Patents by Inventor Delbert Linn Harris
Delbert Linn Harris has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10004797Abstract: A method of quickly producing a vaccine for a biotype of pathogenic microorganism is described, where a nucleic acid molecule or fragment thereof is obtained from a biological sample from an animal exposed to the microorganism, a protective molecule is prepared based on the nucleic acid molecule of interest or fragment thereof, and administered to an animal which has been or is as risk of being exposed to the microorganism. A protective response to the biotype of the microorganism is obtained in the animal.Type: GrantFiled: October 23, 2012Date of Patent: June 26, 2018Assignee: Harrisvaccines, Inc.Inventors: Delbert Linn Harris, Matthew Erdman, Kurt Iver Kamrud, Jonathan Fowler Smith, John Dustin Loy, Lyric Colleen Bartholomay, Ed Scura
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Patent number: 9650634Abstract: Compositions and methods of protecting aquatic invertebrates from disease is shown. In one embodiment, dsRNA or antisense RNA to a nucleic acid molecule of the disease-causing microorganism is prepared and delivered to the animal. In another embodiment, a nucleic acid molecule of the disease-causing microorganism is delivered to the animal. In another embodiment, the RNA or nucleic acid molecule is delivered to the animal by replicon particle. In a further embodiment, the protective molecule is delivered to the digestive tract of the animal. Protection from disease is obtained.Type: GrantFiled: July 23, 2014Date of Patent: May 16, 2017Assignee: Harrisvaccines, Inc.Inventors: John Dustin Loy, Lyric Colleen Bartholomay, Delbert Linn Harris, Ed Scura, Kurt Iver Kamrud
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Publication number: 20150157703Abstract: A method of quickly producing a vaccine for a biotype of pathogenic microorganism is described, where a nucleic acid molecule or fragment thereof is obtained from a biological sample from an animal exposed to the microorganism, a protective molecule is prepared based on the nucleic acid molecule of interest or fragment thereof, and administered to an animal which has been or is as risk of being exposed to the microorganism. A protective response to the biotype of the microorganism is obtained in the animal.Type: ApplicationFiled: February 17, 2015Publication date: June 11, 2015Inventors: Delbert Linn HARRIS, Matthew ERDMAN, Kurt KAMRUD, Jonathan SMITH, John Dustin LOY, Lyric Colleen BARTHOLOMAY, Edward D. SCURA
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Publication number: 20140371295Abstract: Compositions and methods of protecting aquatic invertebrates from disease is shown. In one embodiment, dsRNA or antisense RNA to a nucleic acid molecule of the disease-causing microorganism is prepared and delivered to the animal. In another embodiment, a nucleic acid molecule of the disease-causing microorganism is delivered to the animal. In another embodiment, the RNA or nucleic acid molecule is delivered to the animal by replicon particle. In a further embodiment, the protective molecule is delivered to the digestive tract of the animal. Protection from disease is obtained.Type: ApplicationFiled: July 23, 2014Publication date: December 18, 2014Inventors: John Dustin Loy, Lyric Colleen Bartholomay, Delbert Linn Harris, Ed Scura, Kurt Iver Kamrud
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Patent number: 8828961Abstract: Compositions and methods of protecting aquatic invertebrates from disease is shown. In one embodiment, dsRNA or antisense RNA to a nucleic acid molecule of the disease-causing microorganism is prepared and delivered to the animal. In another embodiment, a nucleic acid molecule of the disease-causing microorganism is delivered to the animal. In another embodiment, the RNA or nucleic acid molecule is delivered to the animal by replicon particle. In a further embodiment, the protective molecule is delivered to the digestive tract of the animal. Protection from disease is obtained.Type: GrantFiled: October 19, 2011Date of Patent: September 9, 2014Assignee: HarrisvaccinesInventors: John Dustin Loy, Lyric Colleen Bartholomay, Delbert Linn Harris, Ed Scura, Kurt Iver Kamrud
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Patent number: 8822427Abstract: Compositions and methods of protecting aquatic invertebrates from disease is shown. In one embodiment, dsRNA or antisense RNA to a nucleic acid molecule of the disease-causing microorganism is prepared and delivered to the animal. In another embodiment, a nucleic acid molecule of the disease-causing microorganism is delivered to the animal. In another embodiment, the RNA or nucleic acid molecule is delivered to the animal by replicon particle. In a further embodiment, the protective molecule is delivered to the digestive tract of the animal. Protection from disease is obtained.Type: GrantFiled: October 23, 2012Date of Patent: September 2, 2014Assignee: HarrisvaccinesInventors: John Dustin Loy, Lyric Colleen Bartholomay, Delbert Linn Harris, Ed Scura, Kurt Iver Kamrud
