Patents by Inventor Deepti Parashar

Deepti Parashar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • RNAi agent for inhibition of Chikungunya virus
    Patent number: 9574195
    Abstract: Provided herein are RNAi agents for inhibition of Chikungunya virus. The present disclosure provides RNAi agents for inhibition of Chikungunya virus, particularly by targeting the E2 gene and nsP1 gene or both of the Chikungunya virus; the RNAi agents comprising of the entire nucleotide sequence set forth is SEQ ID 1 or SEQ ID 5 or combination thereof; or comprising of 15 or more contiguous nucleotides as set forth is SEQ ID 1 or SEQ ID 5 or combination thereof along with the addition nucleotides from the contiguous region of the E2 and nsP1 target gene. The invention further provides a RNAi composition for reducing the E2 protein and nsP1 protein level of Chikungunya virus and inhibition of Chikungunya virus replication. The combination of RNAi agents provides an excellent therapeutic composition for treatment of Chikungunya virus infection.
    Type: Grant
    Filed: July 2, 2014
    Date of Patent: February 21, 2017
    Assignee: Indian Council of Medical Research
    Inventors: Deepti Parashar, Vidya Avinash Arankalle, Mandar Satish Paingankar, Satyendra Kumar, Mangesh Damodar Gokhale, Sudeep Balan Anakkathil, Sapna Shinde
  • RNAi Agent for Inhibition of Chikungunya Virus
    Publication number: 20160145621
    Abstract: Provided herein are RNAi agents for inhibition of Chikungunya virus. The present disclosure provides RNAi agents for inhibition of Chikungunya virus, particularly by targeting the E2 gene and nsP1 gene or both of the Chikungunya virus; the RNAi agents comprising of the entire nucleotide sequence set forth is SEQ ID 1 or SEQ ID 5 or combination thereof; or comprising of 15 or more contiguous nucleotides as set forth is SEQ ID 1 or SEQ ID 5 or combination thereof along with the addition nucleotides from the contiguous region of the E2 and nsP1 target gene. The invention further provides a RNAi composition for reducing the E2 protein and nsP1 protein level of Chikungunya virus and inhibition of Chikungunya virus replication. The combination of RNAi agents provides an excellent therapeutic composition for treatment of Chikungunya virus infection.
    Type: Application
    Filed: July 2, 2014
    Publication date: May 26, 2016
    Inventors: Deepti Parashar, A. Vidya Arankalle, S. Mandar Paingankar, Satyendra Kumar, D. Mangesh Gokhale, B. A. Sudeep, S. Sapna Shinde