Patents by Inventor Deepak R. Thakker

Deepak R. Thakker has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Anti-amyloid beta antibodies conjugated to sialic acid-containing molecules
    Patent number: 8323654
    Abstract: Antibody complexes including anti-A? antibodies conjugated with a sialic acid-containing molecule show improved bioavailability with no significant adverse effects on binding to amyloid beta.
    Type: Grant
    Filed: May 26, 2010
    Date of Patent: December 4, 2012
    Assignee: Medtronic, Inc.
    Inventors: Michael E. Benz, Lisa L. Shafer, Deepak R. Thakker
  • ANTI-AMYLOID BETA ANTIBODIES CONJUGATED TO SIALIC ACID-CONTAINING MOLECULES
    Publication number: 20110202000
    Abstract: Antibody complexes including anti-A? antibodies conjugated with a sialic acid-containing molecule show improved bioavailability with no significant adverse effects on binding to amyloid beta.
    Type: Application
    Filed: May 26, 2010
    Publication date: August 18, 2011
    Inventors: MICHAEL BENZ, DEEPAK R. THAKKER, LISA L. SHAFER
  • APHERESIS, ADMINISTRATION OF AGENT, OR COMBINATION THEREOF
    Publication number: 20110033463
    Abstract: A device is configured to remove a target molecule from a bodily fluid of a subject and to deliver a therapeutic agent to the subject. Such a device may be used for treatment of a disease associated with amyloid beta accumulation in the subject. Agents selected from the group consisting of an ApoE-modulating agent; a RAGE inhibitor; a ?-secretase 1 (BACE1) inhibitor; a ?-secretase inhibitor; a muscarinic receptor subtype 1 (M1) agonists; a growth factor; an enzyme capable of degrading amyloid beta; a mitochondrial antioxidant; insulin; and an inhibitor of tumor necrosis factor (TNF) may be administered directly to the central nervous system of a subject for treatment of a disease associated with amyloid beta accumulation.
    Type: Application
    Filed: August 6, 2010
    Publication date: February 10, 2011
    Applicant: MEDTRONIC, INC.
    Inventors: Deepak R. Thakker, Lisa L. Shafer