Patents by Inventor Deepa Subramanyam

Deepa Subramanyam has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Embryonic stem cell specific microRNAs promote induced pluripotency
    Patent number: 8852940
    Abstract: The methods of the present application describe that introduction of physiologically relevant miRNAs can enhance or modulate somatic cell reprogramming, generating induced pluripotent stem cells (iPS cells). These miRNAs did not further enhance reprogramming in the presence of cMyc. Furthermore, unlike previously described methods of generating iPS cells, such as through the introduction of genetic elements using viruses, the methods of the present invention reduce the risk of activating oncogenes in the iPS cells. The methods of the invention generate iPS cells that can be free of genetic modifications and thus have greater potential for use as therapeutic agents than those generated by existing methods.
    Type: Grant
    Filed: April 1, 2010
    Date of Patent: October 7, 2014
    Assignee: The Regents of the University of California
    Inventors: Robert Blelloch, Robert Laird Judson, Deepa Subramanyam, Collin Alfred Melton, Yangming Wang
  • EMBRYONIC STEM CELL SPECIFIC MICRORNAS PROMOTE INDUCED PLURIPOTENCY
    Publication number: 20120134966
    Abstract: The methods of the present application describe that introduction of physiologically relevant miRNAs can enhance or modulate somatic cell reprogramming, generating induced pluripotent stem cells (iPS cells). These miRNAs did not further enhance reprogramming in the presence of cMyc. Furthermore, unlike previously described methods of generating iPS cells, such as through the introduction of genetic elements using viruses, the methods of the present invention reduce the risk of activating oncogenes in the iPS cells. The methods of the invention generate iPS cells that can be free of genetic modifications and thus have greater potential for use as therapeutic agents than those generated by existing methods.
    Type: Application
    Filed: April 1, 2010
    Publication date: May 31, 2012
    Applicant: The Regents of the University of California
    Inventors: Robert Blelloch, Robert Laird Judson, Deepa Subramanyam, Collin Alfred Melton, Yangming Wang