Abstract: The apparatus for deployment of an intravascular therapeutic device, includes an elongated, flexible pusher member and a therapeutic device connected to a severable portion of a first connector member mounted to the flexible pusher member with an elongated second connector member connected to the therapeutic device. The first connector member or second connector member may be capable of being broken by heat, and a heat source is provided for heating and breaking the first connector member or the second connector member to release the therapeutic device.

Abstract: A method and system for reducing storage requirements and speeding up storage operations by reducing the storage of redundant data includes receiving a request that identifies one or more data objects to which to apply a storage operation. For each data object, the storage system determines if the data object contains data that matches another data object to which the storage operation was previously applied. If the data objects do not match, then the storage system performs the storage operation in a usual manner. However, if the data objects do match, then the storage system may avoid performing the storage operation.

Abstract: A method and system for reducing storage requirements and speeding up storage operations by reducing the storage of redundant data includes receiving a request that identifies one or more data objects to which to apply a storage operation. For each data object, the storage system determines if the data object contains data that matches another data object to which the storage operation was previously applied. If the data objects do not match, then the storage system performs the storage operation in a usual manner. However, if the data objects do match, then the storage system may avoid performing the storage operation.

Abstract: A proxy mobile station for retransmitting reverse channel signals from a mobile station to a base station of a wireless network. The proxy mobile station comprises: 1) a controller for receiving reverse channel data to be transmitted to the base station and transmitting the reverse channel data using an assigned mobile station identifier associated with the mobile station; and 2) a radio frequency transceiver for up-converting the encoded reverse channel data for transmission to the base station. The assigned mobile station is modifiable and may be modified by an external control device.

Abstract: A method and system for reducing storage requirements and speeding up storage operations by reducing the storage of redundant data includes receiving a request that identifies one or more data objects to which to apply a storage operation. For each data object, the storage system determines if the data object contains data that matches another data object to which the storage operation was previously applied. If the data objects do not match, then the storage system performs the storage operation in a usual manner. However, if the data objects do match, then the storage system may avoid performing the storage operation.

Abstract: A method and system for creating an index of content without interfering with the source of the content includes an offline content indexing system that creates an index of content from an offline copy of data. The system may associate additional properties or tags with data that are not part of traditional indexing of content, such as the time the content was last available or user attributes associated with the content. Users can search the created index to locate content that is no longer available or based on the associate attributes.

Abstract: A generic RAID engine system accepts an access request, accepts a metadata input comprising a layout description and, optionally, a plurality of resource optimization objectives, accepts a dynamic input comprising a dynamic state of an I/O stack comprising the generic RAID engine and a fault configuration of a plurality of storage devices in the I/O stack, and accepts RAID code input comprising information about the RAID code used by the I/O stack. The metadata input, the dynamic input, and the RAID code input are utilized to transform the access request into individual device reads and individual device writes such that RAID code relationships for the storage devices are maintained at all times. An optional optimizer module selects strategies that meet the resource optimization objectives.

Abstract: Antibody complexes including anti-A? antibodies conjugated with a sialic acid-containing molecule show improved bioavailability with no significant adverse effects on binding to amyloid beta.

Abstract: The embodiments of the invention provide a method, apparatus, etc. for a cache arrangement for improving RAID I/O operations. More specifically, a method begins by partitioning a data object into a plurality of data blocks and creating one or more parity data blocks from the data object. Next, the data blocks and the parity data blocks are stored within storage nodes. Following this, the method caches data blocks within a partitioned cache, wherein the partitioned cache includes a plurality of cache partitions. The cache partitions are located within the storage nodes, wherein each cache partition is smaller than the data object. Moreover, the caching within the partitioned cache only caches data blocks in parity storage nodes, wherein the parity storage nodes comprise a parity storage field. Thus, caching within the partitioned cache avoids caching data blocks within storage nodes lacking the parity storage field.

Abstract: A method and system for reducing storage requirements and speeding up storage operations by reducing the storage of redundant data includes receiving a request that identifies one or more data objects to which to apply a storage operation. For each data object, the storage system determines if the data object contains data that matches another data object to which the storage operation was previously applied. If the data objects do not match, then the storage system performs the storage operation in a usual manner. However, if the data objects do match, then the storage system may avoid performing the storage operation.

Abstract: A method and system for creating an index of content without interfering with the source of the content includes an offline content indexing system that creates an index of content from an offline copy of data. The system may associate additional properties or tags with data that are not part of traditional indexing of content, such as the time the content was last available or user attributes associated with the content. Users can search the created index to locate content that is no longer available or based on the associate attributes.

