Abstract: Provided herein are nucleic acid interference pharmaceutical compositions, and drugs for treating colorectal cancer, gastric cancer and prostate cancer. For two targets (TGF-?1 and MyD88) related to tumor microenvironment and tumor metastasis in colorectal cancer, gastric cancer, and prostate cancer, an MyD88/TGF-?1 dual-target nucleic acid interference pharmaceutical composition (composition number STP500) is designed and selected, which includes an active ingredient and a pharmaceutically acceptable carrier. The active ingredient includes a first active ingredient capable of inhibiting and silencing the expression of the MyD88 gene and a second active ingredient capable of inhibiting and silencing the expression of TGF-?1 gene.

Abstract: Compositions and methods for development of potent siRNA therapeutics for prevention and treatment of Corona Virus (2019-nCoV; COVID-19) infections are provided. The compositions include a pharmaceutical composition comprising siRNA cocktails that target critical viral genes and pharmaceutically acceptable polymeric nanoparticle carriers and liposomal nanoparticle carriers. Administration methods for prevention and treatment are provided, including airway instillation, subcutaneous injections and nebulizer aerosolization.

Abstract: The techniques of the present disclosure provide a method of inhibiting tumor growth in a tissue of a mammal. The method includes administering to the mammal a therapeutically effective amount of a composition comprising an siRNA molecule that binds to an mRNA that codes for TGF?1 protein, an siRNA molecule that binds to an mRNA that codes for VEGFR2 protein, and a pharmaceutically acceptable carrier comprising a pharmaceutically acceptable polypeptide polymer. The techniques of the present disclosure also provide for additional methods for using this composition.

Abstract: A high-gain miniaturized antenna element includes a radiation structure and a feed support structure. The radiation structure includes a first radiator and a second radiator. The first radiator is arranged horizontally. The second radiator is formed by bending an outer edge of the first radiator downwardly. The feed support structure includes a plurality of feed support parts arranged vertically. Each feed support part is a downward extension of the first radiator.

Abstract: A 5G antenna unit includes: a feed stalk including two support plates intersected with each other; a radiation structure disposed at a first end of the feed stalk and including a radiation surface away from the first end of the feed stalk; and a feed board disposed at a second end of the feed stalk. One end of each of the two support plates adjacent to the radiation structure partially passes through the radiation surface of the radiation structure to fix and support the radiation structure. Each support plate is provided with at least two feed lines for coupling with the radiation surface. An end surface of the feed board adjacent to the feed board is provided with a feed network including a plurality of feed points. Each feed point is electrically connected to one of the feed lines to form a feeding structure including at least two feed points of the plurality of feed points.

Abstract: A 5G antenna unit includes: a feed stalk including two support plates intersected with each other; a radiation structure disposed at a first end of the feed stalk and including a radiation surface away from the first end of the feed stalk; and a feed board disposed at a second end of the feed stalk. One end of each of the two support plates adjacent to the radiation structure partially passes through the radiation surface of the radiation structure to fix and support the radiation structure. Each support plate is provided with at least two feed lines for coupling with the radiation surface. An end surface of the feed board adjacent to the feed board is provided with a feed network including a plurality of feed points. Each feed point is electrically connected to one of the feed lines to form a feeding structure including at least two feed points of the plurality of feed points.

Abstract: A high-gain miniaturized antenna element includes a radiation structure and a feed support structure. The radiation structure includes a first radiator and a second radiator. The first radiator is arranged horizontally. The second radiator is formed by bending an outer edge of the first radiator downwardly. The feed support structure includes a plurality of feed support parts arranged vertically. Each feed support part is a downward extension of the first radiator.

Abstract: An antenna assembly includes a radiation plate, a first feed board, and a second feed board. The radiation plate includes a radiation patch and a plurality of slot members, and each slot member includes a fixing groove and a guide groove communicating with the fixing groove. The first feed board includes a first fixing member at an end facing the radiation patch. The second feed board includes a second fixing member at an end facing the radiation patch, and the second feed board is compatible with the first feed board through a plug-in connection. The fixing grooves of the plurality of slot members respectively match the first fixing member and the second fixing member to realize an in-line cooperation of the radiation plate, the first feed board, and the second feed board.

Abstract: Compositions and methods for development of potent siRNA therapeutics for prevention and treatment of Corona Virus (2019-nCoV; COVID-19) infections are provided. The compositions include a pharmaceutical composition comprising siRNA cocktails that target critical viral genes and pharmaceutically acceptable polymeric nanoparticle carriers and liposomal nanoparticle carriers. Administration methods for prevention and treatment are provided, including airway instillation, subcutaneous injections and nebulizer aerosolization.