Patents by Inventor Delf Lachmund

Delf Lachmund has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Mass spectrometric method and MALDI-TOF mass spectrometer
    Patent number: 10504711
    Abstract: A number of standard methods exist for normalizing MALDI-TOF data, but they are not able to compensate adequately for the observed technical variability. The invention creates an improved normalization method for MALDI-TOF mass spectrometry data. This is achieved by an intensity profile normalization, where, by way of example, 1) Firstly, an intensity profile is formed for each individual spectrum, and this intensity profile describes the statistical distribution of the intensity values within different mass ranges; 2) Then an average reference profile is formed for an ensemble of spectra; 3) Finally, the individual spectra are transformed in such a way that their intensity profiles correspond to the reference profile.
    Type: Grant
    Filed: September 19, 2018
    Date of Patent: December 10, 2019
    Inventors: Tobias Boskamp, Delf Lachmund
  • MASS SPECTROMETRIC METHOD AND MALDI-TOF MASS SPECTROMETER
    Publication number: 20190096652
    Abstract: A number of standard methods exist for normalizing MALDI-TOF data, but they are not able to compensate adequately for the observed technical variability. The invention creates an improved normalization method for MALDI-TOF mass spectrometry data. This is achieved by an intensity profile normalization, where, by way of example, 1) Firstly, an intensity profile is formed for each individual spectrum, and this intensity profile describes the statistical distribution of the intensity values within different mass ranges; 2) Then an average reference profile is formed for an ensemble of spectra; 3) Finally, the individual spectra are transformed in such a way that their intensity profiles correspond to the reference profile.
    Type: Application
    Filed: September 19, 2018
    Publication date: March 28, 2019
    Inventors: Tobias Boskamp, Delf Lachmund