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Patent number: 8771670Abstract: The invention relates to a polypeptide of a protective antigenic determinant (PAD polypeptide) of porcine reproductive and respiratory syndrome virus (PRRSV) and nucleic acids encoding a PAD polypeptide. The PAD polypeptide and nucleic acids encoding a PAD polypeptide are useful in the development of antibodies directed to PAD, vaccines effective in providing protection against PRRSV infection, and diagnostic assays detecting the presence of PAD antibodies generated by a PAD-specific vaccine. The invention also discloses methods of generating antibodies to PAD, for vaccinating a pig to provide protection from PRRSV infections, a method of preparing the vaccine, a method of treating PRRSV infections in a pig, and a method of detecting antibodies to PAD of PRRSV.Type: GrantFiled: June 26, 2012Date of Patent: July 8, 2014Assignee: Iowa State University Research Foundation, Inc.Inventors: Delbert Linn Harris, Matthew M. Erdman
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Publication number: 20130156800Abstract: The invention relates to a polypeptide of a protective antigenic determinant (PAD polypeptide) of porcine reproductive and respiratory syndrome virus (PRRSV) and nucleic acids encoding a PAD polypeptide. The PAD polypeptide and nucleic acids encoding a PAD polypeptide are useful in the development of antibodies directed to PAD, vaccines effective in providing protection against PRRSV infection, and diagnostic assays detecting the presence of PAD antibodies generated by a PAD-specific vaccine. The invention also discloses methods of generating antibodies to PAD, for vaccinating a pig to provide protection from PRRSV infections, a method of preparing the vaccine, a method of treating PRRSV infections in a pig, and a method of detecting antibodies to PAD of PRRSV.Type: ApplicationFiled: June 26, 2012Publication date: June 20, 2013Applicant: IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC.Inventors: Delbert Linn Harris, Matthew M. Erdman
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Patent number: 8241847Abstract: The invention relates to a polypeptide of a protective antigenic determinant (PAD polypeptide) of porcine reproductive and respiratory syndrome virus (PRRSV) and nucleic acids encoding a PAD polypeptide. The PAD polypeptide and nucleic acids encoding a PAD polypeptide are useful in the development of antibodies directed to PAD, vaccines effective in providing protection against PRRSV infection, and diagnostic assays detecting the presence of PAD antibodies generated by a PAD-specific vaccine. The invention also discloses methods of generating antibodies to PAD, for vaccinating a pig to provide protection from PRRSV infections, a method of preparing the vaccine, a method of treating PRRSV infections in a pig, and a method of detecting antibodies to PAD of PRRSV.Type: GrantFiled: May 18, 2010Date of Patent: August 14, 2012Assignee: Iowa State University Research Foundation, Inc.Inventors: Delbert Linn Harris, Matthew M. Erdman
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Publication number: 20120108649Abstract: Compositions and methods of protecting aquatic invertebrates from disease is shown. In one embodiment, dsRNA or antisense RNA to a nucleic acid molecule of the disease-causing microorganism is prepared and delivered to the animal. In another embodiment, a nucleic acid molecule of the disease-causing microorganism is delivered to the animal. In another embodiment, the RNA or nucleic acid molecule is delivered to the animal by replicon particle. In a further embodiment, the protective molecule is delivered to the digestive tract of the animal. Protection from disease is obtained.Type: ApplicationFiled: October 19, 2011Publication date: May 3, 2012Applicant: HARRISVACCINES, INC.Inventors: John Dustin Loy, Lyric Colleen Bartolomay, Delbert Linn Harris, Ed Scura, Kurt Iver Kamrud
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Publication number: 20120107355Abstract: A method of quickly producing a vaccine for a biotype of pathogenic microorganism is described, where a nucleic acid molecule or fragment thereof is obtained from a biological sample from an animal exposed to the microorganism, a protective molecule is prepared based on the nucleic acid molecule of interest or fragment thereof, and administered to an animal which has been or is as risk of being exposed to the microorganism. A protective response to the biotype of the microorganism is obtained in the animal.Type: ApplicationFiled: October 19, 2011Publication date: May 3, 2012Applicant: HARRISVACCINES, INC.Inventors: Delbert Linn Harris, Matthew Erdman, Kurt Iver Kamrud, Jonathan Smith, John Dustin Loy, Lyric Colleen Bartholomay, Ed Scura
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Publication number: 20110020233Abstract: The invention relates to a polypeptide of a protective antigenic determinant (PAD polypeptide) of porcine reproductive and respiratory syndrome virus (PRRSV) and nucleic acids encoding a PAD polypeptide. The PAD polypeptide and nucleic acids encoding a PAD polypeptide are useful in the development of antibodies directed to PAD, vaccines effective in providing protection against PRRSV infection, and diagnostic assays detecting the presence of PAD antibodies generated by a PAD-specific vaccine. The invention also discloses methods of generating antibodies to PAD, for vaccinating a pig to provide protection from PRRSV infections, a method of preparing the vaccine, a method of treating PRRSV infections in a pig, and a method of detecting antibodies to PAD of PRRSV.Type: ApplicationFiled: May 18, 2010Publication date: January 27, 2011Applicant: IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC.Inventors: DELBERT LINN HARRIS, MATTHEW M. ERDMAN
