Patents by Inventor Dehua Liu
Dehua Liu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 11959866Abstract: A live flaw detection system for a multi-bundled conductor splicing sleeve and an application method thereof are disclosed. The system includes an upper apparatus and a lower apparatus, where the upper apparatus includes an unmanned aerial vehicle and an industrial X-ray machine, and a laser sensor, and the lower apparatus includes a press plate frame apparatus, vertical screw slide table modules, a horizontal screw slide table module, a projection imager, and a linear retractable apparatus. The unmanned aerial vehicle functions as a power apparatus that controls the system to be online or offline, the industrial X-ray machine is configured to perform ray flaw detection on each splicing sleeve, the laser sensor is configured to guide the unmanned aerial vehicle to land the lower apparatus on splicing sleeves accurately, and the press plate frame apparatus is configured to fixedly clamp the splicing sleeves.Type: GrantFiled: May 9, 2022Date of Patent: April 16, 2024Assignees: STATE GRID HUNAN ELECTRIC COMPANY LIMITED, STATE GRID HUNAN EXTRA HIGH VOLTAGE TRANSMISSION COMPANY, STATE GRID CORPORATION OF CHINAInventors: Dehua Zou, Shasha Peng, Zhipeng Jiang, Zhenyu Wang, Bocheng Li, Qiaosha Xiao, Yurong Xu, Zhenyu Chen, Wenyuan Zeng, Zhiguo Liu
-
Publication number: 20240115575Abstract: A pharmaceutical composition containing multi-target protein kinase inhibitor compounds, and the use thereof. The pharmaceutical composition contains compounds shown in formula II and formula A or formula B as active ingredients, and an excipient. The pharmaceutical composition has the characteristics of a simple preparation method, a smooth preparation process and suitability for industrial production. Moreover, an oral preparation prepared from the pharmaceutical composition, especially an oral solid preparation, has advantageous preparation properties such as dissolution rate and content uniformity, and excellent stability; and same is suitable for use and storage as a medicine.Type: ApplicationFiled: December 30, 2021Publication date: April 11, 2024Inventors: Cuiyan Liu, Jing Bai, Shilong Wen, Na Liu, Cong Gu, Dehua Ji
-
Patent number: 11951120Abstract: This invention relates to the fields of mRNA vaccines, mRNA therapy, and gene therapy and specifically to the use of gene expression vectors or PCR amplicons containing various 5?UTR sequences followed by coding sequences for in vitro and in vivo production of mRNA or proteins of interest.Type: GrantFiled: December 7, 2022Date of Patent: April 9, 2024Inventors: Jaewoo Lee, Dehua Wang, Xiaoyao Hao, Yue Gao, Jie Liu, Shan He, Ting He, Dan Tse
-
Patent number: 11764460Abstract: Provided are a wearable device, comprising: a metal frame, a gap between the metal frame and a mainboard of the wearable device forming an antenna of the wearable device; and a metal bezel, the metal bezel and the metal frame being electrically connected to each other through a plurality of connectors, a distance between any adjacent two of the connectors along a first direction being less than ¼ of a wavelength corresponding to a maximum operating frequency of one or more antennas of the wearable device, and the first direction being a peripheral direction of the metal frame.Type: GrantFiled: November 18, 2022Date of Patent: September 19, 2023Assignee: Anhui Huami Information Technology Co., Ltd.Inventors: Anping Zhao, Dehua Liu
-
Publication number: 20230082798Abstract: Provided are a wearable device, comprising: a metal frame, a gap between the metal frame and a mainboard of the wearable device forming an antenna of the wearable device; and a metal bezel, the metal bezel and the metal frame being electrically connected to each other through a plurality of connectors, a distance between any adjacent two of the connectors along a first direction being less than ¼ of a wavelength corresponding to a maximum operating frequency of one or more antennas of the wearable device, and the first direction being a peripheral direction of the metal frame.Type: ApplicationFiled: November 18, 2022Publication date: March 16, 2023Inventors: Anping Zhao, Dehua Liu
-
