Patents by Inventor Deliang NIU

Deliang NIU has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Crystal form of 3-(4-methyl-1h-imidazol-1-yl)-5-trifluoromethylaniline monohydrochloride and use thereof
    Patent number: 11414388
    Abstract: The present invention relates to a crystal form of 3-(4-methyl-1H-imidazol-1-yl)-5-trifluoromethylaniline monohydrochloride and the use thereof. Specifically, disclosed are a crystal form A of a monohydrochloride anhydrous substance of 3-(4-methyl-1H-imidazol-1-yl)-5-trifluoromethylaniline monohydrochloride, a method for preparing the crystal form A and the use of the crystal form in the synthesis of nilotinib. The crystal form A of the present invention has good stability and purity, and can be directly used in the preparation and production of nilotinib. The method for preparing nilotinib in the present invention is easy to operate and has high industrial application value.
    Type: Grant
    Filed: April 8, 2019
    Date of Patent: August 16, 2022
    Assignees: Arizest (Shanghai) Pharmatech Co., Ltd., Jiangsu Xidi Pharmaceuticals Co., Ltd., Shanghai Acebright Pharmaceuticals Group Co., Ltd.
    Inventors: Deliang Niu, Bojun Ma, Zhanqun Zhu, Qiang Wan
  • CRYSTAL FORM OF 3-(4-METHYL-1H-IMIDAZOL-1-YL)-5-TRIFLUOROMETHYLANILINE MONOHYDROCHLORIDE AND USE THEREOF
    Publication number: 20210139433
    Abstract: The present invention relates to a crystal form of 3-(4-methyl-1H-imidazol-1-yl)-5-trifluoromethylaniline monohydrochloride and the use thereof. Specifically, disclosed are a crystal form A of a monohydrochloride anhydrous substance of 3-(4-methyl-1H-imidazol-1-yl)-5-trifluoromethylaniline monohydrochloride, a method for preparing the crystal form A and the use of the crystal form in the synthesis of nilotinib. The crystal form A of the present invention has good stability and purity, and can be directly used in the preparation and production of nilotinib. The method for preparing nilotinib in the present invention is easy to operate and has high industrial application value.
    Type: Application
    Filed: April 8, 2019
    Publication date: May 13, 2021
    Inventors: Deliang NIU, Bojun MA, Zhanqun ZHU, Qiang WAN