Abstract: An optical device for conditioning a multi-channel optical signal is provided, comprising a channel separation and assembly unit and a signal processor. The signal processor comprises an optical attenuator for adjusting the power level of the signals, an optical detector for detecting the power level associated with each of the multiple channels, a reflective medium disposed between the optical attenuator and detector, and a microprocessor-based controller in electrical communication with the attenuator and detector for dynamically controlling the power distribution of the output signal.

Abstract: The present invention discloses a method and apparatus in relation to non-invasive measurement of human blood analytes such as glucose using Raman Spectroscopy. The method is intended to correct for errors associated with varying skin conditions. An approach is described for generating a skin/tissue function that accounts for light energy dissipation due to skin and tissue interferences such as color, thickness, sites, oily, turbid, and surface roughness, etc. The measured skin/tissue function is utilized to correct Raman spectra, thus removing uncertainty and ambiguity coming from skin conditions. The method comprises measuring incident broadband spectrum and diffuse reflectance spectrum, and from them calculating the skin-tissue function.

Abstract: The present invention discloses a method and apparatus and method for achieving non-invasive measurement of analytes from human and animal blood through the skin using Raman lightwave technology. The apparatus includes a confocal signal collection system that effectively reduces the interferences from out-of-focus signals. The apparatus further includes a tissue permeation unit, which controls the amount of blood in the laser tissue interaction region. The change of aggregate spectra with time is used to construct a new series of differenced spectra, from which the spectral effects from surrounding static substances are calibrated out dynamically using the data processing method described.

Abstract: The present invention discloses a method and apparatus and method for achieving non-invasive measurement of analytes from human and animal blood through the skin using Raman lightwave technology. The apparatus includes a hydraulic tissue permeation unit, which controls the amount of blood in the laser tissue interaction region. Two or more spectra are obtained at different blood levels. These spectra are used to improve the measurements.

Abstract: The present invention discloses a method and apparatus and method for achieving non-invasive measurement of analytes from human and animal blood through the skin using Raman lightwave technology. The apparatus includes a hydraulic tissue permeation unit, which controls the amount of blood in the laser tissue interaction region. Two or more spectra are obtained at different blood levels. These spectra are used to improve the measurements.

Abstract: A device for expanding the wavelength band of an optical component is disclosed. The device has a beam splitter for splitting a wavelength division multiplexed beam into two beams at a desired separation angle. An optical grating separates the two beams into spectral components for each beam. The spectral components are focused on a receiving surface. The separation angle between the two beams expands the wavelength band of the WDM signal.

Abstract: An optical device for conditioning a multi-channel optical signal is provided, comprising a channel separation and assembly unit and a signal processor. The signal processor comprises an optical attenuator for adjusting the power level of the signals, an optical detector for detecting the power level associated with each of the multiple channels, a reflective medium disposed between the optical attenuator and detector, and a microprocessor-based controller in electrical communication with the attenuator and detector for dynamically controlling the power distribution of the output signal.

Abstract: A device for expanding an operable wavelength band of an optical component is disclosed. The device has an optical grating configured to receive a wavelength division multiplexed optical signal. The optical grating is configured to separate the optical signal into two wavelength bands separated by a prescribed wavelength difference. The device has a focusing lens system to focus the two wavelength bands onto a receiving surface. The two wavelength bands are separated on the receiving surface by the prescribed wavelength difference in order to expand the wavelength band of the WDM signal.