Patent number: 11542533Abstract: Provided is a method for producing 1,3-propanediol by means of fermentation of a recombinant microorganism. First, a recombinant microorganism is provided; the recombinant microorganism can overexpress acetyl-CoA carboxylase genes: accBC and accDA, a malonyl-CoA synthetase gene: mcr, a 3-hydroxypropionyl-CoA synthetase gene: pcs, a 3-hydroxypropionyl-CoA reductase gene: pduP, and a 1,3-propanediol reductase gene: yqhD. The recombinant microorganism is subjected to fermentation culture in a flask or fermentor using glucose ad as raw material to obtain the 1,3-propanediol. The recombinant microorganism can utilize low-cost glucose, sucrose, molasses, xylose and the like as raw material in the fermentation process, without additional expensive vitamin B12. Thus, cost of the production is significantly reduced, and there is a promising prospect in market.Type: GrantFiled: July 17, 2018Date of Patent: January 3, 2023Assignee: Tsinghua UniversityInventors: Zhen Chen, Dehua Liu
-
Patent number: 11530150Abstract: The invention provides a method for preparing drinking weak alkali water and strontium-rich electrolyte raw water from distilled water obtained in the process of producing salt from well and mine brine, which comprises procedures of pressure reduction treatment, primary filtration, membrane separation treatment, activated carbon adsorption treatment, secondary filtration treatment, sterilization and disinfection treatment and the like on the salt-making distilled water in sequence so as to remove insoluble solid impurities, sulfides, microorganisms and other substances in the raw water, and separate or enrich ions, thereby preparing the weak alkali water suitable for drinking and the strontium-rich electrolyte raw water capable of being used for functional beverage production. The method provided by the invention can not only realize the comprehensive utilization of resources, but also obtain new products, significantly improving the economical efficiency of the process.Type: GrantFiled: October 22, 2020Date of Patent: December 20, 2022Assignees: TSINGHUA UNIVERSITY, SICHUAN ZIGONG CHI YU SALT PRODUCTCO., LTD.Inventors: Xuebing Zhao, Dehua Liu, Ziyuan Zhou, Lingmei Dai, Chenghua Zou
-
Patent number: 11512333Abstract: A method for producing ectoine by fermenting recombinant Corynebacterium glutamicum. The recombinant Corynebacterium glutamicum is obtained by overexpressing, in Corynebacterium glutamicum, an aspartokinase gene lysC of which feedback inhibition is relieved, then replacing the promoter of the dihydrodipicolinate synthase in the recombinant bacterium to attenuate the activity of the dihydropyrimidine dicarboxylic acid synthase, and then transforming the recombinant bacterium with the ectoine synthetic path related gene ectABC. The recombinant Corynebacterium glutamicum can be fermented using different cheap raw materials under a low salt condition to produce ectoine, and use cheap corn slurry instead of expensive yeast powder as a nutritional component, so as to further reduce the costs of the raw materials. In addition, the recombinant Corynebacterium glutamicum solves the biosafety problem, simplifies the post-extraction process, and has a good market application prospect.Type: GrantFiled: November 30, 2017Date of Patent: November 29, 2022Assignee: Beijing KansenBio Technology Ltd.Inventors: Zhen Chen, Dehua Liu
-
Patent number: 11435584Abstract: Systems and methods providing optical structures providing a large field of view (FOV) for personal portable displays are described. An optical structure of embodiments comprises a catadioptric optical configuration configured to produce a magnified curved intermediate image, wherein the magnified curved intermediate image is furthered magnified with proper reflection angle and transmitted to viewer's eye. The catadioptric optical configuration may comprise two curved mirrors and a polarization prism. Optical structures comprising such catadioptric optical configurations may utilize relatively small sized image sources to produce a large FOV. Such optical structures are well suited for use in large FOV optical see through (OST) head-mounted displays (HMDs).Type: GrantFiled: March 13, 2019Date of Patent: September 6, 2022Assignee: Hong Kong Applied Science and Technology Research Institute Co., Ltd.Inventors: Dehua Liu, Chun Yip Wong, Kin Lung Chan
-
Publication number: 20220112471Abstract: Disclosed is an NADH-dependent amino acid dehydrogenase and an application thereof in increasing lysine yield. The amino acid dehydrogenases are aspartate dehydrogenase derived from Pseudomonas aeruginos, aspartate semialdehyde dehydrogenase derived from Tistrella mobilis, dihydropyridine dicarboxylic acid reductase derived from Mycobacterium tuberculosis, and diaminopimelate dehydrogenase derived from Tepidanaerobacter acetatoxydans. The amino acid sequences thereof are as shown in SEQ ID NOs: 1, 3, 5, and 7, respectively. NADH or both NADH and NADPH can be used as co-factors of the amino acid dehydrogenase to synthesize lysine, thereby reducing the demand for NADPH in the cell, and significantly increasing the production of lysine or pentanediamine.Type: ApplicationFiled: August 20, 2019Publication date: April 14, 2022Applicant: TSINGHUA UNIVERSITYInventors: Zhen CHEN, Dehua LIU
