Patents by Inventor Deepali Sawant

Deepali Sawant has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MESOTHELIN-TARGETED CD40 AGONISTIC MULTISPECIFIC ANTIBODY CONSTRUCTS FOR THE TREATMENT OF SOLID TUMORS
    Publication number: 20240150481
    Abstract: The present invention relates to a human agonistic CD40 multispecific antibody construct for treatment of solid tumors by engineering a molecule that specifically targets the CD40 pathway on tumor-associated APCs, without systemic CD40 activation.
    Type: Application
    Filed: January 19, 2024
    Publication date: May 9, 2024
    Inventors: Xin YU, Jackson EGEN, Fernando GARCES, Shunsuke TAKENAKA, AeRyon KIM, Deepali SAWANT
  • Mesothelin-targeted CD40 agonistic multispecific antibody constructs for the treatment of solid tumors
    Patent number: 11926672
    Abstract: The present invention relates to a human agonistic CD40 multispecific antibody construct for treatment of solid tumors by engineering a molecule that specifically targets the CD40 pathway on tumor-associated APCs, without systemic CD40 activation.
    Type: Grant
    Filed: December 18, 2020
    Date of Patent: March 12, 2024
    Assignee: Amgen Inc.
    Inventors: Xin Yu, Jackson Egen, Fernando Garces, Shunsuke Takenaka, AeRyon Kim, Deepali Sawant
  • MESOTHELIN-TARGETED CD40 AGONISTIC MULTISPECIFIC ANTIBODY CONSTRUCTS FOR THE TREATMENT OF SOLID TUMORS
    Publication number: 20210347905
    Abstract: The present invention relates to a human agonistic CD40 multispecific antibody construct for treatment of solid tumors by engineering a molecule that specifically targets the CD40 pathway on tumor-associated APCs, without systemic CD40 activation.
    Type: Application
    Filed: December 18, 2020
    Publication date: November 11, 2021
    Inventors: Xin YU, Jackson EGEN, Fernando GARCES, Shunsuke TAKENAKA, AeRyon KIM, Deepali SAWANT
  • METHODS FOR SCREENING Th2 INFLAMMATORY DISEASES
    Publication number: 20130065972
    Abstract: The present invention provides a method for screening for a Th2 inflammatory disease in a subject comprising the steps of: assaying a miR-21 expression level in a biological sample from the subject, and comparing the miR-21 expression level in the biological sample from the subject to the miR-21 expression level in a control, wherein an increase in the miR-21 expression level in the biological sample from the subject compared to the miR-21 expression level in the control indicates the presence of Th2 inflammatory disease in the subject.
    Type: Application
    Filed: September 7, 2012
    Publication date: March 14, 2013
    Applicant: Indiana University Research and Technology Corporation
    Inventors: Alexander L. Dent, Deepali Sawant