Abstract: A device is configured to remove a target molecule from a bodily fluid of a subject and to deliver a therapeutic agent to the subject. Such a device may be used for treatment of a disease associated with amyloid beta accumulation in the subject. Agents selected from the group consisting of an ApoE-modulating agent; a RAGE inhibitor; a ?-secretase 1 (BACE1) inhibitor; a ?-secretase inhibitor; a muscarinic receptor subtype 1 (M1) agonists; a growth factor; an enzyme capable of degrading amyloid beta; a mitochondrial antioxidant; insulin; and an inhibitor of tumor necrosis factor (TNF) may be administered directly to the central nervous system of a subject for treatment of a disease associated with amyloid beta accumulation.

Abstract: A process for the preparation of an alkali metal salt of 4-chloro-4?-hydroxy benzophenone including the steps of (a) preparing purified 4-chloro-4?-hydroxy benzophenone by a process including distilling under reduced pressure a liquid containing 4-chloro-4?-hydroxy benzophenone and a solvent selected from diphenyl sulphone, diphenylene sulphone, benzophenone and dichlorobenzophenone, and then (b) preparing the alkali metal salt of thus purified 4-chloro-4?-hydroxy benzophenone by the reaction of the purified 4-chloro-4?-hydroxy benzophenone with a stoichiometric excess of at least one alkali metal base. There is also described a polymerization process using the alkali metal salt to yield PEK with high inherent viscosity and improved mechanical and thermal properties.

Abstract: A method and system for creating an index of content without interfering with the source of the content includes an offline content indexing system that creates an index of content from an offline copy of data. The system may associate additional properties or tags with data that are not part of traditional indexing of content, such as the time the content was last available or user attributes associated with the content. Users can search the created index to locate content that is no longer available or based on the associate attributes.

Abstract: Described in detail herein are systems and methods for single instancing blocks of data in a data storage system. For example, the data storage system may include multiple computing devices (e.g., client computing devices) that store primary data. The data storage system may also include a secondary storage computing device, a single instance database, and one or more storage devices that store copies of the primary data (e.g., secondary copies, tertiary copies, etc.). The secondary storage computing device receives blocks of data from the computing devices and accesses the single instance database to determine whether the blocks of data are unique (meaning that no instances of the blocks of data are stored on the storage devices). If a block of data is unique, the single instance database stores it on a storage device. If not, the secondary storage computing device can avoid storing the block of data on the storage devices.

Abstract: A caster assembly includes a primary wheel and a secondary wheel. As the caster assembly is rolled against and over an obstacle threshold, the secondary wheel is positioned to contact the obstacle threshold first. As the caster assembly begins to roll over the threshold, the secondary wheel lifts the caster assembly part way. As the caster assembly continues to roll over the threshold, the primary wheel contacts the threshold and lifts the caster assembly over the obstacle threshold. One or more secondary or primary wheels may be used. The secondary wheel or wheels may be positioned to remain within a sweep volume of the primary wheel as the caster assembly swivels around a caster swivel axis.

Abstract: The apparatus for deployment of an intravascular therapeutic device, includes an elongated, flexible pusher member and a therapeutic device connected to a severable portion of a first connector member mounted to the flexible pusher member with an elongated second connector member connected to the therapeutic device. The first connector member or second connector member may be capable of being broken by heat, and a heat source is provided for heating and breaking the first connector member or the second connector member to release the therapeutic device.

Abstract: Described are systems and methods for storing a variable number of instances of data objects (e.g., 1, 2, 3, or up to N-1 instances, where N is the number of instances of the data object included in primary data) in secondary storage across a data storage network. In some examples, a system for storing a variable number of instances of data objects includes, one or more computing devices storing a set of data objects and multiple storage devices distinct from the one or more computing devices. Each of the multiple storage devices is configured to store at least a single instance of a data object. The system also includes a database configured to store information associated with the data objects. This information includes substantially unique identifiers for the data objects and, for each of the data objects, a number of instances of the data object stored on the multiple storage devices.

Abstract: A fault-tolerant and efficient way of deducing a set of inconsistent stripes for a network RAID protocol, wherein clients forward input/output (I/O) to a particular controller device called the coordinator, which executes RAID logic and which sends out device IOs to the relevant storage devices. If the coordinator fails then a new coordinator reconstructs its state from the storage devices.

Abstract: Shear-thinning ethylene/?-olefin and ethylene/?-olefin/diene monomer interpolymers that do not include a traditional branch-inducing monomer such as norbornadiene are prepared at an elevated temperature in an atmosphere that has little or no hydrogen using a constrained geometry complex catalyst and an activating cocatalyst.