-
Patent number: 11034984Abstract: Provided in the present invention is a method for improving the yield of enzymatic preparation of biodiesel from greases, comprising: during enzymatic reaction of short-chain alcohols with greases to prepare biodiesel, introducing online dehydration steps, which lead the volatile gases in the enzyme reactor to enter into the low-temperature absorption tank, and the dehydrated gases flow back into the enzyme reactor. The formation of gas-circulation can constantly bring the moisture inside the enzyme reactor out.Type: GrantFiled: January 28, 2014Date of Patent: June 15, 2021Assignees: Tsinghua University, Beijing Cenway Bio-energy Technology Co., LtdInventors: Dehua Liu, Wei Du, Luole Zhu, Jianchun Yang
-
Publication number: 20210123079Abstract: Provided is a method for producing 1,3-propanediol by means of fermentation of a recombinant microorganism. First, a recombinant microorganism is provided; the recombinant microorganism can overexpress acetyl-CoA carboxylase genes: accBC and accDA, a malonyl-CoA synthetase gene, mcr, a 3-hydroxypropionyl-CoA synthetase gene: pcs, a 3-hydroxypropionyl-CoA reductase gene: pduP, and a 1,3-propanediol reductase gene: yqhD. The recombinant microorganism is subjected to fermentation culture in a flask or ferment or using glucose ad as raw material to obtain the 1,3-propanediol. The recombinant microorganism can utilize low-cost glucose, sucrose, malasses, xylose and the like as raw material in the fermentation process, without additional expensive vitamin B12. Thus, cost of the production is significantly reduced, and there is a promising prospect in market.Type: ApplicationFiled: July 17, 2018Publication date: April 29, 2021Inventors: Zhen Chen, Dehua Liu
-
Publication number: 20210114910Abstract: The invention provides a method for preparing drinking weak alkali water and strontium-rich electrolyte raw water from distilled water obtained in the process of producing salt from well and mine brine, which comprises procedures of pressure reduction treatment, primary filtration, membrane separation treatment, activated carbon adsorption treatment, secondary filtration treatment, sterilization and disinfection treatment and the like on the salt-making distilled water in sequence so as to remove insoluble solid impurities, sulfides, microorganisms and other substances in the raw water, and separate or enrich ions, thereby preparing the weak alkali water suitable for drinking and the strontium-rich electrolyte raw water capable of being used for functional beverage production. The method provided by the invention can not only realize the comprehensive utilization of resources, but also obtain new products, significantly improving the economical efficiency of the process.Type: ApplicationFiled: October 22, 2020Publication date: April 22, 2021Inventors: Xuebing ZHAO, Dehua LIU, Ziyuan ZHOU, Lingmei DAI, Chenghua ZOU
-
Publication number: 20210114909Abstract: The invention provides a method for preparing strontium-rich mineral water from distilled water obtained in the salt production process from brine, which comprises the following steps: carrying out aeration pretreatment on the salt-making distilled water to obtain pretreated distilled water, and further performing sand filtration, ion exchange, activated carbon, membrane filtration and sterilization and disinfection treatment on the pretreated distilled water to obtain the drinking strontium-rich mineral water with the strontium element content of more than 0.4 mg/L.Type: ApplicationFiled: October 22, 2020Publication date: April 22, 2021Inventors: Xuebing ZHAO, Dehua LIU, Ziyuan ZHOU, Lingmei DAI, Chenghua ZOU
-
Publication number: 20200292816Abstract: Systems and methods providing optical structures providing a large field of view (FOV) for personal portable displays are described. An optical structure of embodiments comprises a catadioptric optical configuration configured to produce a magnified curved intermediate image, wherein the magnified curved intermediate image is furthered magnified with proper reflection angle and transmitted to viewer's eye. The catadioptric optical configuration may comprise two curved mirrors and a polarization prism. Optical structures comprising such catadioptric optical configurations may utilize relatively small sized image sources to produce a large FOV. Such optical structures are well suited for use in large FOV optical see through (OST) head-mounted displays (HMDs).Type: ApplicationFiled: March 13, 2019Publication date: September 17, 2020Inventors: Dehua Liu, Chun Yip Wong, Kin Lung Chan
