Abstract: An example system for detecting stroke includes an imaging device; a microphone; and a computing device. The computing device is configured to receive a sequence of images capturing a state of a patient; analyze the sequence of images to detect one or more of limb impairment, gaze impairment, or facial palsy; and assign a respective numeric score to each of the detected one or more limb impairment, gaze impairment, or facial palsy. The computing device is also configured to receive an audio signal capturing a voice of the patient; analyze the audio signal to detect aphasia or agnosia; assign a respective numeric score to the detected aphasia or agnosia. The computing device is further configured to generate a stroke score, which is a sum of the respective numeric scores for the detected one or more of limb impairment, gaze impairment, or facial palsy and the detected aphasia or agnosia.