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Patent number: 7763428Abstract: The invention relates to a polypeptide of a protective antigenic determinant (PAD polypeptide) of porcine reproductive and respiratory syndrome virus (PRRSV) and nucleic acids encoding a PAD polypeptide. The PAD polypeptide and nucleic acids encoding a PAD polypeptide are useful in the development of antibodies directed to PAD, vaccines effective in providing protection against PRRSV infection, and diagnostic assays detecting the presence of PAD antibodies generated by a PAD-specific vaccine. The invention also discloses methods of generating antibodies to PAD, for vaccinating a pig to provide protection from PRRSV infections, a method of preparing the vaccine, a method of treating PRRSV infections in a pig, and a method of detecting antibodies to PAD of PRRSV.Type: GrantFiled: December 29, 2008Date of Patent: July 27, 2010Assignee: Iowa State University Research Foundation, Inc.Inventors: Delbert Linn Harris, Matthew M. Erdman
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Patent number: 7714101Abstract: The invention relates to a polypeptide of a protective antigenic determinant (PAD polypeptide) of porcine reproductive and respiratory syndrome virus (PRRSV) and nucleic acids encoding a PAD polypeptide. The PAD polypeptide and nucleic acids encoding a PAD polypeptide are useful in the development of antibodies directed to PAD, vaccines effective in providing protection against PRRSV infection, and diagnostic assays detecting the presence of PAD antibodies generated by a PAD-specific vaccine. The invention also discloses methods of generating antibodies to PAD, for vaccinating a pig to provide protection from PRRSV infections, a method of preparing the vaccine, a method of treating PRRSV infections in a pig, and a method of detecting antibodies to PAD of PRRSV.Type: GrantFiled: December 29, 2008Date of Patent: May 11, 2010Assignee: Iowa State University Research Foundation, Inc.Inventors: Delbert Linn Harris, Matthew M. Erdman
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Patent number: 7622254Abstract: The invention relates to a polypeptide of a protective antigenic determinant (PAD polypeptide) of porcine reproductive and respiratory syndrome virus (PRRSV) and nucleic acids encoding a PAD polypeptide. The PAD polypeptide and nucleic acids encoding a PAD polypeptide are useful in the development of antibodies directed to PAD, vaccines effective in providing protection against PRRSV infection, and diagnostic assays detecting the presence of PAD antibodies generated by a PAD-specific vaccine. The invention also discloses methods of generating antibodies to PAD, for vaccinating a pig to provide protection from PRRSV infections, a method of preparing the vaccine, a method of treating PRRSV infections in a pig, and a method of detecting antibodies to PAD of PRRSV.Type: GrantFiled: November 29, 2006Date of Patent: November 24, 2009Assignee: Iowa State University Research Foundation, Inc.Inventors: Delbert Linn Harris, Matthew M. Erdman
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Publication number: 20090148472Abstract: The invention relates to a polypeptide of a protective antigenic determinant (PAD polypeptide) of porcine reproductive and respiratory syndrome virus (PRRSV) and nucleic acids encoding a PAD polypeptide. The PAD polypeptide and nucleic acids encoding a PAD polypeptide are useful in the development of antibodies directed to PAD, vaccines effective in providing protection against PRRSV infection, and diagnostic assays detecting the presence of PAD antibodies generated by a PAD-specific vaccine. The invention also discloses methods of generating antibodies to PAD, for vaccinating a pig to provide protection from PRRSV infections, a method of preparing the vaccine, a method of treating PRRSV infections in a pig, and a method of detecting antibodies to PAD of PRRSV.Type: ApplicationFiled: December 29, 2008Publication date: June 11, 2009Applicant: IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC.Inventors: DELBERT LINN HARRIS, MATTHEW M. ERDMAN
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Publication number: 20090148475Abstract: The invention relates to a polypeptide of a protective antigenic determinant (PAD polypeptide) of porcine reproductive and respiratory syndrome virus (PRRSV) and nucleic acids encoding a PAD polypeptide. The PAD polypeptide and nucleic acids encoding a PAD polypeptide are useful in the development of antibodies directed to PAD, vaccines effective in providing protection against PRRSV infection, and diagnostic assays detecting the presence of PAD antibodies generated by a PAD-specific vaccine. The invention also discloses methods of generating antibodies to PAD, for vaccinating a pig to provide protection from PRRSV infections, a method of preparing the vaccine, a method of treating PRRSV infections in a pig, and a method of detecting antibodies to PAD of PRRSV.Type: ApplicationFiled: December 29, 2008Publication date: June 11, 2009Applicant: IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC.Inventors: DELBERT LINN HARRIS, MATTHEW M. ERDMAN