-
Publication number: 20200224233Abstract: A method for producing ectoine by fermenting recombinant Corynebacterium glutamicum. The recombinant Corynebacterium glutamicum is obtained by overexpressing, in Corynebacterium glutamicum, an aspartokinase gene lysC of which feedback inhibition is relieved, then replacing the promoter of the dihydrodipicolinate synthase in the recombinant bacterium to attenuate the activity of the dihydropyrimidine dicarboxylic acid synthase, and then transforming the recombinant bacterium with the ectoine synthetic path related gene ectABC. The recombinant Corynebacterium glutamicum can be fermented using different cheap raw materials under a low salt condition to produce ectoine, and use cheap corn slurry instead of expensive yeast powder as a nutritional component, so as to further reduce the costs of the raw materials. In addition, the recombinant Corynebacterium glutamicum solves the biosafety problem, simplifies the post-extraction process, and has a good market application prospect.Type: ApplicationFiled: November 30, 2017Publication date: July 16, 2020Inventors: Zhen Chen, Dehua Liu
-
Publication number: 20200187536Abstract: The present invention provides table salts. The said table salts contains 50 to 600 mg/kg of strontium. The strontium-rich table salts provided by the present invention has significantly higher strontium content than traditional common table salts. As one of the essential trace elements, strontium plays an important role in human health. The said table salts provided by the present invention are rich in strontium, which can be assimilated by human body during taking the said table salts. Moreover, the strontium content in the table salts provided by the present invention ranges from 50 to 600 mg/kg, which enables human body to get enough strontium to meet human needs when taking normal amount of the said table salts daily.Type: ApplicationFiled: March 19, 2018Publication date: June 18, 2020Inventors: Xuebing ZHAO, Dehua LIU, Lingmei DAI, Chenghua ZOU, Guilan YU
-
Patent number: 10246644Abstract: The present invention provides a method for preparing biodiesel, comprising: adding oil and fat, short-chain alcohol, water, and liquid lipase into a single-stage or multi-stage enzyme reactor; then separating the reaction fluid into an enzyme-containing heavy phase and a light phase; recovering and reusing the enzyme in the heavy phase; using the light phase for subsequent conversion by immobilized lipase; flowing the light phase and the short-chain alcohol into single-stage or multi-stage enzyme reactor containing an immobilized lipase; performing online dehydration during the whole reaction process or part of the reaction process.Type: GrantFiled: November 29, 2011Date of Patent: April 2, 2019Assignee: Tsinghua UniversityInventors: Wei Du, Dehua Liu, Luole Zhu
-
Patent number: 9249437Abstract: Disclosed is a process for preparing biodiesel from renewable oil and fat catalyzed by lipase with online dehydration. The method uses a short chain alcohol ROH as an acyl-acceptor, and utilizes a lipase as the catalyst to catalyze transesterification reaction of oil and fat feedstock with said short chain alcohol, so as to synthesize biodiesel; and online dehydration with a membrane or a molecular sieve is carried out during the whole process or part of the reaction process. Such online dehydration process greatly simplifies the operation procedure, and provides good economic and environmental benefits.Type: GrantFiled: November 4, 2011Date of Patent: February 2, 2016Assignee: Tsinghua UniversityInventors: Dehua Liu, Wei Du, Xuebing Zhao, Luole Zhu
-
Publication number: 20150353969Abstract: Provided in the present invention is a method for improving the yield of enzymatic preparation of biodiesel from greases, comprising: during enzymatic reaction of short-chain alcohols with greases to prepare biodiesel, introducing online dehydration steps, which lead the volatile gases in the enzyme reactor to enter into the low-temperature absorption tank, and the dehydrated gases flow back into the enzyme reactor. The formation of gas-circulation can constantly bring the moisture inside the enzyme reactor out.Type: ApplicationFiled: January 28, 2014Publication date: December 10, 2015Inventors: Dehua LIU, Wei DU, Luole ZHU, Jianchun YANG