Abstract: This invention involves a compound that is used for improving brain functioning and/or treatment of brain disorders, made from the following raw materials: (1) one or more medicinal herbs from borax, radix isatidis, honeysuckle, fritillaria cirrhosa D. Don and thunbergii; (2) One or more medicinal herbs from dryobalanops aromatica gaertn. f., calculus bovis, moschus moschiferus L., liquidambar orientalis mill. and gum benzoin; (3) One or more medicinal herbs from cortex phellodendri, coptis chinensis Franch, scutellaria baricalensis, radix gentianae, sophora flavescens; (4) One or more medicinal herbs from baphicacanthus Rhizome and Root, calculus bovis, indigowoad leaf, taraxacum officnala, rhizome of the manyleaf Paris, wild chrysanthemum; and the free selection of (5) Chrysanthemum, folium mori, mint, arctium lappa. This invention also includes the manufacturing method, uses, and the medicinal preparation of the above compounds.