, Kevin Knapp, Byron Lawson, Debrah Thompson, Michael Hrubiak, Tyler Breedlove, Vijay Modur
  • QUANTITATIVE NUCLEASE PROTECTION ASSAY (QNPA) AND SEQUENCING (QNPS) IMPROVEMENTS
    Publication number: 20140235460
    Abstract: The present disclosure provides an improvement to quantitative Nuclease Protection Assay (qNPA) and quantitative Nuclease Protection Sequencing (qNPS) methods. The disclosed methods use nuclease protection probes (NPPs) that include 5?-end and/or 3-end flanking sequences, which provide a universal hybridization and/or amplification sequence. The disclosed methods can be used to sequence or detect target nucleic acid molecules, such as those present in fixed or insoluble samples.
    Type: Application
    Filed: May 1, 2014
    Publication date: August 21, 2014
    Applicant: HTG Molecular Diagnostics, Inc.
    Inventors: Debrah Thompson, Bruce E. Seligmann, Debra A. Gordon
  • Quantitative nuclease protection assay (QNPA) and sequencing (QNPS) improvements
    Patent number: 8741564
    Abstract: The present disclosure provides an improvement to quantitative Nuclease Protection Assay (qNPA) and quantitative Nuclease Protection Sequencing (qNPS) methods. The disclosed methods use nuclease protection probes (NPPs) that include 5?-end and/or 3-end flanking sequences, which provide a universal hybridization and/or amplification sequence. The disclosed methods can be used to sequence or detect target nucleic acid molecules, such as those present in fixed or insoluble samples.
    Type: Grant
    Filed: April 26, 2012
    Date of Patent: June 3, 2014
    Assignee: HTG Molecular Diagnostics, Inc.
    Inventors: Bruce Seligmann, Debrah Thompson, Tom Vasicek, Debra A. Gordon
  • QUANTITATIVE NUCLEASE PROTECTION ASSAY (QNPA) AND SEQUENCING (QNPS) IMPROVEMENTS
    Publication number: 20140087954
    Abstract: The present disclosure provides an improvement to quantitative Nuclease Protection Assay (qNPA) and quantitative Nuclease Protection Sequencing (qNPS) methods. The disclosed methods use nuclease protection probes (NPPs) that include 5?-end and/or 3-end flanking sequences, which provide a universal hybridization and/or amplification sequence. The disclosed methods can be used to sequence or detect target nucleic acid molecules, such as those present in fixed or insoluble samples.
    Type: Application
    Filed: April 26, 2012
    Publication date: March 27, 2014
    Applicant: HTG Molecular Diagnostics, Inc.
    Inventors: Bruce E. Seligmann, Debrah Thompson, Tom Vasicek, Debra A. Gordon