Patents by Inventor Dena Marrinucci

Dena Marrinucci has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for the detection of circulating tumor cells
    Patent number: 8445225
    Abstract: The present invention provides methods for revealing, detecting, and analyzing circulating tumor cells in the blood of a subject. Revealing detectable circulating tumor cells allows for early stage detection and diagnosis in addition to long term prognosis in subjects with cancer. Additionally, enrichment allows for robust detection and clinically meaningful analysis of low volume samples for use in clinical settings as well as innovative methods for the treatment of cancers.
    Type: Grant
    Filed: September 3, 2009
    Date of Patent: May 21, 2013
    Assignee: The Scripps Research Institute
    Inventors: Peter Kuhn, John Ho Griffin, Kelly Bethel, Dena Marrinucci
  • Method of Using Non-Rare Cells to Detect Rare Cells
    Publication number: 20120276555
    Abstract: The invention provides seminal computational approaches utilizing data from non-rare cells to detect rare cells, such as circulating tumor cells (CTCs). The invention is applicable at two distinct stages of CTC detection; the first being to make decisions about data collection parameters and the second being to make decisions during data reduction and analysis. Additionally, the invention utilizes both one and multi-dimensional parameterized data in a decision making process.
    Type: Application
    Filed: October 20, 2010
    Publication date: November 1, 2012
    Inventors: Peter Kuhn, Anand Kolatkar, Joshua Kunken, Dena Marrinucci, Xing Yang, John R. Stuelpnagel
  • METHODS FOR THE DETECTION OF CIRCULATING TUMOR CELLS
    Publication number: 20100247492
    Abstract: The present invention provides methods for revealing, detecting, and analyzing circulating tumor cells in the blood of a subject. Revealing detectable circulating tumor cells allows for early stage detection and diagnosis in addition to long term prognosis in subjects with cancer. Additionally, enrichment allows for robust detection and clinically meaningful analysis of low volume samples for use in clinical settings as well as innovative methods for the treatment of cancers.
    Type: Application
    Filed: September 3, 2009
    Publication date: September 30, 2010
    Applicant: The Scripps Research Institute
    Inventors: Peter Kuhn, John H. Griffin, Kelly Bethel, Dena Marrinucci
  • Methods for Detection of Circulating Tumor Cells and Methods of Diagnosis of Cancer in Mammalian Subject
    Publication number: 20090317836
    Abstract: Methods are provided for detecting circulating tumor cells in a mammalian subject. Methods of diagnosing cancer in a mammalian subject are provided. The methods of detection or diagnosis indicate the presence of metastatic cancer or early stage cancer.
    Type: Application
    Filed: January 30, 2007
    Publication date: December 24, 2009
    Applicant: The Scripps Research Institute
    Inventors: Peter Kuhn, Dena Marrinucci