Patents by Inventor Deepak MISHRA

Deepak MISHRA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220404337
    Abstract: The invention relates to compositions and methods for making and use of a real-time cellular sensor. Components of a multipart enzyme are sequestered in different cellular compartments and only come together after receptor activation; a pool of substrate is made available in the cell to ensure real-time enzymatic output.
    Type: Application
    Filed: April 21, 2022
    Publication date: December 22, 2022
    Applicant: Massachusetts Institute of Technology
    Inventors: Frances Nargi, Scott Thomas Wick, Deepak Mishra
  • Publication number: 20220354345
    Abstract: A tissue-engagement member having a pair of jaws movable between a closed configuration and an open configuration, an actuator movable to shift the jaws between the closed and open configurations, and a biasing element biasing the jaws into a closed configuration. The biasing element may be provided over a portion of the tissue-engagement member. A cam mechanism may be provided in operative association with at least one of the jaws and/or the actuator. The biasing element may operatively engage at least one of the jaws and/or the actuator to actuate the cam mechanism to return the jaws to a closed configuration from an open configuration. A manipulator having an actuator-engagement element may be provided to engage an actuation element operatively associated with the actuator. The actuator-engagement element may operatively engage the actuation element in a range of orientations.
    Type: Application
    Filed: May 3, 2022
    Publication date: November 10, 2022
    Inventors: Kevin L. Bagley, Deepak Kumar Sharma, Shrikant Vasant Raut, James J. Scutti, Agrim Mishra, Nabarun Bhowmick
  • Publication number: 20220298509
    Abstract: Provided herein are sequestrons for detecting an miRNA profile indicative of a cell state and expressing an output molecule in cells having such an miRNA profile. Also provided are methods of using sequestrons provided herein.
    Type: Application
    Filed: March 22, 2022
    Publication date: September 22, 2022
    Applicant: Massachusetts Institute of Technology
    Inventors: Ron Weiss, Deepak Mishra, Erez Pery, Wenlong Xu, Lei Wang
  • Publication number: 20220064340
    Abstract: A method for forming an acrylic emulsion includes a step of forming pre-emulsion by combining a monomer composition with an amphoteric surfactant in water and then polymerizing the pre-emulsion by combining the pre-emulsion with a radical initiator in a reactor to form a reaction mixture. The monomer composition includes one or more monomers selected from the group consisting of (meth)acrylic acid monomers and (meth)acrylic monomers, and combinations thereof. An acrylic emulsion formed by the method is also provided.
    Type: Application
    Filed: August 31, 2020
    Publication date: March 3, 2022
    Inventors: Deepak MISHRA, Hemant NAIR, Niranjan GORIWALE, Jigui LI, Ming-Ren TARNG