Patents by Inventor Delphine Buffet

Delphine Buffet has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MESOTHELIN-SPECIFIC BINDING CONSTRUCTS AND THEIR USE IN RADIOTHERAPY
    Publication number: 20260199536
    Abstract: The present invention relates to MSLN-specific binding constructs comprising a designed ankyrin repeat domain with binding specificity for MSLN and a chelator capable of bonding to a radionuclide, as well as to such MSLN-specific binding constructs comprising a half-life extending moiety with binding specificity for serum albumin. The invention further relates to methods of producing such radio-labelled MSLN-specific binding constructs, pharmaceutical compositions comprising such constructs, and the use of such constructs or pharmaceutical compositions in methods for treating, imaging or diagnosing diseases, such as cancer.
    Type: Application
    Filed: January 12, 2026
    Publication date: July 16, 2026
    Inventors: Delphine BUFFET, Clara DOMKE, Stefanie RIESENBERG, Amal SAIDI, Julien TORGUE, Aaron SCHATZMANN
  • FC BINDING FRAGMENTS COMPRISING AN OX40 ANTIGEN-BINDING SITE
    Publication number: 20250361312
    Abstract: The application relates to specific binding members that bind OX40. The specific binding members comprise an OX40 antigen-binding site located in a constant domain of the specific binding member and find application in the treatment of cancer and infectious diseases, for example.
    Type: Application
    Filed: May 8, 2025
    Publication date: November 27, 2025
    Applicant: INVOX PHARMA LIMITED
    Inventors: Mihriban Tuna, Miguel Gaspar, Sandra Uhlenbroich, Katy Everett, Delphine Buffet
  • Fc binding fragments comprising an OX40 antigen-binding site
    Patent number: 12297283
    Abstract: The application relates to specific binding members that bind OX40. The specific binding members comprise an OX40 antigen-binding site located in a constant domain of the specific binding member and find application in the treatment of cancer and infectious diseases, for example.
    Type: Grant
    Filed: July 12, 2019
    Date of Patent: May 13, 2025
    Assignee: INVOX PHARMA LIMITED
    Inventors: Mihriban Tuna, Miguel Gaspar, Sandra Uhlenbroich, Katy Everett, Delphine Buffet
  • FC BINDING FRAGMENTS COMPRISING AN OX40 ANTIGEN-BINDING SITE
    Publication number: 20210355228
    Abstract: The application relates to specific binding members that bind OX40. The specific binding members comprise an OX40 antigen-binding site located in a constant domain of the specific binding member and find application in the treatment of cancer and infectious diseases, for example.
    Type: Application
    Filed: July 12, 2019
    Publication date: November 18, 2021
    Applicant: F-star Beta Limited
    Inventors: Mihriban Tuna, Miguel Gaspar, Sandra Uhlenbroich, Katy Everett, Delphine Buffet