Patents by Inventor Delbert Herald

Delbert Herald has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Crystal structures of dolastatin 16, dolamethylleuine and dolaphenvaline, and methods for preparing dolamethylleuine and dolaphenvaline
    Patent number: 9175041
    Abstract: The present invention relates to the crystal structures of dolastatin 16, dolamethylleuine and dolaphenvaline. The present invention also relates to processes for preparing dolamethylleuine and dolaphenvaline. The present invention further relates to computer readable medium with crystal structural data and/or information stored thereon.
    Type: Grant
    Filed: April 25, 2012
    Date of Patent: November 3, 2015
    Assignee: Arizona Board of Regents, a body corporate of the State of Arizona, acting for and on behalf of Arizona State University
    Inventors: George R. Pettit, Thomas Smith, Jun-Ping Xu, Delbert Herald
  • CRYSTAL STRUCTURES OF DOLASTATIN 16, DOLAMETHYLLEUINE AND DOLAPHENVALINE, AND METHODS FOR PREPARING DOLAMETHYLLEUINE AND DOLAPHENVALINE
    Publication number: 20140179897
    Abstract: The present invention relates to the crystal structures of dolastatin 16, dolamethylleuine and dolaphenvaline. The present invention also relates to processes for preparing dolamethylleuine and dolaphenvaline. The present invention further relates to computer readable medium with crystal structural data and/or information stored thereon.
    Type: Application
    Filed: April 25, 2012
    Publication date: June 26, 2014
    Inventors: George R. Pettit, Thomas Smith, Jun-Ping Xu, Delbert Herald
  • Aaptamine and isoaaptamine and structural modifications thereof
    Publication number: 20050187240
    Abstract: Disclosed herein is the isolation and elucidation of the structure of isoaptamine (2), and its conversion to numerous novel related compounds, which appear to have antimicrobial and/or cancer fighting properties. Also disclosed is the conversion of isoaaptamine (2) to the phosphate prodrug hystatin 1 (11), as well as the conversion of aaptamine to numerous compounds, including but not limited to: 9-demethyloxyaaptamine (3); 4-methylaaptamine (4); 1,4-dimethylaaptamine iodide (5); 4-N-methyl-8,9-dihydroxy-4H benzo[de][1,6]naphthyridine (7); 4-N-methyl-8 methoxy-9 hydroxy-4H benzo[de][1,6]naphthyridine (8); 1-H-Benzo[de][1-6]naphthyridinium salts (9a-c); hystatin 2 (10a); and others.
    Type: Application
    Filed: February 23, 2005
    Publication date: August 25, 2005
    Inventors: George Pettit, Delbert Herald, Holger Hoffman